Abstracts tagged "differentiation and Treg"

Abstract Number: 116 • ACR/ARP Annual Meeting 2019
Defective EZH2 Expression Attenuates Treg Differentiation in Rheumatoid Arthritis
Xinyue Xiao¹, Yueting Li ², Hua Chen ¹ and Xuan Zhang ², ¹Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Clinical Immunology Center, Chinese Academy of Medical Sciences and Peking Union Medical College; The Ministry of Education Key Laboratory, Beijing, China, Beijing, Beijing, China (People's Republic), ²Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Clinical Immunology Center, Chinese Academy of Medical Sciences and Peking Union Medical College; The Ministry of Education Key Laboratory, Beijing, China, Beijing, China (People's Republic)
Background/Purpose: To explore the role of EZH2, a histone methylation regulator, in the pathogenesis of rheumatoid arthritis (RA).Methods: Forty treatment-naïve patients with active disease and…