Abstracts tagged "Diagnosis and rheumatoid arthritis (RA)"

Abstract Number: 1482 • 2018 ACR/ARHP Annual Meeting
Is 14.3.3η a Predictor of Development of Rheumatoid Arthritis in Patients with Early Undifferentiated Arthritis?
Karen Marie Carlsen¹, Nina Schmidt², Anne Duer³, Kim Hørslev-Petersen⁴, Cecilie Heegaard Brahe⁵, Merete Lund Hetland², Norma K Biln⁶, Michelle L Zaharik⁷, Bo Jannik Ejbjerg⁸, Lene Bak⁹, Michael Sejer Hansen¹⁰, Julia Sidenius Johansen¹¹, Hanne Merete Lindegaard¹², Jakob M. Møller¹³ and Mikkel Østergaard¹⁴, ¹Center for Rheumatology and Spine Diseases,, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Hillerød, Denmark, Hillerød, Denmark, ²Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, Glostrup, Denmark, ³Department of Radiology, Rigshospitalet Glostrup, Denmark, Glostrup, Denmark, ⁴King Christian the Xth Hospital for Rheumatic Diseases, Denmark, Graasten, Denmark, ⁵Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ⁶Augurex Life Sciences Corp, Vancouver, BC, Canada, ⁷Augurex Life Sciences Corp, Vancouver, DC, Canada, ⁸Rheumatology, Department of Rheumatology, Køge Hospital, Denmark, Køge, Denmark, ⁹Department of Radiology, Odense University Hospital, Denmark, Odense, Denmark, ¹⁰Reuma-Klinik Roskilde, Denmark, Roskilde, Denmark, ¹¹Dept. of Oncology, Department of Oncology, Copenhagen University Hospital, Herlev and Gentofte, Herlev, Denmark, ¹²Dept. of Rheumatology, Department of Rheumatology, Odense University Hospital, Denmark, Odense, Denmark, ¹³Department of Radiology, Copenhagen University Hospital Herlev, Copenhagen, Denmark, ¹⁴Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, Copenhagen, Denmark
Background/Purpose: Optimal management of rheumatoid arthritis (RA) requires early diagnosis and therefore sensitive methods for early identification of RA to prevent joint damage and disability.…
Abstract Number: 2362 • 2017 ACR/ARHP Annual Meeting
Novel Biomarkers for the Prediction of Subclinical Coronary Artery Atherosclerosis in Patients with Rheumatoid Arthritis
Joan Bathon¹, Jenny Van Eyk², Nick Knowlton³, Ivan Ferraz-Amaro⁴, Jon T. Giles⁵, C. Michael Stein⁶, Mary Chester M. Wasko⁷ and Michael Centola⁸, ¹Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ²Advanced Clinical BioSystems Research Institute , Cedars-Sinai Medical Center, Los Angeles, CA, ³Department of Arthritis and Clinical Rheumatology, Oklahoma Medical Research Foundation, Oklahoma, OK, ⁴Rheumatology, Hospital Universitario de Canarias, La Laguna, Tenerife, Spain, ⁵Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ⁶Medicine, Vanderbilt University Medical Center, Nashville, TN, ⁷Lupus Center, Pittsburgh, PA, ⁸Arthritis and Immunology, Oklahoma Medical Research Foundation, Oklahoma, OK
Background/Purpose: Cardiovascular (CV) disease risk prediction models, that were originally developed for use in the general population, have been found to have suboptimal performance in…
Abstract Number: 2965 • 2017 ACR/ARHP Annual Meeting
Non-Invasive Imaging Methods for Evaluating the Cardiovascular Involvement in Patients with Rheumatoid Arthritis before and after 18 Months of Treatment with Anti-TNF Drugs
Fabiola Atzeni¹, Luigi Gianturco², Laura Boccassini³, Piercarlo Sarzi-Puttini³ and Maurizio Turiel⁴, ¹Rheumatology Unit, ASST Fatebenefratelli - Sacco, L. Sacco University Hospital, Milano, Italy, ²Beato Matteo” Hospital, GSD Foundation, Vigevano, Italy, Vigevano, Italy, ³Rheumatology Unit, ASST Fatebenefratelli - Sacco, L. Sacco University Hospital, Milan, Italy, ⁴IRCCS, Galeazzi Orthopedic Institute, Dept. Biomedical Sciences for Health, University of Milan, Milan, Italy
Background/Purpose: The aim of this study was to evaluate left ventricular myocardial function with two- dimensional speckle tracking echocardiography (STE), in addition to conventional Doppler…
Abstract Number: 500 • 2016 ACR/ARHP Annual Meeting
Can Thiol/Disulphide Is a Novel Marker in Rheumatoid Arthritis?
