Abstracts tagged "differentiation and chronic inflammation"

Abstract Number: 996 • ACR/ARP Annual Meeting 2019
The Role of Flip in Differentiation and Survival of Synovial Tissue Resident Macrophages
Qi Huang¹, Renee Doyle ¹, Shang-Yang Chen ², Alexander Misharin ³, Deborah Winter ⁴ and Richard Pope ⁵, ¹Northwestern University Feinberg School of Medicine, Chicago, IL, ²Northwestern University, Chicago, ³Northwestern University Feinberg School of Medicine, chicago, ⁴Northwestern University Feinberg School of Medicine, Division of Rheumatology, Chicago, ⁵Northwestern University Feinberg School of Medicine, Division of Rheumatology, chicago, IL
Background/Purpose: We previously identified that under homeostatic conditions Flip was necessary for macrophage (MΦ) survival. The mechanisms responsible for the differentiation of monocyte-derived MΦs into…