Abstracts tagged "Diagnostic Tests"

Abstract Number: 1421 • 2014 ACR/ARHP Annual Meeting
Preclinical Interstitial Lung Disease in Early Rheumatoid Arthritis
Javier Narváez¹, Alejandro Robles Perez², Maria Molina Molina³ and Joan Miquel Nolla⁴, ¹Rheumatology, Hospital Universitario de Bellvitge. Barcelona. Spain, Barcelona, Spain, ²Pneumology, Hospital Universitario de Bellvitge, Barcelona, Spain, ³Hospital Universitario de Bellvitge, Barcelona, Spain, ⁴Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain
Background/Purpose: Early detection and treatment of interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA) may ameliorate disease progression. The objective of the present…
Abstract Number: 1309 • 2014 ACR/ARHP Annual Meeting
Does Anti-C1q Antibody Have Diagnostic and Prognostic Roles in Childhood – Onset Systemic Lupus Erythematosus?
Thaschawee Arkachaisri¹, Joo Guan Yeo², Justin Hung Tiong Tan³, Sook Fun Hoh⁴, Lena Das³ and Jing Yao Leong², ¹Rheumatology & Immunology, KK Women's and Children's Hospital, Singapore, Singapore, ²Children Intensive Care Unit (CICU), KK Women's and Children's Hospital, Singapore, Singapore, ³Rheumatology and Immunology, KK Women's and Children's Hospital, Singapore, Singapore, ⁴Nursing, KK Women's and Children's Hospital, Singapore, Singapore
Background/Purpose: Biomarkers proven to be effective in aSLE patients may not directly apply to cSLE unless validation is done. Existing evidences have shown immunopathogenic roles…
Abstract Number: 2772 • 2014 ACR/ARHP Annual Meeting
The Use of Imaging in the Diagnosis of Polymyalgia Rheumatica: Systematic Literature Review and Meta-Analysis
Sarah Mackie¹, Gouri Koduri², Catherine L. Hill^3,4, Andrew Hutchings⁵, Richard J. Wakefield⁶, Bhaskar Dasgupta⁷ and Jeremy Wyatt⁸, ¹NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, ²Rheumatology, York Teaching Hospital NHS Foundation Trust, York, United Kingdom, ³Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, Australia, ⁴Discipline of Medicine, University of Adelaide, Adelaide, Australia, ⁵Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom, ⁶NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁷Department of Rheumatology, Southend University Hospital, Essex, United Kingdom, ⁸Leeds Insitute of Health Sciences, University of Leeds, Leeds, United Kingdom
Background/Purpose ACR/EULAR provisional classification criteria for polymyalgia rheumatica (PMR) incorporate musculoskeletal ultrasound of shoulder and hip (bursitis and synovitis given equal weight). Our objective was…
Abstract Number: 1308 • 2014 ACR/ARHP Annual Meeting
Antinucleosome Antibodies As Potential Diagnostic and Prognostic Biomarkers in Childhood Onset Systemic Lupus Erythematosus
Thaschawee Arkachaisri¹, Joo Guan Yeo², Justin Hung Tiong Tan³, Sook Fun Hoh⁴, Lena Das³ and Jing Yao Leong², ¹Rheumatology & Immunology, KK Women's and Children's Hospital, Singapore, Singapore, ²Children Intensive Care Unit (CICU), KK Women's and Children's Hospital, Singapore, Singapore, ³Rheumatology and Immunology, KK Women's and Children's Hospital, Singapore, Singapore, ⁴Nursing, KK Women's and Children's Hospital, Singapore, Singapore
Background/Purpose: The role of antinucleosome antibodies (ANuA) in the immunopathogenesis of SLE is evident. ANuA was shown to be a good, if not better than…
Abstract Number: 2588 • 2014 ACR/ARHP Annual Meeting
Which Characteristics of Inflammatory Back Pain (CBP) Forecast the Presence of HLA-B27? Results from the Esperanza Cohort
