Abstracts tagged "Diagnostic Tests"

Abstract Number: 2944 • 2015 ACR/ARHP Annual Meeting
Presepsin (sCD14 subtype) Concentration Is Elevated and Reflects Disease Activity in Systemic Lupus Erythematous Patients
Kohei Tsujimoto¹, Masaaki Fujita², Yutaka Shinkawa², Iku Shirasugi¹, Masashi Taniguchi¹, Saori Hatachi³ and Masato Yagita⁴, ¹Department of Clinical Immunology and Rheumatology, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Japan, ²Department of Clinical Immunology and Rheumatology C, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Japan, ³Department of Rheumatology, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Japan, ⁴Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Japan
Background/Purpose: Presepsin (sCD14 subtype) has recently been identified as a novel biomarker for predicting sepsis. Because presepsin is produced as a consequence of cellular phagocytosis,…
Abstract Number: 1695 • 2014 ACR/ARHP Annual Meeting
Validation of Vesmeter As a Diagnostic Tool of Scleroderma
Yoshihiro Hishitani^1,2, Yoshihito Shima¹, Toshio Tanaka¹ and Atsushi Kumanogoh¹, ¹Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine, Suita, Japan, ²Internal Medicine, Kinki Central Hospital, Itami, Japan
Background/Purpose: Objective method to evaluate the skin involvement in the patients with scleroderma has not been definitely established. We have developed Vesmeter, a computer-linked device…
Abstract Number: 1691 • 2014 ACR/ARHP Annual Meeting
Systemic Sclerosis Patients with Pulmonary Hypertension Have a Lower Change in End Tidal Carbon Dioxide Following Three Minutes of Step Exercise Than Systemic Sclerosis Patients without Pulmonary Hypertension: A Cross-Sectional Study
Elana J. Bernstein¹, Jessica K. Gordon², Robert F. Spiera², Wei-Ti Huang³, Evelyn M. Horn⁴ and Lisa A. Mandl², ¹Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ²Rheumatology, Hospital for Special Surgery, New York, NY, ³Biostatistics, Hospital for Special Surgery, New York, NY, ⁴Cardiology, New York Presbyterian Hospital/Weill Cornell Medical College, New York, NY
Background/Purpose: Pulmonary hypertension (PH) is a leading cause of death in patients with systemic sclerosis (SSc). Transthoracic echocardiogram and pulmonary function testing are standard noninvasive…
Abstract Number: 1629 • 2014 ACR/ARHP Annual Meeting
Added Value of the Determination of Anti-Ribosomal and Anti-Ku Antibodies for Diagnosis of Systemic Lupus Erythematosus
Johannes Schulte-Pelkum¹, Diana Carmona-Fernandes², Maria Jose Santos², Roger Albesa¹ and Michael Mahler¹, ¹Research, INOVA Diagnostics, San Diego, CA, ²Rheumatology Research Unit Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal
Background/Purpose Anti-dsDNA antibodies (aab) are known as important serological marker to aid in the diagnosis of systemic lupus erythematosus (SLE) and are part of the…
Abstract Number: 1421 • 2014 ACR/ARHP Annual Meeting
Preclinical Interstitial Lung Disease in Early Rheumatoid Arthritis
Javier Narváez¹, Alejandro Robles Perez², Maria Molina Molina³ and Joan Miquel Nolla⁴, ¹Rheumatology, Hospital Universitario de Bellvitge. Barcelona. Spain, Barcelona, Spain, ²Pneumology, Hospital Universitario de Bellvitge, Barcelona, Spain, ³Hospital Universitario de Bellvitge, Barcelona, Spain, ⁴Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain
Background/Purpose: Early detection and treatment of interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA) may ameliorate disease progression. The objective of the present…
Abstract Number: 1309 • 2014 ACR/ARHP Annual Meeting
Does Anti-C1q Antibody Have Diagnostic and Prognostic Roles in Childhood – Onset Systemic Lupus Erythematosus?
