Abstracts tagged "Disease Activity and interferons"

Abstract Number: 2384 • ACR/ARHP Annual Meeting 2016
Variable Clinical Phenotypes and Relation of Interferon Signature with Disease Activity in ADA 2 Deficiency
Antonella Insalaco¹, Gianmarco Moneta², Manuela Pardeo¹, Chiara Passarelli³, Camilla Celani⁴, Virginia Messia⁴ and Fabrizio De Benedetti¹, ¹Division of Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Italy, Rome, Italy, ²Division of Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Italy, Roma, Italy, ³Ospedale Pediatrico Bambino Gesù IRCCS, Unit of Medical Genetics, Laboratory of Cytogenetics and Molecular Genetics, Rome, Italy, ⁴Division of Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Italy
Background/Purpose: The deficiency of adenosindeaminase 2 (DADA2) is a recently described autosomal recessive autoinflammatory disease, caused by mutations of CECR1 and characterized by early onset…