Abstracts tagged "Diagnostic Tests"

Abstract Number: 1995 • 2014 ACR/ARHP Annual Meeting
Design and Implementation of a Clinical Teaching Tool for Approach to Children with Suspected New Rheumatologic Diagnosis
Kristen Hayward¹ and Jennifer Hrachovec², ¹Pediatric Rheumatology, Seattle Children's Hospital, Seattle, WA, ²Clincal Effectiveness, Seattle Children's Hospital, Seattle, WA
Background/Purpose Approximately 1 in 1000 children suffer from a rheumatologic disorder. Despite the relative frequency of these conditions, there is a shortage of pediatric rheumatologists…
Abstract Number: 1867 • 2014 ACR/ARHP Annual Meeting
Mandibular Movement in Healthy Individuals from 4-17 Years of Age
Peter Stoustrup¹, Kasper Dahl Kristensen^2,3, Annelise Küseler⁴, Thomas Klit Pedersen^5,6 and Troels Herlin⁷, ¹Section of Orthodontics, University of Aarhus, Aarhus C, Denmark, ²Section of Orthodontics, University of Aarhus, Denmark, 8000 Aarhus, Denmark, ³Specialist Oral Health Center for Western Norway, Rogaland Stavanger, Norway, ⁴Section of Orthodontics, Aarhus University, Aarhus, Denmark, ⁵Section or Orthodontics, Aarhus University, Aarhus, Denmark, ⁶Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark, ⁷Pediatric Rheumatology Clinic, Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark
Background/Purpose: Assessment of mandibular movement capacity is an important part of the clinical orofacial examination of patients with juvenile idiopathic arthritis (JIA). The aim of…
Abstract Number: 1756 • 2014 ACR/ARHP Annual Meeting
Molecular Diagnosis Reveals a Surprising Prevalence of Limited Gpa Among Patients with Orbital Inflammatory Diseases
James T. Rosenbaum¹, Dongseok Choi², Christine Harrington³, Patrick Stauffer⁴, David Wilson⁵, Seema Gupta⁴, Roger Dailey⁴, John Ng⁴, Eric Steele⁴, Patrick Yeatts⁶, Peter Dolman⁷, Valerie White⁷, Gerald Harris⁸, Craig Czyz⁹, Jill Foster⁹, Deepak Edward¹⁰, Hind Alkatan¹⁰, Bobby Korn¹¹, Don Kikkawa¹², Dinesh Selva¹³, Sander Dubovy¹⁴, Chris Alabiad¹⁵, David Tse¹⁵, Michael Kazim¹⁶, Payal Patel¹⁶ and Stephen R. Planck¹⁷, ¹OHSU, Portland, OR, ²Casey Eye Institute, Oregon Health and Science University, Portland, OR, ³Integrated Genomics, Oregon Health & Science University, Portland, OR, ⁴Oregon Health & Science University, Portland, OR, ⁵Casey Eye Institute/Ophthalmology, Oregon Health & Science University, Portland, OR, ⁶Ophthalmology, Wake Forest University, Winston-Salem, NC, ⁷University of British Columbia, Vancouver, BC, Canada, ⁸Medical College of Wisconsin, Milwaukee, WI, ⁹Ohio State Univeristy, Columbus, OH, ¹⁰King Khaled Eye Hospital, Riyadh, Saudi Arabia, ¹¹University of California, San Diego, San Diego, CA, ¹²Ophthalmology, University of California, San Diego, San Diego, CA, ¹³Royal Adelaide Hospital, Adelaide, Australia, ¹⁴University of Miami, Miami, FL, ¹⁵Ophthalmology, University of Miami, Miami, FL, ¹⁶Columbia University, New York City, NY, ¹⁷Casey Eye Inst/Ophthalmology, Oregon Health & Science University, Portland, OR
Background/Purpose: Gene expression profiling provides diagnostic and therapeutic information in several malignancies, but its role in evaluating inflammatory disease is relatively untested. We hypothesized that…
Abstract Number: 1762 • 2014 ACR/ARHP Annual Meeting
The Muscle Biopsy Is a Useful and Noninvasive Procedure in Diagnosing Systemic Vasculitis Affecting Small-to-Medium-Sized Vessels: A Prospective Evaluation
Takahiro Nunokawa¹, Takayasu Kise¹, Naoto Yokogawa², Kota Shimada¹ and Shoji Sugii², ¹Department of Rheumatic diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan, ²Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan
Background/Purpose: Histopathological confirmation is required for the diagnosis of systemic vasculitis. However, patients suspected of vasculitis often only have lesions with a low diagnostic yield…
Abstract Number: 1695 • 2014 ACR/ARHP Annual Meeting
Validation of Vesmeter As a Diagnostic Tool of Scleroderma
Yoshihiro Hishitani^1,2, Yoshihito Shima¹, Toshio Tanaka¹ and Atsushi Kumanogoh¹, ¹Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine, Suita, Japan, ²Internal Medicine, Kinki Central Hospital, Itami, Japan
Background/Purpose: Objective method to evaluate the skin involvement in the patients with scleroderma has not been definitely established. We have developed Vesmeter, a computer-linked device…
Abstract Number: 1691 • 2014 ACR/ARHP Annual Meeting
