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Abstracts tagged "Disease Activity"

  • Abstract Number: 1366 • 2013 ACR/ARHP Annual Meeting

    Abdominal Adiposity and Body Composition In Rheumatoid Arthritis: Relation With Disease Characteristics In A Case-Control Study

    Ivan Ferraz-Amaro1, Esmeralda Delgado-Frías2, Vanesa Hernandez-Hernandez3, Jose Ramon Muñiz4, Antonieta Gonzalez-Diaz5, Angeles Gomez Rodriguez-Bethencourt5 and Federico Diaz-Gonzalez6, 1Rheumatology, Servicio de Reumatologia. Hospital Universitario de Canarias, Tenerife, Spain, 2Rheumatology, Hospital Universitario de Canarias, La Laguna, Spain, 3Rheumatology, Rheumatology Service, Santa Cruz de Tenerife, Spain, 4Resonancia Magnética IMETISA, Resonancia Magnetica IMETISA, Santa Cruz de Tenerife, Spain, 5Servicio de Medicina Nuclear, Santa Cruz de Tenerife, Spain, 6University of La Laguna, Hospital Universitario de Canarias, La Laguna, Spain

    Background/Purpose: To determine the relationship between measures of body composition (total body composition derived from dual energy X-ray absorptiometry and abdominal adiposity through magnetic resonance…
  • Abstract Number: 862 • 2013 ACR/ARHP Annual Meeting

    Ten-Year Incidence of Self-Reported Nonvertebral Fractures in 9,720 Japanese Patients With Rheumatoid Arthritis: A Prospective Observational Cohort Study

    Kensuke Ochi1, Takefumi Furuya1, Eisuke Inoue2, Katsunori Ikari1, Atsuo Taniguchi2, Hisashi Yamanaka1 and Shigeki Momohara2, 1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 2Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan

    Ten-Year Incidence of Self-reported Nonvertebral Fractures in 9,720 Japanese Patients with Rheumatoid Arthritis: A Prospective Observational Cohort Study Background/Purpose: Although rheumatoid arthritis (RA) is a…
  • Abstract Number: 346 • 2013 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis, a More Severe Disease Than Psoriatic Arthritis? A Comparison Of Disease Activity In Patients With Psoriatic Arthritis and Rheumatoid Arthritis From The Swedish Early Psoriatic Arthritis Registry (SwePsA) and The Swedish Rheumatology Registry For Early RA (SRR)

    Gerd-Marie Alenius1, Tomas Husmark2, Elke Theander3, Per Larsson4, Mats Geijer5, Annika Teleman6 and Ulla R. C. Lindqvist7, 1Department of Public Health and Clinical Medicine, Rheumatology, Umeå University, Umeå, Sweden, 2Department of Rheumatology, Falu Hospital, Falun, Sweden, 3Section of Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, 4Dept of Rheumatology, Karolinska University Hospital, Stockholm, Sweden, 5Skåne University Hospital, Lund, Center for Medical Imaging and Physiology, Lund, Sweden, 6Department of Rheumatology, Spenshult Hospital, Oskarstrom, Sweden, 7Department of Medical Sciences, Rheumatology, University Hospital, Uppsala university, Uppsala, Sweden

    Background/Purpose: In clinical practise patients with psoriatic arthritis (PsA) seem to have milder disease expression compared with patients having rheumatoid arthritis (RA). Studies have, however,…
  • Abstract Number: 2905 • 2013 ACR/ARHP Annual Meeting

    Demethylation of ITGAL (CD11a) regulatory sequences in CD4+T lymphocytes of Systemic Sclerosis

    Yaoyao Wang1, Ye Shu2, Qing Wang1, Ming Zhao1, Gongping Liang1, Qianjin Lu1 and Rong Xiao1, 1Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China, 2Department of Dermatology, Hunan Children's Hospital, Changsha, China

    Background/Purpose: Systemic sclerosis (SSc) is an autoimmune connective tissue disease epitomized numerous cellular and humoral immunological abnormalities.   The immune system undoubtedly plays a pivotal…
  • Abstract Number: 2508 • 2013 ACR/ARHP Annual Meeting

