Abstracts tagged "diagnosis"

Abstract Number: 2441 • 2015 ACR/ARHP Annual Meeting
Serum 14-3-3η Is Present in JIA and Is Not Associated with RF+ Polyarthritis
Alan M. Rosenberg¹, Walter Maksymowych², Yuan Gui³ and Anthony Marotta³, ¹Department of Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, ²Department of Medicine, University of Alberta, Edmonton, AB, Canada, ³Augurex Life Sciences Corp., Vancouver, BC, Canada
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is a collective term used to denote clinically discrete subtypes, which include: Enthesitis-related arthritis, Oligoarthritis, Polyarthritis, Psoriatic arthritis, Systemic arthritis…
Abstract Number: 2443 • 2015 ACR/ARHP Annual Meeting
Pediatric Tele-Rheumatology: A Pilot Project to Assess Accuracy of Physical Examination Findings and Diagnostic Concordance at a Distance
Michael Henrickson¹, Jody Raugh², Kelsey Hofacer³ and Adam Furnier⁴, ¹Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Occupational and Physical Therapy, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Center for Telehealth, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Quality Improvement Systems, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Telemedicine (TM) offers a strategic means of extending limited clinical pediatric rheumatology (PR) workforce capacity to improve access to care for patients in remote…
Abstract Number: 2453 • 2015 ACR/ARHP Annual Meeting
Evidence-Based Decision Support for Pediatric Rheumatology Reduces Diagnostic Errors, with the Potential to Reduce Capacity Shortage
Balu Athreya¹, Mary Beth Son², Jonathan S. Hausmann³, Elizabeth Ang⁴, David Zurakowski⁵, Michael Segal⁶ and Robert Sundel⁷, ¹duPont Hospital for Children/Thomas Jefferson University, Wilmington, DE, ²Division of Immunology, Children's Hospital Boston, Boston, MA, ³Rheumatology, Children's Hospital Boston, Boston, MA, ⁴Paediatrics, University Children's Medical Institute, NUH, Singapore, Singapore, ⁵Departments of Anesthesia and Surgery, Boston Children’s Hospital, Boston, MA, ⁶SimulConsult, Chestnut Hill, MA, ⁷Immunology, Childrens Hospital, Boston, MA
Background/Purpose: This projects seeks to respond to the critical shortage of pediatric rheumatologists encapsulating the diagnostic information of the field in an advanced diagnostic decision…
Abstract Number: 2585 • 2015 ACR/ARHP Annual Meeting
Serum 14-3-3η Is an RA Specific Mechanistic Marker
Bidisha Dasgupta¹, Yauheniya Cherkas¹, Sarah Lamberth¹, Karen Hayden¹, Carrie Brodmerkel¹, Anthony Marotta² and Mark Curran¹, ¹Janssen Research & Development, LLC., Spring House, PA, ²Augurex Life Sciences Corp., Vancouver, BC, Canada
Background/Purpose: 14-3-3η is an emerging soluble Rheumatoid Arthritis (RA) biomarker that activates intracellular pathways that lead to the upregulation of inflammatory and joint damage factors.…
Abstract Number: 185 • 2015 ACR/ARHP Annual Meeting
Success Rate and Utility of Ultrasound Guided Synovial Biopsies in Clinical Practice
Aurélie Najm, Benoît Le Goff and Yves Maugars, Rheumatology, Rheumatology, Nantes, France
Background/Purpose: Histological and bacteriological analysis of synovial tissue (ST) can be useful in the diagnosis of arthritis of undetermined origin. Ultrasound can assist this biopsy…
Abstract Number: 2587 • 2015 ACR/ARHP Annual Meeting
CRP and 14-3-3η Are Each Associated with Joint Damage Progression, Their Titres Do Not Correlate and Are Better Predictors of Progression Together Than Alone