Systemic Sclerosis Patients with Pulmonary Hypertension Have a Lower Change in End Tidal Carbon Dioxide Following Three Minutes of Step Exercise Than Systemic Sclerosis Patients without Pulmonary Hypertension: A Cross-Sectional Study
Elana J. Bernstein¹, Jessica K. Gordon², Robert F. Spiera², Wei-Ti Huang³, Evelyn M. Horn⁴ and Lisa A. Mandl², ¹Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ²Rheumatology, Hospital for Special Surgery, New York, NY, ³Biostatistics, Hospital for Special Surgery, New York, NY, ⁴Cardiology, New York Presbyterian Hospital/Weill Cornell Medical College, New York, NY
Background/Purpose: Pulmonary hypertension (PH) is a leading cause of death in patients with systemic sclerosis (SSc). Transthoracic echocardiogram and pulmonary function testing are standard noninvasive…
Abstract Number: 1629 • 2014 ACR/ARHP Annual Meeting
Added Value of the Determination of Anti-Ribosomal and Anti-Ku Antibodies for Diagnosis of Systemic Lupus Erythematosus
Johannes Schulte-Pelkum¹, Diana Carmona-Fernandes², Maria Jose Santos², Roger Albesa¹ and Michael Mahler¹, ¹Research, INOVA Diagnostics, San Diego, CA, ²Rheumatology Research Unit Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal
Background/Purpose Anti-dsDNA antibodies (aab) are known as important serological marker to aid in the diagnosis of systemic lupus erythematosus (SLE) and are part of the…
Abstract Number: 1421 • 2014 ACR/ARHP Annual Meeting
Preclinical Interstitial Lung Disease in Early Rheumatoid Arthritis
Javier Narváez¹, Alejandro Robles Perez², Maria Molina Molina³ and Joan Miquel Nolla⁴, ¹Rheumatology, Hospital Universitario de Bellvitge. Barcelona. Spain, Barcelona, Spain, ²Pneumology, Hospital Universitario de Bellvitge, Barcelona, Spain, ³Hospital Universitario de Bellvitge, Barcelona, Spain, ⁴Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain
Background/Purpose: Early detection and treatment of interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA) may ameliorate disease progression. The objective of the present…
Abstract Number: 183 • 2013 ACR/ARHP Annual Meeting
The Performance Of a Point Of Care Test For Detection Of Anti-Mutated Citrullinated Vimentin and Rheumatoid Factor In Early Rheumatoid Arthritis
Preeda Rojanasantikul¹, Prapa Pattrapornpisut², Kulvara Anuruckparadorn³ and Wanruchada Katchamart¹, ¹Division of Rheumatology, Department of Internal Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand, ²Department of Internal Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, ³Department of Transfusion Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
Background/Purpose: Besides rheumatoid factor (RF), anti-cyclic citrullinated peptide antibody (ACPA), a newer serologic marker, was added to the new American College of Rheumatology (ACR)/European League…
Abstract Number: 2553 • 2013 ACR/ARHP Annual Meeting
The Clinical Value Of Testing For Aphl, a New ELISA Kit With a Unique Phospholipid Mixture In Patients With Systemic Lupus Erythematosus (SLE)
Savino Sciascia¹, Giovanni Sanna², Veronica Murru³, Munther A. Khamashta⁴ and Maria Laura Bertolaccini³, ¹Department of Rare, Immunologic, Hematologic and Immunohematologic Diseases, Centro di Immunopatologia e Documentazione su Malattie rare, Torino, Italy, ²Louise Coote Lupus Unit, St. Thomas' Hospital, London, United Kingdom, ³Lupus Research Unit, The Rayne Institute, Kings College London School of Medicine, London, United Kingdom, ⁴Lupus Research Unit, The Rayne Institute, St Thomas Hospital, Kings College London School of Medicine, London, United Kingdom
Background/Purpose: Antibodies directed to APhL (a mixture of phospholipids) have been reported to predict APS more reliably than aCL tests. We designed this study to…
Abstract Number: 2525 • 2013 ACR/ARHP Annual Meeting
An Assay Panel Combining Cell Bound Complement Activation Products With Autoantibodies To Extractable Nuclear Antigens and Mutated Citrullinated Vimentin Helps With The Differential Diagnosis Of Systemic Lupus Erythematosus