    Clinical and Serological Discordance In The Systemic Lupus Erythematosus International Collaborating Clinics (SLICC) Cohort

    Murray B. Urowitz1, Dafna D. Gladman1, Nicole Anderson1 and Systemic Lupus Erythematosus International Collaborating Clinics SLICC2, 1Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Anti-DNA antibodies and serum complement levels are considered important biomarkers for disease activity in SLE.  Despite this many SLE patients present serologically active (positive…
  • Abstract Number: 2238 • 2013 ACR/ARHP Annual Meeting

    Comparison Of The Long-Term Outcome For Rheumatoid Arthritis Patients With  persistent Moderate Disease Activity Or Disease Remission During The First Year After Diagnosis: Data From The Espoir Cohort

    Bernard Combe1, Isabelle Logeart2, M. Belkacemi3, S Dadoun4, Jean-Pierre Daurès5 and Maxime Dougados6, 1Rheumatology, Lapeyronie Hospital, Montpellier I university, Montpellier, France, 2Pfizer, Paris, France, 3CHRU Montpellier, Montpellier, France, 4Paris-Pitié Salpêtrière University Hospital, Paris, France, 5Service BESPIM, CHU, Nimes, France, 6Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France

    Background/Purpose: The Treat to Target and EULAR recommendations highlighted the need for achieving and maintaining remission in patients with early RA. We investigated if early…
  • Abstract Number: 1708 • 2013 ACR/ARHP Annual Meeting

    Can People With Rheumatoid Arthritis Self Monitor Their Disease Activity?

    Noura AL Osaimi1, Erin Carruthers2, Charles H Goldsmith3,4, Paul M Adam5 and Diane Lacaille1,6, 1Medicine, University of British Columbia, Vancouver, BC, Canada, 2Arthritis Research Centre of Canada, Richmond, BC, Canada, 3Biostatistics, Arthritis Research Centre of Canada, Richmond, BC, Canada, 4Health Sciences, Simon Fraser University, Burnaby, BC, Canada, 5Rheumatology Liaison, Mary Pack Arthritis Centre, Vancouver, BC, Canada, 6Rheumatology, Arthritis Research Centre of Canada, University of British Columbia, Richmond, BC, Canada

    Background/Purpose: In rheumatoid arthritis (RA) the target for treatment is clinical remission or minimal disease activity. Active involvement of patients in monitoring their own disease…
  • Abstract Number: 1368 • 2013 ACR/ARHP Annual Meeting

    The Effect Of Vitamin D On Early Rheumatoid Arthritis: A Retrospective Cohort Analysis

    Faye A H Cooles1, Arthur G Pratt2,3,4, Wan-Fai Ng3,5, Terry J Aspray3 and John D Isaacs2, 1Musculoskeletal Research Group, Newcastle University, Newcastle upon Tyne, United Kingdom, 2Institute of Cellular Medicine (Musculoskeletal Research Group), NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals Foundation Trust and Newcastle University, Newcastle upon Tyne, United Kingdom, 3Musculoskeletal Directorate, The Freeman Hospital, Newcastle upon Tyne, United Kingdom, 4Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, 5Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle upon Tyne, United Kingdom

    Background/Purpose: There is increasing evidence that vitamin D has immunoregulatory properties in autoimmunity. In established rheumatoid arthritis (RA) there appears to be an inverse association…
  • Abstract Number: 812 • 2013 ACR/ARHP Annual Meeting

    Alveolar Bone Loss Is Associated With Disease Activity and ACPA Expression In Rheumatoid Arthritis