Gilles Boire^1,2, Nathalie Carrier³, Artur de Brum-Fernandes^1,4, Patrick Liang^1,4, Ariel Masetto^2,5, Yuan Gui⁶, Jane Savill⁶, Sara Michienzi⁶, Henri Ménard⁷, Walter Maksymowych⁸ and Anthony Marotta⁶, ¹Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada, ²Department of Medicine/Division of Rheumatology, University of Sherbrooke, Sherbrooke, QC, Canada, ³Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁴Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁵Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada, ⁶Augurex Life Sciences Corp., Vancouver, BC, Canada, ⁷MSK Research Axis, McGill University Health Center Research Institute, Montreal, QC, Canada, ⁸Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: As a marker of inflammation and an acute phase reactant, C-reactive protein (CRP) is routinely used in clinical practice and in RA classification criteria.…
Abstract Number: 240 • 2015 ACR/ARHP Annual Meeting
Volumetric Assessment of Tophaceous Gout
Ralf G. Thiele¹, Laura Coates² and Darren Tabechian¹, ¹University of Rochester Medical Center, Rochester, NY, ²Medicine, University of Rochester, Rochester, NY
Background/Purpose: Ultrasound (US) can identify monosodium urate (MSU) tophi within joints, tendons, bursae and other soft tissues. The ability to readily, quickly and inexpensively assess…
Abstract Number: 2660 • 2015 ACR/ARHP Annual Meeting
Elevated 14-3-3η Serum Protein Levels Increase RA Confirmation Rates in Recent-Onset Polyarthritis Patients
Nathalie Carrier¹, Anthony Marotta², Artur de Brum-Fernandes^3,4, Patrick Liang^3,4, Ariel Masetto^5,6, Yuan Gui², Jane Savill², Sara Michienzi², Henri Ménard⁷, Walter Maksymowych⁸ and Gilles Boire⁴, ¹Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, ²Augurex Life Sciences Corp., Vancouver, BC, Canada, ³Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁴Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada, ⁵Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada, ⁶Department of Medicine/Division of Rheumatology, University of Sherbrooke, Sherbrooke, QC, Canada, ⁷MSK Research Axis, McGill University Health Center Research Institute, Montreal, QC, Canada, ⁸Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: The 14-3-3 family of conserved regulatory proteins consists of seven isoforms: α/β, γ, δ/ζ, ε, η, θ/τ and σ. These proteins exist as intracellular…
Abstract Number: 509 • 2015 ACR/ARHP Annual Meeting
In Early Undifferentiated Polyarthritis, 14-3-3η Seroreversion or Sustained Negativity Is Associated with Better Radiographic Outcomes, Even in DAS-28 Remitters
Gilles Boire^1,2, Nathalie Carrier³, Artur de Brum-Fernandes^1,4, Patrick Liang^1,4, Ariel Masetto^2,5, Yuan Gui⁶, Jane Savill⁶, Sara Michienzi⁶, Henri Ménard⁷, Walter Maksymowych⁸ and Anthony Marotta⁶, ¹Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada, ²Department of Medicine/Division of Rheumatology, University of Sherbrooke, Sherbrooke, QC, Canada, ³Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁴Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁵Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada, ⁶Augurex Life Sciences Corp., Vancouver, BC, Canada, ⁷MSK Research Axis, McGill University Health Center Research Institute, Montreal, QC, Canada, ⁸Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Advancements in RA treatment approaches with DMARDs and biological agents have enabled disease remission goals that were previously considered unattainable. The concept of "tight…
Abstract Number: 3083 • 2015 ACR/ARHP Annual Meeting
Antibody Array Based Proteomic Screening of 274 Serum Markers in Systemic Lupus Erythematosus