Thaschawee Arkachaisri¹, Joo Guan Yeo², Justin Hung Tiong Tan³, Sook Fun Hoh⁴, Lena Das³ and Jing Yao Leong², ¹Rheumatology & Immunology, KK Women's and Children's Hospital, Singapore, Singapore, ²Children Intensive Care Unit (CICU), KK Women's and Children's Hospital, Singapore, Singapore, ³Rheumatology and Immunology, KK Women's and Children's Hospital, Singapore, Singapore, ⁴Nursing, KK Women's and Children's Hospital, Singapore, Singapore
Background/Purpose: Biomarkers proven to be effective in aSLE patients may not directly apply to cSLE unless validation is done. Existing evidences have shown immunopathogenic roles…
Abstract Number: 2772 • 2014 ACR/ARHP Annual Meeting
The Use of Imaging in the Diagnosis of Polymyalgia Rheumatica: Systematic Literature Review and Meta-Analysis
Sarah Mackie¹, Gouri Koduri², Catherine L. Hill^3,4, Andrew Hutchings⁵, Richard J. Wakefield⁶, Bhaskar Dasgupta⁷ and Jeremy Wyatt⁸, ¹NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, ²Rheumatology, York Teaching Hospital NHS Foundation Trust, York, United Kingdom, ³Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, Australia, ⁴Discipline of Medicine, University of Adelaide, Adelaide, Australia, ⁵Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom, ⁶NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁷Department of Rheumatology, Southend University Hospital, Essex, United Kingdom, ⁸Leeds Insitute of Health Sciences, University of Leeds, Leeds, United Kingdom
Background/Purpose ACR/EULAR provisional classification criteria for polymyalgia rheumatica (PMR) incorporate musculoskeletal ultrasound of shoulder and hip (bursitis and synovitis given equal weight). Our objective was…
Abstract Number: 1308 • 2014 ACR/ARHP Annual Meeting
Antinucleosome Antibodies As Potential Diagnostic and Prognostic Biomarkers in Childhood Onset Systemic Lupus Erythematosus
Thaschawee Arkachaisri¹, Joo Guan Yeo², Justin Hung Tiong Tan³, Sook Fun Hoh⁴, Lena Das³ and Jing Yao Leong², ¹Rheumatology & Immunology, KK Women's and Children's Hospital, Singapore, Singapore, ²Children Intensive Care Unit (CICU), KK Women's and Children's Hospital, Singapore, Singapore, ³Rheumatology and Immunology, KK Women's and Children's Hospital, Singapore, Singapore, ⁴Nursing, KK Women's and Children's Hospital, Singapore, Singapore
Background/Purpose: The role of antinucleosome antibodies (ANuA) in the immunopathogenesis of SLE is evident. ANuA was shown to be a good, if not better than…
Abstract Number: 2588 • 2014 ACR/ARHP Annual Meeting
Which Characteristics of Inflammatory Back Pain (CBP) Forecast the Presence of HLA-B27? Results from the Esperanza Cohort
Victoria Navarro-Compán¹, Juan Jose Aznar², Luis F Linares³, Eduardo Collantes-Estévez⁴, Robert B. M. Landewé⁵, Désirée van der Heijde⁶ and Pedro Zarco⁷, ¹Rheumatology, University Hospital La Paz and Leiden University Medical Center, Madrid, Spain, ²Hospital de Mérida, Mérida (Badajoz), Spain, ³University Hospital Virgen de la Arrixaca, Murcia, Spain, ⁴IMIBIC/University Hospital Reina Sofía, Córdoba, Spain, Córdoba, Spain, ⁵Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, ⁶Leiden University Medical Center, Leiden, Netherlands, ⁷Rheumatology Department, Fundación Hospital Alcorcon, Alcorcon, Madrid, Spain
Background/Purpose: CBP is often the starting point for a suspicion of axSpA. In the ASAS-criteria for axial SpA either MRI of the SI-joints or HLA-B27-testing…
Abstract Number: 1258 • 2014 ACR/ARHP Annual Meeting
Enzyme-Linked Immunosorbent Assays for Detection of Anti-Transcriptional Intermediary Factor-1 Gamma and Anti-Mi-2 Autoantibodies in Dermatomyositis: Utility and Crossreactivity
Manabu Fujimoto¹, Akihiro Murakami², Shunsuke Kurei², Akiko Kuwajima³, Yasuhiro Fujisawa¹, Atsushi Kawakami⁴, Michiaki Mishima⁵, Shinji Sato⁶, Mariko Seishima⁷, Takafumi Suda⁸, Tsuneyo Mimori⁹, Kazuhiko Takehara¹⁰ and Masataka Kuwana¹¹, ¹Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ²Medical & Biological Laboratories Co., Ltd, Nagaya, Japan, ³Medical & Biological Laboratories Co.,Ltd., Nagoya, Japan, ⁴Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁵Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan, Kyoto, Japan, ⁶Division of Rheumatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan, ⁷Department of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan, ⁸Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan, ⁹Dept of Rheum & Clinical Immunology, Kyoto Univ Grad Schl of Med, Kyoto, Japan, ¹⁰Dermatology, Kanazawa University, Kanazawa, Japan, ¹¹Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
