ACR Meeting Abstracts

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Abstracts tagged "diagnosis"

  • Abstract Number: 407 • 2014 ACR/ARHP Annual Meeting

    Serum 14-3-3η Protein Supplements Traditional Rheumatoid Arthritis Biomarkers

    Olga Zhukov1, Jonnielyn Rivera1, Charles M. Rowland2, Joanna M. Popov1 and Stanley J. Naides3, 1Immunology, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, 2Bioinformatics, Celera, Alameda, CA, 3Immunology, Quest Diagnostics, San Juan Capistrano, CA

    Background/Purpose: The 14-3-3 family of chaperonin proteins consists of 7 isomers.  The tissue distribution of the 14-3-3η (eta) isoform is limited to synovial tissue and…
  • Abstract Number: 284 • 2014 ACR/ARHP Annual Meeting

    Single Hub and Access Point for Paediatric Rheumatology in Europe (SHARE)– Evidence Based Recommendations for Diagnosis and Treatment of Juvenile Idiopathic Arthritis

    S.J. Vastert1, Victor Boom2, Jordi Anton3, Tamás Constantin4, Pavla Dolezalova5, Gerd Horneff6, Pekka Lahdenne7, Bo Magnusson8, Kirsten Minden9, K. Nistala10, Pierre Quartier11, Ingrida Rumba-Rozenfelde12, Nicolino Ruperto13, Vanessa Remy Piccolo14, Ricardo A. G. Russo15, Yosef Uziel16, Carine Wouters17, Alberto Martini18, Angelo Ravelli19, Helen Foster20 and Nico Wulffraat21, 1Pediatric Rheumatology, University Medical Center Utrecht, Utrecht, Netherlands, 2Paediatric Rheumatology, University Medical Center Utrecht, Utrecht, Netherlands, 3Pediatric Rheumatology Unit. Hospital Sant Joan de Déu. Universitat de Barcelona, Barcelona, Spain, 4Pediatric Rheumatology, University Childrens Hospital, Budapest, Hungary, 5Paediatric Rheumatiology unit, 1st Faculty of Medicine, General University Hospital, Prague, Czech Republic, 6Asklepios Klinik Sankt Augustin, Sankt Augustin, Germany, 7Paediatrics, Helsinki University Central Hospital, Helsinki, Finland, 8Pediatric Rheumatology, Astrid Lindgren Children's Hospital, Stockholm, Sweden, 9Epidemiology unit, German Rheumatism Research Center, Berlin, Germany, 10Centre for Rheumatology, University College London, London, United Kingdom, 11Pediatric Rheumatology, IMAGINE Institute, Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Université Paris-Descartes, Paris, France, 12University of Latvia, Riga, Latvia, 13Pediatria II,, Istituto Giannina Gaslini, Genoa, Italy, 14Pediatric Rheumatology, Hopital Necker Enfants Malades, Paris, France, 15Immunology & Rheumatology, Hospital de Pediatria Garrahan, Buenos Aires, Argentina, 16Tel-Aviv University, Sackler School of Medicine, Tel-Aviv, Israel, 17University of Leuven, Laboratory of Pediatric Immunology, University Hospital Leuven, Leuven, Belgium, 18Istituto Giannina Gaslini, Genova, Italy, 19University of Genova, Genova, Italy, 20Newcastle University, Newcastle, United Kingdom, 21Paediatric Immunology and Rheumatology, University Medical Center Utrecht, Utrecht, Netherlands

    Background/Purpose Juvenile Idiopathic Arthritis (JIA) is one of the most common chronic pediatric rheumatic diseases (PRD). As is the case for most PRD's, evidence-based guidelines…
  • Abstract Number: 256 • 2014 ACR/ARHP Annual Meeting