Sema Haliloglu¹, cemile bicer², Murat Alisik³, Bilge Ekinci⁴, Mehmet Emin Budak⁵, Omur volkan⁶, Hulya Uzkeser⁷ and Ayse Carlioglu⁸, ¹Physical Medicine and Rehabilitation, Maltepe Occupational Diseases Hospital, Istanbul, Turkey, ²Biochemistry, Yildirim Beyazit University Medical Faculty, Ankara, Turkey, ³Biochemistry, Ataturk Training and Research Hospital, Ankara, Turkey, ⁴Physical Medicine and Rehabilitation, Erzurum Region Training and Research Hospital, Erzurum, Turkey, ⁵Endocrinology, Erzurum Region Training and Research Hospital, erzurum, Turkey, ⁶Rheumatology, Erzurum Region Training and Research Hospital, Erzurum, Turkey, ⁷Physical Medicine and Rehabilitation, Ataturk University,Medical Faculty, Erzurum, Turkey, ⁸Endocrinology, Erzurum Region Training and Research Hospital, Erzurum, Turkey
Background/Purpose: Rheumatoid arthritis is a chronic, systemic, autoimmune disease about 5% -%1 of world population affected. Highly reactive oxygen free radicals are believed to be…
Abstract Number: 1037 • 2016 ACR/ARHP Annual Meeting
Evaluation of 14-3-3η As a Tool for Diagnosis of Early RA in a European Cohort
Monika Hansson¹, Linda Mathsson-Alm², Anthony Marotta³ and Sascha Swiniarski⁴, ¹Rheumatology Unit, Department of Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden, ²Thermo Fisher Scientific, Uppsala, Sweden, ³Augurex Life Sciences Corp., Vancouver, BC, Canada, ⁴ImmunoDiagnostics Division Thermo Fisher Scientific, Phadia GmbH, Freiburg, Germany
Background/Purpose: Early diagnosis of rheumatoid arthritis (RA) coupled with an effective treatment strategy is a key imperative in the effective management of disease. Anti-citrullinated peptide…
Abstract Number: 1508 • 2016 ACR/ARHP Annual Meeting
Prevalence and Clinical Characteristics of Rheumatoid Arthritis in Sickle Cell Patients: A Cross-Sectional Analysis
David J. Ozeri¹, Joshy Pathiparampil², Randolph Sanchez² and Isabel M. McFarlane³, ¹Rheumatology, SUNY Downstate Medical Center, brooklyn, NY, ²Internal Medicine, SUNY Downstate Medical Center, Brooklyn, NY, ³Rheumatology, SUNY Downstate Medical Center, Brooklyn, NY
Title: Prevalence and Clinical Characteristics of Rheumatoid Arthritis in Sickle Cell Patients Background/Purpose: Rheumatoid arthritis (RA) has been rarely reported in association with sickle cell…
Abstract Number: 493 • 2015 ACR/ARHP Annual Meeting
Diagnostic Delay in Early Arthritis: Ten Years-Experience of a Single Center
Francesca Benaglio, Silvia Balduzzi, Serena Bugatti, Garifallia Sakellariou, Carlomaurizio Montecucco and Roberto Caporali, Division of Rheumatology, University of Pavia, IRCCS S. Matteo Foundation, Pavia, Italy, Pavia, Italy
Background/Purpose: In the last 10 years a big effort has been made to reduce the diagnostic delay in patients with early arthritis, in order to…
Abstract Number: 1869 • 2013 ACR/ARHP Annual Meeting
Serum Cytokine/Chemokine Profiles Are Useful For Evaluating Pathological Conditions Of Rheumatoid Arthritis and Diagnosing Anti-CCP Antibody-Negative Patients
Hitoshi Uga¹, Takahiro Okazawa¹, Yoshiaki Miyamoto¹, Takehiro Hasegawa¹, Jun Saegusa², Goh Tsuji³, Sho Sendo⁴, Akio Morinobu⁵, Shunichi Kumagai^6,7 and Hirokazu Kurata¹, ¹Sysmex Corporation, Kobe, Japan, ²Department of Evidence-based Laboratory Medicine, Kobe University Graduate School of Medicine, Kobe, Japan, ³Center for Rheumatic Diseases, Shinko Hospital, Kobe, Japan, ⁴Center of rheumatic diseases, Shinko Hospital, Kobe, Japan, ⁵Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan, ⁶Center of rheumatic diseases, Shinko hospital, Kobe, Japan, ⁷Department of Evidence-Based Laboratory Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