Tianfu Wu¹, Huihua Ding², Cristina Arriens³, Chungwen Wei⁴, Jennifer H. Anolik⁵, David R. Karp³, Nancy J. Olsen⁶, Michelle Petri⁷, Ignacio Sanz⁴, Ramesh Saxena⁸ and Chandra Mohan², ¹Department of Biomedical Engineering, University of Houston, Houston, TX, ²Biomedical Engineering, University of Houston, Houston, TX, ³Internal Medicine - Rheumatic Diseases, University of Texas Southwestern Medical Center, Dallas, TX, ⁴Rheumatology, Emory University, Atlanta, GA, ⁵University of Rochester Medical Center, Rochester, NY, ⁶Divsion of Rheumatology, Department of Medicine, Penn State MS Hershey Medical Center, Hershey, PA, ⁷Rheumatology, Johns Hopkins University Hospital, Baltimore, MD, ⁸Nephrology, University of Texas Southwestern Medical Center, Dallas, TX
Background/Purpose: Given that early detection of renal involvement in systemic lupus erythematosus (SLE) and prompt management of the disease can have a significant impact on…
Abstract Number: 621 • 2015 ACR/ARHP Annual Meeting
Previous Diagnosis of Sjögren’s Syndrome As Rheumatoid Arthritis or Systemic Lupus Erythematosus
Astrid Rasmussen¹, Lida Radfar², Kiely Grundahl³, David M. Lewis⁴, Donald U Stone^5,6, C. Erick Kaufman⁷, Daniel J Wallace⁸, Michael H. Weisman⁹, Swamy Venuturupalli¹⁰, Christopher J Lessard¹¹, Biji Kurien¹², Juan-Manuel Anaya¹³, Michael D. Rohrer¹⁴, Raj Gopalakrishnan¹⁵, Glen D Houston¹⁶, James Chodosh¹⁷, Pamela J Hughes¹⁸, Nelson L. Rhodus¹⁹, John Ice¹, Kimberly Hefner²⁰, Jennifer A. Kelly²¹, Kathy L. Sivils¹ and R. Hal Scofield^1,22,23, ¹Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Oral Diagnosis and Radiology Department, University of Oklahoma Health Sciences Center College of Dentistry, Oklahoma City, OK, ³Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma CIty, OK, ⁴College of Dentistry, Department of Oral and Maxillofacial Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁵Department of Ophthalmology, Johns Hopkins University, Riyadh, Saudi Arabia, ⁶Research Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia, ⁷College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁸Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁹Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ¹⁰Cedars-Sinai Medical Center, West Hollywood, CA, ¹¹Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ¹²Arthritis and Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ¹³Center for Autoimmune Diseases Research (CREA), Universidad del Rosario., Bogota, Colombia, ¹⁴Hard Tissue Research Laboratory, University of Minnesota School of Dentistry, Minneapolis, MN, ¹⁵Diagnostic and Biological Sciences, Division of Oral Pathology, University of Minnesota, Minneapolis, MN, ¹⁶Heartland Pathology, Oklahoma City, OK, ¹⁷Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, ¹⁸Division of Oral and Maxillofacial Surgery, University of Minnesota, Minneapolis, MN, ¹⁹Department of Oral Surgery, University of Minnesota School of Dentistry, Minneapolis, MN, ²⁰Hefner Eye Care and Optical Center, Oklahoma City, OK, ²¹Arthritis & Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²²Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ²³US Department of Veterans Affairs Medical Center, Oklahoma City, OK
Background/Purpose: The diagnosis of Sjögren′s Syndrome (SS) is often difficult and many patients are symptomatic for years with other diagnoses before confirmation of SS. Overlapping…
Abstract Number: 664 • 2015 ACR/ARHP Annual Meeting