    Characteristics of Pain in Fabry Disease

    Olivier Lidove1, Esther Noel2, Eric Hachulla3, Francis Gaches4, Claire Douillard5, Bernadette Darne6, Kim Heang Ly7, Christian Lavigne8, Agathe Masseau9, Laurent Aaron10, Boris Bienvenu11, Thierry Zenone12, Philippe Vitielli6, Vanessa Leguy-Seguin13 and Jean Marc Ziza14, 1Médecine interne, Hôpital Croix-Saint-Simon, PARIS, France, 2CHU de Strasbourg - Hopital Civil, Strasbourg, France, 3Faculté de Médecine Henri Warembourg, Université Lille Nord de France, Lille, France, 4Hopital Joseph Ducuing, Toulouse, France, 5CHU Lille, Lille, France, 6Monitoring Force, Maisons-Laffitte, France, 7CHU Dupuytren, Limoges, Limoges, France, 8CHU d'Angers, Angers, France, 9Internal Medicine Department, Nantes University Hospital, Nantes, France, 10Internal Medicine, Hôpital Jacques Coeur, Bourges, Bourges, France, 11Médecine interne, CHU Côte de Nacre, CAEN, France, 12CH de Valence, Valence, France, 13CHU Dijon, Dijon, France, 14Hopital Croix-Saint-Simon, Paris Cedex 20, France

    Background/Purpose Fabry disease (FD) is an X-linked disorder caused by a deficiency of lysosomal alpha-galactosidase A resulting in accumulation of glycosphingolipids. Clinical manifestations include a…
  • Abstract Number: 202 • 2014 ACR/ARHP Annual Meeting

    Is Schuss View Alone Enough for the Diagnosis of Femorotibial Osteoarthritis ? the Khoala Cohort Study

    Christian Roux1, Bernard Mazieres2, Evelyne Verrouil2, Anne-Christine Rat,3, Patrice Fardellone4, Bruno Fautrel5, Jacques Pouchot6, Alain Saraux7, Francis Guillemin8, Liana Euller Ziegler9 and Joel Coste10, 1Rhumatologie, Hopital Archet 1 - Université Nice Sophia Antipolis, Nice, France, 2CHU Toulouse, Toulouse, France, 3Université de Lorraine, Université Paris Descartes, Apemac, EA 4360, Nancy, France, 4Service de Rhumatologie, Hôpital Nord, C.H.U. d'Amiens, Amiens, France, 5CHU - Hôpital Pitié-Salpêtrière, Paris, France, 6Medecine Interne, Hopital Louis Mourier, Colombes, FRANCE, France, 7Rheumatology, CHU de la Cavale Blanche and Université Bretagne occidentale, Brest Cedex, France, 8INSERM, Centre d'Investigation Clinique - Epidémiologie Clinique (CIC-EC) CIE6, Nancy, France, 9151 rte de St Antoine de Gines, CHU de Nice -Université Nice Sophia Antipolis, Nice, France, 10CHU Hotel Dieu, Paris, France

    Background/Purpose: Associating an anteroposterior (AP) extended-knee X-ray with a semiflexed AP or posteroanterior (PA) view is considered the gold standard for radiologically diagnosing tibiofemoral osteoarthritis…
  • Abstract Number: L13 • 2013 ACR/ARHP Annual Meeting

    Serum 14-3-3η Marks RA Development in Arthralgia and Radiographic Progression in Early RA Patients

    D. van Schaardenburg1, Marian van Beers-Tas2, Karin Britsemmer2, Mairead Murphy3, Walter P. Maksymowych4, Maarten Boers5 and Anthony Marotta6, 1Jan van Breemen Research Institute, Amsterdam, Netherlands, 2Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, 3Augurex Life Sciences Corp., North Vancouver, BC, Canada, 4Department of Medicine, University of Alberta, Edmonton, AB, Canada, 5Deapartment of Epidemiology and Biostatistics, Jan van Breemen Research Institute/Reade, Amsterdam, Netherlands, 6Augurex Life Sciences Corp, North Vancouver, BC, Canada

    Background/Purpose: The focus of RA management is increasingly towards early detection and treatment. While newly-diagnosed patients will benefit from treatment decisions based on more robust…
  • Abstract Number: 2756 • 2013 ACR/ARHP Annual Meeting

    Serum Periostin Is Associated With Prevalent Knee Osteoarthritis and Predicts Disease Progression In Women: The Ofely Study

    Jean-Charles Rousseau1, Elisabeth Sornay-Rendu1, Cindy Bertholon1, Patrick Garnero2 and Roland Chapurlat3, 1INSERM UMR 1033, Lyon, France, 2INSERM, UMR 1033, Lyon and Cisbio Bioassays, Bagnols/Cèze, France, 3Service de Rhumatologie et Pathologie Osseuse, INSERM UMR 1033 and Université de Lyon, Hôpital Edouard Herriot, Lyon, France

    Background/Purpose: Periostin (POSTN) is a secreted vitamin K-dependent (Gla-containing) protein produced by osteoblasts and chondrocytes. The aim of this study was to investigate the relationships…
  • Abstract Number: 2584 • 2013 ACR/ARHP Annual Meeting