Victoria Navarro-Compán¹, Juan Jose Aznar², Luis F Linares³, Eduardo Collantes-Estévez⁴, Robert B. M. Landewé⁵, Désirée van der Heijde⁶ and Pedro Zarco⁷, ¹Rheumatology, University Hospital La Paz and Leiden University Medical Center, Madrid, Spain, ²Hospital de Mérida, Mérida (Badajoz), Spain, ³University Hospital Virgen de la Arrixaca, Murcia, Spain, ⁴IMIBIC/University Hospital Reina Sofía, Córdoba, Spain, Córdoba, Spain, ⁵Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, ⁶Leiden University Medical Center, Leiden, Netherlands, ⁷Rheumatology Department, Fundación Hospital Alcorcon, Alcorcon, Madrid, Spain
Background/Purpose: CBP is often the starting point for a suspicion of axSpA. In the ASAS-criteria for axial SpA either MRI of the SI-joints or HLA-B27-testing…
Abstract Number: 1258 • 2014 ACR/ARHP Annual Meeting
Enzyme-Linked Immunosorbent Assays for Detection of Anti-Transcriptional Intermediary Factor-1 Gamma and Anti-Mi-2 Autoantibodies in Dermatomyositis: Utility and Crossreactivity
Manabu Fujimoto¹, Akihiro Murakami², Shunsuke Kurei², Akiko Kuwajima³, Yasuhiro Fujisawa¹, Atsushi Kawakami⁴, Michiaki Mishima⁵, Shinji Sato⁶, Mariko Seishima⁷, Takafumi Suda⁸, Tsuneyo Mimori⁹, Kazuhiko Takehara¹⁰ and Masataka Kuwana¹¹, ¹Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ²Medical & Biological Laboratories Co., Ltd, Nagaya, Japan, ³Medical & Biological Laboratories Co.,Ltd., Nagoya, Japan, ⁴Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁵Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan, Kyoto, Japan, ⁶Division of Rheumatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan, ⁷Department of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan, ⁸Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan, ⁹Dept of Rheum & Clinical Immunology, Kyoto Univ Grad Schl of Med, Kyoto, Japan, ¹⁰Dermatology, Kanazawa University, Kanazawa, Japan, ¹¹Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
Background/Purpose Anti-transcriptional intermediary factor 1 (TIF-1) and anti-Mi-2 antibodies (Abs) are myositis-specific autoantibodies (MSA) selectively detected in dernatomyositis (DM) patients. Anti-TIF-1 Ab is frequently found…
Abstract Number: 2586 • 2014 ACR/ARHP Annual Meeting
Which Characteristics of Inflammatory Back Pain (CBP) Forecast the Presence of Sacroiliitis on Magnetic Resonance Imaging (MRI)? Results from the Esperanza Cohort
Victoria Navarro-Compán¹, Raquel Almodóvar González², Azucena Hernández³, Emma Beltrán⁴, Eugenio De Miguel⁵, Robert B. M. Landewé⁶, Désirée van der Heijde⁷ and Pedro Zarco⁸, ¹Rheumatology, University Hospital La Paz and Leiden University Medical Center, Madrid, Spain, ²Rheumatology Unit, Hospital Universitario Fundación Alcorcón, Madrid, Spain, ³Rheumatology, Hospital Virgen de la Salud, Toledo, Spain, ⁴University General Hospital of Valencia, Valencia, Spain, ⁵Rheumatology, University Hospital La Paz - IdiPaz, Madrid, Spain, ⁶Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, ⁷Leiden University Medical Center, Leiden, Netherlands, ⁸Rheumatology Department, Fundación Hospital Alcorcon, Alcorcon, Madrid, Spain
Background/Purpose: CBP is often the starting point for a suspicion of axSpA. In the ASAS-criteria for axial SpA either MRI of the SI-joints or HLA-B27-testing…
Abstract Number: 400 • 2014 ACR/ARHP Annual Meeting
Clinical Utility of 14-3-3η in the Evaluation of Inflammatory Arthritis
Lance Feller¹, Paul Tuttle IV² and Terry L. Moore³, ¹Rheumatology, Saint Louis University, St. Louis, MO, ²Rheumatology, Saint Louis University, Saint Louis, MO, ³Internal Medicine/Rheumatology, Saint Louis University, Saint Louis, MO