Patient Reported Outcomes and Assessment of the Quality of Life in a Cohort of Patients Affected By Enteropathic Spondyloarthritis: Definitive Results of a Monocentric Prospective Observational Study at One Year
Chiara Avellini¹, Laura Bolognini², Alessia Farinelli¹, Monia Ciferri³, Greta Gambacorta³, Devis Benfaremo³, Serena Cedraro³, Matteo Rossini³, William Capeci³, Lucia Manfredi³, Laura Postacchini³, Giammarco Fava², Piergiorgio Mosca², Giovanni Pomponio³, Michele Maria Luchetti³ and Armando Gabrielli³, ¹Scienze Cliniche e Molecolari, Clinica Medica, Università Politecnica delle Marche, Ancona, Italy, ²Gastroenterologia, Azienda "Umberto I-G.M.Lancisi-G.Salesi", Ancona, Italy, ³Clinica Medica, Università Politecnica delle Marche, Ancona, Italy
Background/Purpose: Enteropathic spondyloarthritis (ES) are included in the group of the spondyloarthritis (SpA). Because articular involvement is the most frequent extra-intestinal manifestation in patients with…
Abstract Number: 683 • 2015 ACR/ARHP Annual Meeting
Referral Strategies for the Early Diagnosis of Axial Spondyloarthritis- a Systematic Review
Abhijeet Danve¹ and Atul A. Deodhar², ¹Internal Medicine - Rheumatology, University of Nebraska Medical Center, Omaha, NE, ²Division of Arthritis & Rheumatic Diseases, Oregon Health & Science University, Portland, OR
Background/Purpose: Axial Spondyloarthritis (axSpA) is often misdiagnosed or diagnosed late (average delay 8 to 11 years) since low back pain (LBP) is very common in…
Abstract Number: 914 • 2015 ACR/ARHP Annual Meeting
When Fibromyalgia Criteria Misclassify
Frederick Wolfe¹ and Winfried Häuser², ¹National Data Bank, Wichita, KS, ²Department of Psychosomatic Medicine and Psychotherapy, Technische Universität München, Munich, Germany
Background/Purpose : The 2010 American College of Rheumatology (ACR) preliminary criteria for the diagnosis of fibromyalgia (FM2010) and its extension for clinical research by patient self-report…
Abstract Number: 1241 • 2015 ACR/ARHP Annual Meeting
Identification and Validation of Diagnostic and Activity Urinary Metabolomic Biomarkers in Immune-Mediated Inflammatory Diseases
Arnald Alonso¹, Jesús Tornero², Antonio Fernandez-Nebro³, Juan D. Cañete⁴, Eugeni Domènech⁵, Javier P. Gisbert⁶, Carlos Ferrándiz⁵, Eduardo Fonseca⁷, Valle García⁸, Francisco Blanco⁷, Jesus Rodriguez⁹, Jordi Gratacós¹⁰, Patricia E. Carreira¹¹, Antonio Julià¹, Raül Tortosa¹, Maria López-Lasanta¹², Xavier Correig¹³ and Sara Marsal¹, ¹Rheumatology Research Group, Vall d'Hebron Hospital Research Institute, Barcelona, Spain, ²Rheumatology Department, Hospital Universitario Guadalajara, Guadalajara, Spain, ³Rheumatology, Hospital Universitario Carlos Haya, Malaga, Spain, ⁴Unitat d’Artritis, Servei de Reumatologia, Hospital Clínic de Barcelona and Institut d’Investigacions Biomèdiques August Pí i Sunyer, Barcelona, Spain, ⁵Hospital Universitari Germans Trias I Pujol, Badalona, Spain, ⁶Hospital Universitario de la Princesa, Madrid, Spain, ⁷Complejo Hospitalario Juan Canalejo, A Coruña, Spain, ⁸Hospital Universitario Reina Sofía, Córdoba, Spain, ⁹Rheumatology, Hospital Universitari de Bellvitge, Barcelona, Spain, ¹⁰Hospital Parc Taulí, Sabadell, Spain, ¹¹Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain, ¹²Vall d'Hebron Hospital Research Institute, Barcelona, Spain, ¹³CIBERDEM, Metabolomics Platform, Reus, Spain
Background/Purpose: The recent advances in metabolomics have allowed the study of the regulatory processes linked to metabolism. The comprehensive analysis of the metabolome in biological samples…

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