    Screening and Diagnostic Modalities For Systemic Sclerosis-Associated Pulmonary Arterial Hypertension: A Systematic Review

    Heather Gladue1, Nezam I. Altorok2, Whitney Townsend1, Vallerie McLaughlin3 and Dinesh Khanna4, 1University of Michigan, Ann Arbor, MI, 2Internal Medicine and Rheumatology, University of Michigan, Ann Arbor, MI, 3Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 4Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI

    Background/Purpose: Pulmonary arterial hypertension (PAH) affects patients with connective tissue diseases (CTD), especially systemic sclerosis (SSc) and MCTD. Despite this, there continues to be delay…
  • Abstract Number: 2585 • 2013 ACR/ARHP Annual Meeting

    Left Ventricular Dysfunction Reflected By Higher Serum Brain Natriuretic Peptide Accounts For Poorer Prognosis Of Pulmonary Arterial Hypertension Associated With Systemic Sclerosis

    Sumiaki Tanaka1, Yoshiyuki Arinuma1, Tatsuhiko Wada1, Tatsuo Nagai2, Jun Okada3 and Shunsei Hirohata1, 1Int Med/Rheumatol & Infec Dis, Kitasato University School of Medicine, Sagamihara, Japan, 2Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Sagamihara, Japan, 3Nutritional management, Kitasato Junior Collage of health and Hygienic Sciences, Minami-Uonuma, Japan

    Background/Purpose: Recentry, development of potent effective newer drugs for pulmonary arterial hypertension (PAH) have resulted in improving survival of the patients.  However, the prognosis of…
  • Abstract Number: 2519 • 2013 ACR/ARHP Annual Meeting

    A Systemic Lupus Erythematosus (SLE) Diagnostic Test Based On DNA Methylation Signatures From Peripheral Blood Mononuclear Cells

    David W. Anderson1, Robert Shoemaker2, Kurt Krummel3, Zachary Hornby4 and Jonathan E. Lim1, 1Research and Development, IGNYTA, Inc., San Diego, CA, 2Bioinformatics, IGNYTA, Inc., San Diego, CA, 3Research and Development-Assay Development, IGNYTA, Inc., San Diego, CA, 4Business Development, IGNYTA, Inc., San Diego, CA

    Background/Purpose: The heterogeneous nature of SLE and a lack of reliable biomarkers make SLE a challenge to classify in patients. A differential diagnosis of SLE…
  • Abstract Number: 2288 • 2013 ACR/ARHP Annual Meeting

    Novel Biomarkers From Peripheral Blood Mononuclear Cells Indicate Disease Activity In Rheumatoid Arthritis Patients

    Jason Ptacek1, Rachael Hawtin2, Brent Louie1, Erik Evensen1, James Cordeiro1, Barbara Mittleman1, Michelle Atallah1, Alessandra Cesano2, Clifton O. Bingham III3, Stacey Cofield4, Jeffrey R. Curtis5, Maria I. Danila4, Richard A. Furie6, MC Genovese7, Marc C. Levesque8, Larry W. Moreland8, Peter A. Nigrovic9, James R. O'Dell10, William H. Robinson11, Nancy A. Shadick9, E. William St Clair12, Christopher C. Striebich13, Geoffrey M Thiele14, Peter K. Gregersen6 and S. Louis Bridges Jr.4, 1Nodality, Inc., South San Francisco, CA, 2Nodality Inc., South San Francisco, CA, 3Rheumatology, Johns Hopkins University, Baltimore, MD, 4University of Alabama at Birmingham, Birmingham, AL, 5Epidemiology, University of Alabama at Birmingham, School of Public Health, Birmingham, AL, 6The Feinstein Institute for Medical Research and North Shore-Long Island Jewish Health System, Lake Success, NY, 7Stanford University, Palo Alto, CA, 8University of Pittsburgh, Pittsburgh, PA, 9Brigham and Women's Hospital/Harvard University, Cambridge, MA, 10Veteran Affairs Nebraska Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, 11VA Palo Alto Health Care System and Stanford University, Palo Alto, CA, 12Medicine, Duke Unversity Medical Center, Durham, NC, 13University of Colorado Denver, Aurora, CO, 14Omaha VA and the University of Nebraska Medical Center, Omaha, NE