Background/Purpose 14-3-3 proteins are chaperonins found in all eukaryotic cells. There are multiple isoforms which are thought to be involved in intracellular signaling and transcription…
Abstract Number: 2553 • 2013 ACR/ARHP Annual Meeting
The Clinical Value Of Testing For Aphl, a New ELISA Kit With a Unique Phospholipid Mixture In Patients With Systemic Lupus Erythematosus (SLE)
Savino Sciascia¹, Giovanni Sanna², Veronica Murru³, Munther A. Khamashta⁴ and Maria Laura Bertolaccini³, ¹Department of Rare, Immunologic, Hematologic and Immunohematologic Diseases, Centro di Immunopatologia e Documentazione su Malattie rare, Torino, Italy, ²Louise Coote Lupus Unit, St. Thomas' Hospital, London, United Kingdom, ³Lupus Research Unit, The Rayne Institute, Kings College London School of Medicine, London, United Kingdom, ⁴Lupus Research Unit, The Rayne Institute, St Thomas Hospital, Kings College London School of Medicine, London, United Kingdom
Background/Purpose: Antibodies directed to APhL (a mixture of phospholipids) have been reported to predict APS more reliably than aCL tests. We designed this study to…
Abstract Number: 2525 • 2013 ACR/ARHP Annual Meeting
An Assay Panel Combining Cell Bound Complement Activation Products With Autoantibodies To Extractable Nuclear Antigens and Mutated Citrullinated Vimentin Helps With The Differential Diagnosis Of Systemic Lupus Erythematosus
Chaim Putterman¹, Richard Furie², R. Ramsey-Goldman³, Anca Askanase⁴, Jill P. Buyon⁵, Kenneth C. Kalunian⁶, W. Winn Chatham⁷, Elena M. Massarotti⁸, Emily C. Somers⁹, Irene Blanco¹⁰, Puja Chitkara¹¹, Nicole Jordan¹², Kyriakos A. Kirou¹³, Arthur Weinstein¹⁴, Susan Manzi¹⁵, Joseph M. Ahearn¹⁶, Claudia Ibarra¹⁷, Derren Barken¹⁸ and Thierry Dervieux¹⁹, ¹Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ²North Shore-LIJ Health System, Lake Success, NY, ³Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴NYU School of Medicine, New York, NY, ⁵Medicine, Division of Rheumatology, NYU School of Medicine, New York, NY, ⁶UCSD School of Medicine, La Jolla, CA, ⁷University of Alabama at Birmingham, Birmingham, AL, ⁸Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁹IntMed, Environmental Health, and OB/GYN, University of Michigan, Ann Arbor, MI, ¹⁰Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ¹¹Rheumatology, SDAMC, San Diego, CA, ¹²Department of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ¹³Hospital for Special Surgery, New York, NY, ¹⁴Washington Hospital Center, Washington, DC, ¹⁵Division of Rheumatology, University of Pittsburgh School of Medicine, Pittsburgh, PA, ¹⁶Lupus Center of Excellence, West Penn Allegheny Health System, Pittsburgh, PA, ¹⁷Clinical Laboratory, Exagen Diagnostics, Vista, CA, ¹⁸Exagen Diagnostics, Vista, CA, ¹⁹Research and Development, Exagen Diagnostics, Vista, CA
Background/Purpose: We previously established the value of cell-bound complement activation products (CBCAPS) in the diagnosis of systemic lupus erythematosus (SLE) (CAPITAL study). The purpose of…
Abstract Number: 2274 • 2013 ACR/ARHP Annual Meeting
Assessment Of The Diagnostic Accuracy Of Different Strategies For Health Fair Case-Finding For Undiagnosed Inflammatory Arthritis