Background/Purpose Anti-transcriptional intermediary factor 1 (TIF-1) and anti-Mi-2 antibodies (Abs) are myositis-specific autoantibodies (MSA) selectively detected in dernatomyositis (DM) patients. Anti-TIF-1 Ab is frequently found…
Abstract Number: 2586 • 2014 ACR/ARHP Annual Meeting
Which Characteristics of Inflammatory Back Pain (CBP) Forecast the Presence of Sacroiliitis on Magnetic Resonance Imaging (MRI)? Results from the Esperanza Cohort
Victoria Navarro-Compán¹, Raquel Almodóvar González², Azucena Hernández³, Emma Beltrán⁴, Eugenio De Miguel⁵, Robert B. M. Landewé⁶, Désirée van der Heijde⁷ and Pedro Zarco⁸, ¹Rheumatology, University Hospital La Paz and Leiden University Medical Center, Madrid, Spain, ²Rheumatology Unit, Hospital Universitario Fundación Alcorcón, Madrid, Spain, ³Rheumatology, Hospital Virgen de la Salud, Toledo, Spain, ⁴University General Hospital of Valencia, Valencia, Spain, ⁵Rheumatology, University Hospital La Paz - IdiPaz, Madrid, Spain, ⁶Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, ⁷Leiden University Medical Center, Leiden, Netherlands, ⁸Rheumatology Department, Fundación Hospital Alcorcon, Alcorcon, Madrid, Spain
Background/Purpose: CBP is often the starting point for a suspicion of axSpA. In the ASAS-criteria for axial SpA either MRI of the SI-joints or HLA-B27-testing…
Abstract Number: 400 • 2014 ACR/ARHP Annual Meeting
Clinical Utility of 14-3-3η in the Evaluation of Inflammatory Arthritis
Lance Feller¹, Paul Tuttle IV² and Terry L. Moore³, ¹Rheumatology, Saint Louis University, St. Louis, MO, ²Rheumatology, Saint Louis University, Saint Louis, MO, ³Internal Medicine/Rheumatology, Saint Louis University, Saint Louis, MO
Background/Purpose 14-3-3 proteins are chaperonins found in all eukaryotic cells. There are multiple isoforms which are thought to be involved in intracellular signaling and transcription…
Abstract Number: 2534 • 2014 ACR/ARHP Annual Meeting
Ocular Surface Temperature in Early Sjogren’s Syndrome and Established Disease
Andreea Coca¹, Ranjini Kottaiyan², Mircea Coca³, Debbie Campbell⁴, Holly Hindman² and James Aquavella², ¹Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ²Ophtalmology, University of Rochester, Rochester, NY, ³Ophtalmology, University of Texas Medical Branch, Galveston, TX, ⁴Allergy, Immunology and Rheumatology, Univerity of Rochester, Rochester, NY
Background/Purpose Due to a variety of factors it is challenging to make a definite diagnosis in the early stages of Sjögren’s syndrome (SS). The ocular…
Abstract Number: 357 • 2014 ACR/ARHP Annual Meeting
Development and Validation of a Diagnostic Bead-Based Multiplex Autoantibody Assay:Screening for Autoantibodies to Detect “Seronegative” Rheumatoid Arthritis
Stefan Vordenbäumen¹, Angelika Lueking², Carmen Theek², Ralph Brinks¹, Rebecca Fischer-Betz¹, Jutta Richter¹, Ellen Bleck¹, Jacqueline Detert³, Gerd Burmester⁴, Peter Schulz-Knappe² and Matthias Schneider¹, ¹Rheumatology, Heinrich-Heine-University, Düsseldorf, Germany, ²Protagen AG, Dortmund, Germany, ³Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Berlin, Germany, ⁴Departement of Rhe, University Medicine, Berlin, Germany
Background/Purpose: Autoantibodies (auto-Ab) against citrullinated peptides (ACPA) and rheumatoid factor (RF) are important biomarkers in the diagnostic process of rheumatoid arthritis (RA). However, RF or…
Abstract Number: 2540 • 2014 ACR/ARHP Annual Meeting
Sjö™, an Advanced Diagnostic Panel for Detection of Sjögren’s Syndrome Autoantibodies
Mark Jasek¹, Kishore Malyavantham², Lakshmanan Suresh³, Julian Ambrus⁴ and Dennis Pardo⁵, ¹Medical and Scientific Affairs, Nicox Inc, Fort Worth, TX, ²Office of Science & Technology, IMMCO Diagnostics Inc., Amherst, NY, ³60 Pineview Drive, State University of New York/Buffalo, Buffalo, NY, ⁴Division of Allergy, Immunology and Rheumatology, Department of Medicine, State University of New York at Buffalo, Buffalo, NY, ⁵Professional Affairs, Nicox Inc, Fort Worth, TX
Background/Purpose Sjögren’s syndrome (SS) is a complex autoimmune disease involving the salivary and lacrimal glands along with various systemic manifestations. It is a difficult disease to…

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