Background/Purpose: The diagnosis of anti-CCP antibody (ACPA) negative rheumatoid arthritis (RA) are known to be difficult and delayed as compared with ACPA-positive RA. This study…
Abstract Number: 1786 • 2013 ACR/ARHP Annual Meeting
91% Of Early RA Patients Are Positive For Serum 14-3-3η Or Its Auto-Antibodies
Walter P. Maksymowych¹, Dirkjan van Schaardenburg², Désirée van der Heijde³, Robert Landewé⁴, Gilles Boire⁵, Maarten Boers⁶, Vivian P. Bykerk⁷, Edward C. Keystone⁸, Katherine A. Siminovitch⁹, Mairead Murphy¹⁰ and Anthony Marotta¹¹, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Jan van Breemen Research Institute | Reade, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Int Med/Rheumatology, Academic Medical Center, Amsterdam, Netherlands, ⁵Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁶Epidemiology & Biostatistics, VU University Medical Center, Amsterdam, Netherlands, ⁷Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, ⁸Department of Medicine, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁹Mount Sinai Hospital, Toronto, ON, Canada, ¹⁰Augurex Life Sciences Corp., North Vancouver, BC, Canada, ¹¹Augurex Life Sciences Corp, North Vancouver, BC, Canada
Background/Purpose: Current serological markers such as RF and ACPA are useful for early diagnosis and perhaps for screening people at risk, but there remains a…
Abstract Number: 876 • 2013 ACR/ARHP Annual Meeting
Prediction Of TNF Inhibitor Response In Rheumatoid Arthritis Patients Using Single Cell Network Profiling Of Intracellular Immune Signaling
Jason Ptacek¹, Rachael Hawtin², Brent Louie¹, Erik Evensen¹, James Cordeiro¹, Barbara Mittleman¹, Michelle Atallah¹, Alessandra Cesano², Clifton O. Bingham III³, Stacey Cofield⁴, Jeffrey R. Curtis⁵, Maria I. Danila⁴, Richard A. Furie⁶, MC Genovese⁷, Marc C. Levesque⁸, Larry W. Moreland⁸, Peter A. Nigrovic⁹, James R. O'Dell¹⁰, William H. Robinson¹¹, Nancy A. Shadick⁹, E. William St Clair¹², Christopher C. Striebich¹³, Geoffrey M Thiele¹⁴, Peter K. Gregersen⁶ and S. Louis Bridges Jr.⁴, ¹Nodality, Inc., South San Francisco, CA, ²Nodality Inc., South San Francisco, CA, ³Rheumatology, Johns Hopkins University, Baltimore, MD, ⁴University of Alabama at Birmingham, Birmingham, AL, ⁵Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁶The Feinstein Institute for Medical Research and North Shore-Long Island Jewish Health System, Lake Success, NY, ⁷Stanford University, Palo Alto, CA, ⁸University of Pittsburgh, Pittsburgh, PA, ⁹Brigham and Women's Hospital/Harvard University, Cambridge, MA, ¹⁰Veteran Affairs Nebraska Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, ¹¹VA Palo Alto Health Care System and Stanford University, Palo Alto, CA, ¹²Medicine, Duke Unversity Medical Center, Durham, NC, ¹³University of Colorado Denver, Aurora, CO, ¹⁴Omaha VA and the University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Biomarkers predictive of drug efficacy are lacking in rheumatoid arthritis (RA) and would be useful in clinical practice and clinical trials. Single cell…
Abstract Number: 2264 • 2013 ACR/ARHP Annual Meeting
An Assay Panel Combining Anticitrullinated Peptide Autoantibodies and Rheumatoid Factor Isotypes Has High Yield In The Diagnosis Of Rheumatoid Arthritis
Nirupa J. Patel¹, Ignacio Garcia-Valladares², Derren Barken³, Luis R. Espinoza⁴, Heena Sheth⁵ and Thierry Dervieux⁶, ¹Rheumatology, LSU Health Sciences Ctr, New Orleans, LA, ²Rheumatology, Guadalajara, Guadalajara, Mexico, ³Exagen Diagnostics, Vista, CA, ⁴Medicine-Section of Rheum, LSU Medical Center, New Orleans, LA, ⁵Medicine, University of Pittsburgh, Pittsburgh, PA, ⁶Research and Development, Exagen Diagnostics, Vista, CA