Kaylynn Aiona¹, Christopher C. Striebich², M. Kristen Demoruelle³, Julia J. Rhiannon⁴, Stuart M. Weisman⁵, Marie L. Feser³, Lezlie A. Derber⁵, James H. Goddard⁶, Stacey Brake⁶, Jill Lysengen⁷, Laura Rosseisen⁷, John E. Hokanson¹, Anna E. Baron¹, Jill M. Norris⁸, V. Michael Holers⁹ and Kevin D. Deane³, ¹Colorado School of Public Health, Aurora, CO, ²University of Colorado Denver, Aurora, CO, ³Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁴Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁵University of Colorado School of Medicine, Division of Rheumatology, Aurora, CO, ⁶9Health Fair, Denver, CO, ⁷Arthritis Foundation, Great West Region, Denver Office, Denver, CO, ⁸Epidemiology, Colorado School of Public Health, Aurora, CO, ⁹Rheumatology Division, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Early treatment of inflammatory arthritis (IA), and especially rheumatoid arthritis (RA), leads to improved outcomes, although diagnostic delays may impede timely treatment. We…
Abstract Number: 1891 • 2013 ACR/ARHP Annual Meeting
Proteomic Profile Of Tears: Can It Help To Diagnose Juvenile Arthritis – Associated Uveitis Prior To The Clinical Signs Of Joints Inflammation
Vyacheslav Chasnyk¹, Sergei Nekhai², Alla Hynes³, Tatiana Ammosova⁴, Yuri Obukhov⁴, Ekaterina Gaidar⁵, Anatolyi Kononov⁵, Margarita Dubko⁶, Elena Serogodskaia⁶ and Tatiana Nikitina⁵, ¹Hospital Pediatry, State Pediatric Medical University, Saint-Petersburg, Russia, ²Department of Medicine, Center for Sickle Cell Disease, Howard University, Washington, DC, ³Eye Care Physicians and Surgeons, Winchester, VA, ⁴Howard University, Washington, DC, ⁵Saint-Petersburg State Pediatric Medical University, St. Petersburg, Russia, ⁶State Pediatric Medical University, Saint-Petersburg, Russia
Background/Purpose: Approximately 6% of all cases of uveitis arise in children (Nguyen, Foster, 1998). One of the common causes of uveitis is Juvenile Idiopathic Arthritis…
Abstract Number: 1578 • 2013 ACR/ARHP Annual Meeting
Decreased Sensitivity Of a Commercial Anti-dsDNA Assay In Patients With Moderately To Severely Active Systemic Lupus Erythematosus
Munther A. Khamashta¹, Gabor G. Illei², Stephen Yoo², Liangwei Wang³ and Warren Greth², ¹Lupus Research Unit, The Rayne Institute, St Thomas Hospital, Kings College London School of Medicine, London, United Kingdom, ²Clinical Development, MedImmune, LLC, Gaithersburg, MD, ³Biostatistics, MedImmune, LLC, Gaithersburg, MD
Background/Purpose: Anti-dsDNA autoantibodies are highly specific for SLE. Anti-dsDNA positivity is an important eligibility criterion in many SLE studies, and decreases in anti-dsDNA levels are…
Abstract Number: 1390 • 2013 ACR/ARHP Annual Meeting
Chaperonin Protein 14-3-3n (eta) In Rheumatoid Arthritis and Arthritogenic Viral Infections
Stanley J. Naides, Olga S Zhukov, Rania W Abolhosn and Joanna M Popov, Immunology, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA
Background/Purpose: The 14-3-3 proteins are ubiquitously-expressed intracellular chaperonins. Expression of the η (eta) isoform is restricted to synovial and CNS tissues. Extracellular 14-3-3η induces proinflammatory…
Abstract Number: 1325 • 2013 ACR/ARHP Annual Meeting
A Novel Index To Identify Interstitial Lung Disease In Rheumatoid Arthritis Patients
Jose Felix Restrepo¹, Inmaculada Del Rincon², Roy W. Haas³, Daniel F. Battafarano⁴ and Agustin Escalante⁵, ¹Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX, ²Rheumatology, University of Texas Health Science Center, San Antonio, TX, ³Dept. of Medicine-Rheumatology, University of Texas Health Science Center, San Antonio, TX, ⁴Medicine / MCHE-MDR, San Antonio Military Medical Center, San Antonio, TX, ⁵Dept. of Medicine-Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX
A Novel Index to Identify Interstitial Lung Disease in Rheumatoid Arthritis Patients José Félix Restrepo1, Inmaculada del Rincón1, Roy W Haas1, Daniel F Battafarano2, Agustín Escalante1…

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