    Ted R. Mikuls1, Jeffrey Payne2, Fang Yu3, Geoffrey M. Thiele4, Shawneen Gonzalez2, Jeffrey Markt5, Jeremy Sokolove6, William H. Robinson7, Richard J. Reynolds8, Grant W. Cannon9, David McGowan10, Gail S. Kerr11, Robert Redman12, Andreas M. Reimold13, Garth Griffiths14, Mark Beatty2, Marian Schmid2, Paul Johnson2, Debra Bergman15, Bartlett C. Hamilton III16, Alan R. Erickson1 and James R. O'Dell17, 1Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, 2College of Dentistry, University of Nebraska Medical Center, Lincoln, NE, 3University of Nebraska Medical Center, Omaha, NE, 4Int Med/Sec of Rheum/Immun, Univ of Nebraska Med Ctr, Omaha, NE, 5Otol-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, NE, 6Stanford University, Palo Alto, CA, 7Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, 8Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 9Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, 10Dentistry, George E. Wahlen VA Medical Center, Salt Lake City, UT, 11Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, 12Dentistry, Washington DC VA, Georgetown and Howard University, Washington, DC, 13Rheumatology, Dallas VA and University of Texas Southwestern, Dallas, TX, 14Dentistry, Dallas VA and University of Texas Southwestern, Dallas, TX, 15Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 16University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, 17Dept of Internal Medicine, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Periodontitis (PD) has been implicated in rheumatoid arthritis (RA) pathogenesis including the expression of anti-citrullinated protein antibody (ACPA).  ACPA, in turn, have been shown…
  • Abstract Number: 300 • 2013 ACR/ARHP Annual Meeting

    Higher Disease Activity In Psoriatic Arthritis Is Associated With Elevated Total Cholesterol and Triglycerides

    Monalyn Labitigan1, Asha Shrestha1, George W. Reed2,3, Robert P. Magner4, Nicole Jordan5, Joel M. Kremer6, Jeffrey D. Greenberg7, Asena Bahce-Altuntas5 and Anna R. Broder1, 1Rheumatology, Albert Einstein College of Medicine, Bronx, NY, 2CORRONA, Inc., Southborough, MA, 3Orthopedics, University of Massachusetts Medical School, Worcester, MA, 4University of Massachusetts Medical School, Worcester, MA, 5Department of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, 6Center for Rheumatology, Albany Medical College, Albany, NY, 7Departments of Medicine (Rheum Div) and Hospital for Joint Diseases, New York Hospital for Joint Diseases, New York, NY

    Background/Purpose: Psoriatic Arthritis (PsA) is linked to both obesity and an increased cardiovascular risk.  However, the relationship between PsA disease activity and lipids, a major cardiovascular…
  • Abstract Number: 2879 • 2013 ACR/ARHP Annual Meeting

    Prognostic Value Of Minor Salivary Gland Assessments In Primary Sjögren’s Syndrome

    Anna Risselada1, A.a. Kruize2, J.A.G. van Roon3, F.P.J.G. Lafeber4 and J.W.J. Bijlsma4, 1Clinical immunology and Rheumatology, University Medical Center Utrecht, Utrecht, Netherlands, 2Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 3Rheumatology & Clinical Immunology/Lab Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 4Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands

    Background/Purpose: Salivary gland assessment is important for diagnosing primary Sjögren’s syndrome (pSS), as the lymphocytic focus score (LFS) is part of pSS classification criteria. Quantitative…
  • Abstract Number: 2511 • 2013 ACR/ARHP Annual Meeting

    Multicenter Validation Of The Lupus Activity Scoring Tool (LAST) As Compared To The Selena Sledai (SS) Modification

    Majed M. Khraishi1, Rana Aslanov2, Sanjay Dixit3, Krista Fudge4, Vandana Ahluwalia5 and Sarah Khraishi6, 1Nexus Clinical Research, St John's, NF, Canada, 2Clinical Epidemiology Department, Faculty of Medicine, Memorial University of Newfoundland, St.John's, NF, Canada, 3McMaster University, Hamilton, ON, Canada, 4Medical Consultants of West Newfoundland, Western Memorial Hospital, Corner Brook, NF, Canada, 5Past President, Ontario Rheumatology Association, Brampton, ON, Canada, 6Nexus Clinical Research, Memorial University of Newfoundland, St.John's, NF, Canada

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic immune modulated disease with variable clinical manifestations. New advances in the management of SLE mandated closer monitoring…
  • Abstract Number: 2241 • 2013 ACR/ARHP Annual Meeting

    Assessing Significant Flares In Rheumatoid Arthritis: Validity Of The Outcome Measures In Rheumatology Preliminary Flare Questions In The Canadian Early Arthritis Cohort

