Abstracts tagged "Disease Activity"

Abstract Number: 2871 • 2013 ACR/ARHP Annual Meeting
Validation Of The FLARE Self-Report Questionnaire For Assessing FLARE Out Of The Clinical Visit In Rheumatoid Arthritis
Jacques Morel¹, Jean-Marie Berthelot², Arnaud L. Constantin³, Michel De Bandt⁴, Philippe Gaudin⁵, Olivier Vittecoq⁶, Jean Francis Maillefert⁷, Olivier Meyer⁸, Thao Pham⁹, Alain Saraux¹⁰, Elisabeth Solau Gervais¹¹, Elisabeth Spitz¹², Daniel Wendling¹³, Francis Guillemin¹⁴ and Bruno Fautrel¹⁵, ¹Department of Rheumatology, Hôpital Lapeyronie, Montpellier, France, ²Rheumatology Unit, Nantes University Hospital, Nantes, France, ³Rheumatology, Purpan University Hospital, Toulouse, France, ⁴Rhumatologie Et Médecine Interne, Centre hospitalier Universitaire de Fort de France, Fort de France, Martinique, ⁵Rheumatology Department, CHU Hôpital Sud, Grenoble Teaching Hospital, Echirolles, France, ⁶Rheumatology, Department of Rheumatology, Rouen University Hospital & Inserm 905, Institute for Biomedical Research, University of Rouen, Rouen, France, ⁷University Hospital, Department of Rheumatology, Dijon, France, ⁸Rheumatology, Bichat University Hospital, Paris, France, ⁹Rheumatology Department, Sainte Marguerite Hospital, Marseille, France, ¹⁰Rhumatologie, CHU de la Cavale Blanche, Brest Cedex, France, ¹¹Departement of Rheumatology, CHU de Poitiers, Poitiers, France, ¹²UFR Sciences Humaines et Arts, APEMAC-EA4360, Metz, France, ¹³Rheumatology, University Hospital, Besancon, France, ¹⁴CHU Nancy, Clinical Epidemiology and Evaluation, Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, Nancy, France, ¹⁵Paris 6 – Pierre et Marie Curie University; AP-HP, Rheumatology, Pitié-Salpêtrière Hospital, - GRC-UPMC 08 – EEMOIS, Paris, France
Background/Purpose: Defining flare in rheumatoid arthritis (RA) raises a complex issue related to the difference in perception or concept of flare between patients or health…
Abstract Number: 2446 • 2013 ACR/ARHP Annual Meeting
Opiate Use In Patients With Ankylosing Spondylitis
John D. Reveille¹, Michael M. Ward², MinJae Lee³, Mohammad Rahbar⁴, Manouchehr Ardjomand-Hessabi⁵, Laura A. Diekman⁵, Matthew A. Brown⁶, Lianne S. Gensler⁷ and Michael H. Weisman⁸, ¹Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, ²Bldg 10 CRC Rm 4-1339, NIAMS/NIH, Bethesda, MD, ³Medicine, University of Texas Health Science Center at Houston, Houston, TX, ⁴The University of Texas Health Science Center at Houston, Houston, TX, ⁵Rheumatology, The University of Texas Health Science Center at Houston, Houston, TX, ⁶Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, Australia, ⁷Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁸Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA
Background/Purpose: Prescription opiates are commonly prescribed in patients with chronic pain, yet there is no evidence that these drugs ameliorate disease progression, and are associated with numerous…
Abstract Number: 2196 • 2013 ACR/ARHP Annual Meeting
Aberrant IgG Glycosylation Is Associated With Active Disease In Juvenile Idiopathic Arthritis Patients
Esperanza Cleland, Brooke Gilliam and Terry L. Moore, Internal Medicine/Rheumatology, Saint Louis University, Saint Louis, MO
Background/Purpose: Aberrant glycosylation of IgG is an abnormality of humoral immunity in patients with rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) that is not…
Abstract Number: 1550 • 2013 ACR/ARHP Annual Meeting
Validation Of The Ankylosing Spondylitis Disease Activity Score and Effectiveness Of Infliximab In The Treatment Of Ankylosing Spondylitis Over 4 Years: The Canadian Experience
Proton Rahman¹, Denis Choquette², Majed M. Khraishi³, William G. Bensen⁴, Saeed A. Shaikh⁵, Dalton E. Sholter⁶, Maqbool K. Sheriff⁷, Emmanouil Rampakakis⁸, John S. Sampalis⁸, Francois Nantel⁹, Susan M. Otawa¹⁰, Allen J. Lehman¹⁰ and May Shawi¹¹, ¹Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ²Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, ³Nexus Clinical Research, St John's, NF, Canada, ⁴Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, ⁵Medicine, McMaster University, St Catharines, ON, Canada, ⁶Rheumatology Associates, Edmonton, AB, Canada, ⁷Nanaimo Regional General Hospital, Nanaimo, BC, Canada, ⁸JSS Medical Research, Montreal, QC, Canada, ⁹Janssen Inc., Toronto, ON, Canada, ¹⁰Medical Affairs, Janssen Inc., Toronto, ON, Canada, ¹¹Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada
Background/Purpose: The efficacy of anti-TNF in the management of Ankylosing Spondylitis (AS) has been demonstrated in numerous controlled clinical trials. The objective of this study…
Abstract Number: 1322 • 2013 ACR/ARHP Annual Meeting
Osteoprotegerin and TNF-Related Apoptosis Inducing Ligand Are Respectively Predictive Factors Of Remission and Erosion In Early Rheumatoid Arthritis Patients Included In The French Cohort Espoir
Rachel Audo¹, Laura Papon¹, Claire I. Daien^1,2, Cédric Lukas³, Bernard Combe², Olivier Vittecoq⁴, Michael Hahne¹ and Jacques Morel⁵, ¹IGMM, CNRS UMR5535, Montpellier, Montpellier, France, ²Department of Rheumatology, Lapeyronie Hospital, Montpellier, France, ³Immuno-Rhumatologie, Hopital Lapeyronie, Montpellier, France, ⁴Rheumatology, Rouen University Hospital & Inserm905, University of Rouen, Rouen Cedex, France, ⁵Dpartment of Rheumatology, Lapeyronie Hospital, Montpellier, France
Background/Purpose: TNF-Related Apoptosis Inducing Ligand (TRAIL) is a member of the TNF familly. Its soluble receptor Osteoprotegerin (OPG) also inhibits Receptor activator of nuclear factor…
Abstract Number: 665 • 2013 ACR/ARHP Annual Meeting
DNA hypermethylation of Forkhead box protein 3 (FOXP3) locus leads to quantitative defects of regulatory T cells in systemic sclerosis
Yaoyao Wang¹, Ye Shu², Qing Wang¹, Ming Zhao¹, Gongping Liang¹, Qianjin Lu¹ and Rong Xiao¹, ¹Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China, ²Department of Dermatology, Hunan Children's Hospital, Changsha, China

Background/Purpose: Systemic sclerosis (SSc) is a systemic autoimmune disease of which the etiology and pathogenesis remains complex and poorly understood. Attention has recently been directed…
Abstract Number: 25 • 2013 ACR/ARHP Annual Meeting
SLE Flares Are Characterized By Generalized Polyclonal Expansions Of Antibody Secreting Cells Without Preference For Autoimmune Responses
H. Travis Ichikawa, Medicine, Emory University, Atlanta, GA
Background/Purpose: Increased circulating antibody secreting cells (ASC), including both CD138- plasmablasts and CD138+ plasma cells (PB/PC), correlate with SLE activity and are prominent during Lupus…

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