    Background/Purpose:   Biomarkers reflecting immune function and associating with disease activity can help stratify rheumatoid arthritis (RA) patients (pts) in practice and in clinical trials.…
  • Abstract Number: 2160 • 2013 ACR/ARHP Annual Meeting

    The Journey to Diagnosis in As/Axial Spondyloarthritis – the Psychological Impact of Delay

    Jane Martindale1,2 and Lynne Goodacre2, 1Physiotherapy, Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, United Kingdom, 2Faculty of Health and Medicine, Lancaster University, Lancaster, United Kingdom

    Background/Purpose: It is not uncommon for 8 to 11 years to pass between symptoms onset and definitive diagnosis of AS/axial SpA (Gran 1997, Feldtkeller, 2003).…
  • Abstract Number: 2025 • 2013 ACR/ARHP Annual Meeting

    Distinctive Expression Profiles Of Long Intergenic Non-Coding RNA Between Polymyalgia Rheumatica and Rheumatoid Arthritis Might Contains Helpful Suggestions For Understanding and Discriminating These Diseases

    Yoshinobu Koyama1, Motohiko Tanino2, Hirokazu Shiraishi3, Shuji Nagano4, Toshiyuki Ota4 and Toshie Higuchi5, 1Division of Rheumatology, Okayama Red Cross General Hospital, Okayama, Japan, 2DNA Chip Research Inc., Yokohama, Japan, 3Orthopedics, Iizuka Hospital, Iizuka, Japan, 4Center for Rheumatic Diseases, Iizuka Hospital, Iizuka, Japan, 5Center for Autoimmune Diseases, Division of Rheumatology, Japan Red Cross Okayama Hospital, Okayama, Japan

    Background/Purpose: There are many clinical similarities between polymyalgia rheumatica (PMR) and rheumatoid arthritis (RA). It has been reported that the specificity for discriminating PMR from…
  • Abstract Number: 838 • 2013 ACR/ARHP Annual Meeting

    Recommendations for the Classification and Diagnosis of Fibromyalgia Syndrome Provided By Independently Developed Evidence-Based Interdisciplinary Guidelines Spanning Three Continents

    Mary-Ann Fitzcharles1, Yoram Shir2, Jacob N. Ablin3, Dan Buskila4, Howard Amital5, Peter Henningsen6 and Winfried Häuser7, 1Rheumatology & Alan Edwards Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada, 2Alan Edwards Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada, 3Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 4Ben-Gurion University, Beer-Sheva, Israel, 5Department of Medicine B, Center for Autoimmune Diseases, Sheba Medical Center, Tel-hashomer, Israel, 6Department Internal Medicine I, Klinikum Saarbrücken, Saarbrücken, Germany, 7Klinikum Saarbrücken, Saarbrücken, Germany

    Background/Purpose: Fibromyalgia (FM), often disputed and challenged, has emerged as a clear cluster of symptoms and co-morbidities, characterized by subjective complaints without physical or biomarker…
  • Abstract Number: 826 • 2013 ACR/ARHP Annual Meeting

    The Value Of History and Physical Examination Findings In The Diagnosis Of Symptomatic Meniscal Tear Among Middle-Age Subjects With Knee Pain

    Jeffrey N. Katz1, Yan Dong2, John Wright3, Stephanie Chen4, Scott Martin5, Laurel Donnell-Fink5, Benjamin N. Rome2 and Elena Losina2, 1Rheumatology and Orthopedics, Brigham and Women's Hospital, Boston, MA, 2Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, 3Orthopedic Surgery, Brigham and Women's Hospital, Boston, MA, 4Orthopedics and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, 5Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Clinicians often rely on mechanical symptoms (e.g. clicking, catching, popping, giving way) and tests such as the McMurray sign in the diagnosis of symptomatic…
  • Abstract Number: 690 • 2013 ACR/ARHP Annual Meeting

    Assessment Of The New American and European Classification Criteria For Systemic Sclerosis In The Norwegian Systemic Connective Tissue Disease and Vasculitis Registry

    Anna-Maria Hoffmann-Vold1, Torhild Garen2, Oyvind Midtvedt1 and Øyvind Molberg3, 1Rheumatology, Oslo University Hospital, Oslo, Norway, 2Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, 3Oslo University Hospital, Oslo, Norway

    Background/Purpose: To assess the newly established ACR/EULAR classification criteria for systemic sclerosis 1 (SSc) in a large Norwegian SSc registry cohort. Methods: The Norwegian systemic…
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