Background/Purpose: We sought to establish the diagnostic performances of rheumatoid factor isotypes (IgM and IgA) and anti-citrullinated peptide antibodies (ACPAs: anti-mutated citrullinated vimentin [anti-MCV] and…
Abstract Number: 2132 • 2012 ACR/ARHP Annual Meeting
Disease Activity and Anti-CCP Status, but Not Sociodemographic Factors or Patient Comorbidities, Affect Time to Diagnosis in Early Rheumatoid Arthritis
Cheryl Barnabe¹, Juan Xiong², Gilles Boire³, Carol A. Hitchon⁴, Boulos Haraoui⁵, Janet E. Pope⁶, J. Carter Thorne⁷, Edward Keystone⁸, Diane Tin⁹, Vivian P. Bykerk¹⁰ and Canadian ArThritis CoHort¹¹, ¹Medicine, Community Health Sciences, University of Calgary, Calgary, AB, Canada, ²University of Toronto, Toronto, Canada, ³Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁴University of Manitoba, Winnipeg, MB, Canada, ⁵Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ⁶Medicine/Rheumatology, St. Joseph Health Care London, University of Western Ontario, London, ON, Canada, ⁷Southlake Regional Health Centre, Newmarket, ON, Canada, ⁸University of Toronto, Toronto, ON, Canada, ⁹The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹⁰Rheumatology, Hospital for Special Surgery, New York, NY, ¹¹Toronto
Background/Purpose: Delays in patient presentation to primary care providers, subsequent referral for rheumatology assessment, and recognition of rheumatoid arthritis (RA) by the rheumatologist increase time…
Abstract Number: 2096 • 2012 ACR/ARHP Annual Meeting
A Prediction Rule for the Progression to Rheumatoid Arthritis Applied in a Mexican Mestizo Cohort with Undifferentiated Arthritis
Ana Arana Guajardo, Lorena Pérez Barbosa, David Vega Morales, Janett Riega Torres, Roberto Negrete López, Jacqueline Rodríguez Amado, Jorge Esquivel Valerio, Cassandra Skinner Taylor, Diana Flores Alvarado, Dionicio Galarza Delgado, Miguel Villarreal Alarcon and Mario Garza Elizondo, Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico
Background/Purpose: A high proportion of patients who present with recent-onset arthritis have undifferentiated arthritis (UA), as these patients do not fulfill the classification criteria for…
Abstract Number: 441 • 2012 ACR/ARHP Annual Meeting
Performance of Anti-Cyclic Citrullinated Peptide Assays Differs in Healthy Subjects At Elevated Risk for Future Rheumatoid Arthritis and Subjects with Established Disease
M. Kristen Demoruelle¹, Mark Parish², Lezlie A. Derber³, Michael H. Weisman⁴, William R. Gilliland⁵, Jess Edison⁶, James R. O'Dell⁷, Ted R. Mikuls⁸, Richard M. Keating⁹, Peter K. Gregersen¹⁰, Jane H. Buckner¹¹, Jill M. Norris¹², V. Michael Holers¹³ and Kevin D. Deane¹, ¹Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ²Rheumatology, University of Colorado Anschutz Medical Campus, Aurora, CO, ³University of Colorado School of Medicine, Division of Rheumatology, Aurora, CO, ⁴Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Walter Reed National Military Medical Center, Bethesda, MD, ⁶Department of Rheumatology, Walter Reed National Military Medical Center, Bethesda, MD, ⁷Dept of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ⁸Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ⁹Rheumatology Section, The University of Chicago, Chicago, IL, ¹⁰Genomics and Human Genetics, North Shore University Hospital Research Center, Manhasset, NY, ¹¹Benaroya Research Institute at Virginia Mason, Seattle, WA, ¹²Epidemiology, Colorado School of Public Health, Aurora, CO, ¹³Rheumatology Division, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: The 2010 ACR/EULAR RA criteria include autoantibodies to cyclic citrullinated peptides (CCP) that are highly specific for RA in the setting of inflammatory arthritis…

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