Chaim Putterman¹, Richard Furie², R. Ramsey-Goldman³, Anca Askanase⁴, Jill P. Buyon⁵, Kenneth C. Kalunian⁶, W. Winn Chatham⁷, Elena M. Massarotti⁸, Emily C. Somers⁹, Irene Blanco¹⁰, Puja Chitkara¹¹, Nicole Jordan¹², Kyriakos A. Kirou¹³, Arthur Weinstein¹⁴, Susan Manzi¹⁵, Joseph M. Ahearn¹⁶, Claudia Ibarra¹⁷, Derren Barken¹⁸ and Thierry Dervieux¹⁹, ¹Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ²North Shore-LIJ Health System, Lake Success, NY, ³Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴NYU School of Medicine, New York, NY, ⁵Medicine, Division of Rheumatology, NYU School of Medicine, New York, NY, ⁶UCSD School of Medicine, La Jolla, CA, ⁷University of Alabama at Birmingham, Birmingham, AL, ⁸Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁹IntMed, Environmental Health, and OB/GYN, University of Michigan, Ann Arbor, MI, ¹⁰Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ¹¹Rheumatology, SDAMC, San Diego, CA, ¹²Department of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ¹³Hospital for Special Surgery, New York, NY, ¹⁴Washington Hospital Center, Washington, DC, ¹⁵Division of Rheumatology, University of Pittsburgh School of Medicine, Pittsburgh, PA, ¹⁶Lupus Center of Excellence, West Penn Allegheny Health System, Pittsburgh, PA, ¹⁷Clinical Laboratory, Exagen Diagnostics, Vista, CA, ¹⁸Exagen Diagnostics, Vista, CA, ¹⁹Research and Development, Exagen Diagnostics, Vista, CA
Background/Purpose: We previously established the value of cell-bound complement activation products (CBCAPS) in the diagnosis of systemic lupus erythematosus (SLE) (CAPITAL study). The purpose of…
Abstract Number: 2274 • 2013 ACR/ARHP Annual Meeting
Assessment Of The Diagnostic Accuracy Of Different Strategies For Health Fair Case-Finding For Undiagnosed Inflammatory Arthritis
Kaylynn Aiona¹, Christopher C. Striebich², M. Kristen Demoruelle³, Julia J. Rhiannon⁴, Stuart M. Weisman⁵, Marie L. Feser³, Lezlie A. Derber⁵, James H. Goddard⁶, Stacey Brake⁶, Jill Lysengen⁷, Laura Rosseisen⁷, John E. Hokanson¹, Anna E. Baron¹, Jill M. Norris⁸, V. Michael Holers⁹ and Kevin D. Deane³, ¹Colorado School of Public Health, Aurora, CO, ²University of Colorado Denver, Aurora, CO, ³Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁴Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁵University of Colorado School of Medicine, Division of Rheumatology, Aurora, CO, ⁶9Health Fair, Denver, CO, ⁷Arthritis Foundation, Great West Region, Denver Office, Denver, CO, ⁸Epidemiology, Colorado School of Public Health, Aurora, CO, ⁹Rheumatology Division, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Early treatment of inflammatory arthritis (IA), and especially rheumatoid arthritis (RA), leads to improved outcomes, although diagnostic delays may impede timely treatment. We…
Abstract Number: 1891 • 2013 ACR/ARHP Annual Meeting
Proteomic Profile Of Tears: Can It Help To Diagnose Juvenile Arthritis – Associated Uveitis Prior To The Clinical Signs Of Joints Inflammation
Vyacheslav Chasnyk¹, Sergei Nekhai², Alla Hynes³, Tatiana Ammosova⁴, Yuri Obukhov⁴, Ekaterina Gaidar⁵, Anatolyi Kononov⁵, Margarita Dubko⁶, Elena Serogodskaia⁶ and Tatiana Nikitina⁵, ¹Hospital Pediatry, State Pediatric Medical University, Saint-Petersburg, Russia, ²Department of Medicine, Center for Sickle Cell Disease, Howard University, Washington, DC, ³Eye Care Physicians and Surgeons, Winchester, VA, ⁴Howard University, Washington, DC, ⁵Saint-Petersburg State Pediatric Medical University, St. Petersburg, Russia, ⁶State Pediatric Medical University, Saint-Petersburg, Russia
Background/Purpose: Approximately 6% of all cases of uveitis arise in children (Nguyen, Foster, 1998). One of the common causes of uveitis is Juvenile Idiopathic Arthritis…
Abstract Number: 1578 • 2013 ACR/ARHP Annual Meeting
Decreased Sensitivity Of a Commercial Anti-dsDNA Assay In Patients With Moderately To Severely Active Systemic Lupus Erythematosus
Munther A. Khamashta¹, Gabor G. Illei², Stephen Yoo², Liangwei Wang³ and Warren Greth², ¹Lupus Research Unit, The Rayne Institute, St Thomas Hospital, Kings College London School of Medicine, London, United Kingdom, ²Clinical Development, MedImmune, LLC, Gaithersburg, MD, ³Biostatistics, MedImmune, LLC, Gaithersburg, MD
Background/Purpose: Anti-dsDNA autoantibodies are highly specific for SLE. Anti-dsDNA positivity is an important eligibility criterion in many SLE studies, and decreases in anti-dsDNA levels are…
Abstract Number: 1390 • 2013 ACR/ARHP Annual Meeting
Chaperonin Protein 14-3-3n (eta) In Rheumatoid Arthritis and Arthritogenic Viral Infections
Stanley J. Naides, Olga S Zhukov, Rania W Abolhosn and Joanna M Popov, Immunology, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA
Background/Purpose: The 14-3-3 proteins are ubiquitously-expressed intracellular chaperonins. Expression of the η (eta) isoform is restricted to synovial and CNS tissues. Extracellular 14-3-3η induces proinflammatory…

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