    Susan J. Bartlett1,2, Clifton O. Bingham III3, Ernest Choy4, Juan Xiong5, Gilles Boire6, Boulos Haraoui7, Janet E. Pope8,9, J. Carter Thorne10, Carol A. Hitchon11, Diane Tin12, Edward C. Keystone13 and Vivian P. Bykerk13,14, 1Clinical Epidemiology, McGill University, Montreal, QC, Canada, 2Division of Rheumatology, Johns Hopkins University, Baltimore, MD, 3Rheumatology, Johns Hopkins University, Baltimore, MD, 4Section of Rheumatology, Cardiff University, Institute of Infection and Immunity, Cardiff, United Kingdom, 5Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 6Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, 7Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada, 8St Joseph Health Care, London, ON, Canada, 9Univ of Western Ontario, London, ON, Canada, 10Southlake Regional Health Centre, Newmarket, ON, Canada, 11Rheumatology, University of Manitoba, Winnipeg, MB, Canada, 12The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, 13Medicine, Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, 14Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY

    Background/Purpose: Rheumatoid arthritis (RA) flares are common, poorly defined, and understudied. A tool is needed to measure significant RA flares that may signal need for…
  • Abstract Number: 1667 • 2013 ACR/ARHP Annual Meeting

    Serum S100A8/S100A9 and S100A12 As a Marker Of Disease Activity In Giant Cell Arteritis

    Jason Springer1, Dirk Holzinger2, Gary S. Hoffman3, Paul A. Monach4, Thomas Hamilton5, Carol A. Langford6, Dirk Foell7, David Cuthbertson8, Colin O'Rourke9, Simon Carette10, Nader A. Khalidi11, Carol McAlear12, Christian Pagnoux10, Philip Seo13, Kenneth J. Warrington14, Steven R. Ytterberg15, Thomas Vogl16, Peter A. Merkel17, Johannes Roth18 and Rula Hajj-Ali19, 1Division of Allergy, Clinical Immunology and Rheumatology, University of Kansas Medical Center, Kansas City, KS, 2Institute of Immunology, University Muenster, Muenster, Germany, 3Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, OH, 4Rheumatology, Boston University, Boston, MA, 5Cleveland Clinic, Cleveland, OH, 6Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH, 7Department of Pediatric Rheumatology and Immunology, University of Münster, Münster, Germany, 8Department of Biostatistics, University of South Florida, Tampa, FL, 9Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, 10Division of Rheumatology, University of Toronto, Toronto, ON, Canada, 11Internal Medicine/Rheumatology, McMaster University, Hamilton, ON, Canada, 12University of Pennsylvania, Philadelphia, PA, 13Rheumatology Division, Johns Hopkins Vasculitis Center, Johns Hopkins University, Baltimore, MD, 14Division of Rheumatology, Mayo Clinic, Rochester, MN, 15Rheumatology Division, Mayo Clinic, Rochester, MN, 16Institute of Immunology, University of Muenster, Muenster, Germany, 17Division of Rheumatology, Vasculitis Center, University of Pennsylvania, Philadelphia, PA, 18Immunology, Institute of Immunology University of Muenster, Muenster, Germany, 19Cleveland Clinic Foundation, Cleveland, OH

     Background/Purpose: The S100 proteins (S100A8/9 complex and S100A12) are calcium binding proteins expressed during myeloid differentiation.  S100 proteins are phagocyte-specific proteins that have been demonstrated…
  • Abstract Number: 1341 • 2013 ACR/ARHP Annual Meeting

    Significantly Less Glucocorticoids and Better Patient-Reported Outcomes In Women With Early Inflammatory Arthritis Using Oral Contraceptives Compared To Never Users

    Gisela Westhoff1, Rainer H. Straub2, Frank Buttgereit3, Johanna Callhoff4 and Angela Zink5, 1Epidemiology Unit, German Rheumatism Research Center Berlin, Berlin, Germany, 2Department of Internal Medicine I, Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, University Hospital of Regensburg, Regensburg, Germany, 3Charité - Universitätsmedizin Berlin, Berlin, Germany, 4German Rheumatism Research Center, Berlin, Germany, 5German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany

    Background/Purpose: Data on the effects of oral contraceptives (OC) on the course of inflammatory arthritis (IA) are controversial. However, a recent analysis of data from…
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