Abstracts tagged "depression"

Abstract Number: 1414 • 2019 ACR/ARP Annual Meeting
Improvement of Mental Health and Quality of Life During Therapy with Tocilizumab
Frank Behrens¹, Werner A Biewer ², Gerd Burmester ³, Martin Feuchtenberger ⁴, Michael W. Hofmann ⁵, Peter Kästner ⁶, Herbert Kellner ⁷, Ramona König ⁸, Anke Liebhaber ⁹, Christina Luig ¹⁰, Regina Max ¹¹, Patrizia Sternad ¹², Hans-Peter Tony ¹³ and Christopher Amberger ¹⁴, ¹Rheumatology Goethe-University Frankfurt & Fraunhofer IME-TMP, Frankfurt, Germany, ²Rheumatologische Schwerpunktpraxis Saarbrücken, Saarbrücken, Germany, ³Charité—University Medicine Berlin, Berlin, Germany, ⁴Rheumatologie/Klinische Immunologie, Kreiskliniken Altötting-Burghausen, Burghausen, Germany, ⁵Chugai Pharma Europe Ltd., Frankfurt/Main, Germany, ⁶MVZ Ambulantes Rheumazentrum Erfurt, Erfurt, Germany, ⁷Praxis Prof. Herbert Kellner, Munich, Germany, ⁸Justus-Liebig-Universität Giessen and Kerckhoff-Klinik-Forschungs-GmbH, Giessen, Germany, ⁹Internistisch-Rheumatologische Arztpraxis, Halle, Halle, Germany, ¹⁰Roche Pharma AG, Rheumatologie, Grenzach-Wyhlen, Germany, ¹¹Universitätsklinikum Heidelberg, Heidelberg, Germany, ¹²Gemeinschaftspraxis, Planegg, Planegg, Germany, ¹³Department of Rheumatology/Clinical Immunology, University Hospital, Wuerzburg, Germany, Würzburg, Germany, ¹⁴Rheumatologische Gemeinschaftspraxis Dr. Pick/Dr. Amberger, Bad Neuenahr, Germany
Background/Purpose: In rheumatoid arthritis (RA), the proinflammatory cytokine IL-6 is associated with mental disorders such as depression and anxiety.1 Furthermore, depression and anxiety are comorbidities…
Abstract Number: 1444 • 2019 ACR/ARP Annual Meeting
Tofacitinib in Patients with Rheumatoid Arthritis and Indicative of Depression And/or Anxiety: A Post Hoc Analysis of Phase 3 and Phase 3b/4 Clinical Trials
Gustavo Citera¹, Rakesh Jain ², Fedra Irazoque ³, Renato Guzman ⁴, Hugo Madariaga ⁵, David Gruben ⁶, Lisy Wang ⁶, Lori Stockert ⁷, Ming-Ann Hsu ⁸, Karina Santana ⁹, Abbas Ebrahim ¹⁰ and Dario Ponce de Leon ¹¹, ¹Instituto de Rehabilitación Psicofísica, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, ²Texas Tech University School of Medicine, Lubbock, TX, ³Hospital Angeles Mocel, San Miguel, Mexico, ⁴Fundación Universitaria Juan N. Corpas e IDEARG, Bogota, Colombia, ⁵Clínica del Sur, Arequipa, Peru, ⁶Pfizer Inc, Groton, CT, ⁷Pfizer Inc, Collegeville, PA, ⁸Pfizer Inc, Groton, ⁹Pfizer Inc, Mexico City, Mexico, ¹⁰Pfizer Inc, Collegeville, ¹¹Pfizer Inc, Lima, Peru
Background/Purpose: Depression and anxiety are common in patients (pts) with RA1 and can lead to reduced quality of life, functional capacity, and RA treatment response.2-4…
Abstract Number: 1490 • 2019 ACR/ARP Annual Meeting
Blockage of TNFα and IL-12/23 Improves Depressive Symptoms in Patients with Psoriatic Arthritis – Analysis of Clinical Trial Data
Lihi Eder¹, Alexis Ogdie ² and Yujie Zhong ³, ¹Women’s College Hospital and the Department of Medicine, University of Toronto, Toronto, Canada, ²Department of Medicine and Rheumatology and Department of Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, ³School of Statistics and Management, Shanghai University of Finance and Economics, Cambridge, China (People's Republic)
Background/Purpose: The prevalence of depression is increased in patients with psoriatic arthritis (PsA). Little is known about the impact of effective control of inflammation on…
Abstract Number: 2822 • 2019 ACR/ARP Annual Meeting
Depression and Subsequent Risk for Incident Seronegative Rheumatoid Arthritis Among Women
Jeffrey Sparks¹, Susan Malspeis ¹, Jill Hahn ², Andrea Roberts ², Laura Kubzansky ² and Karen Costenbader ¹, ¹Brigham and Women's Hospital, Boston, MA, ²Harvard School of Public Health, Boston, MA
Background/Purpose: Depression is associated with elevated systemic inflammation and risk of several chronic diseases including lupus, psoriasis, and inflammatory bowel disease. However, the association between…
Abstract Number: 1741 • 2019 ACR/ARP Annual Meeting
Depression and Anxiety Symptoms in Childhood-Onset Systemic Lupus Erythematosus
Kate Neufeld¹, Frank Silverio ², Lawrence Ng ³, Ashley Danguecan ⁴, Daniela Dominguez ³, Reva Schachter ², Michelle Quilter ⁵, Julie Couture ⁶, Daphne Korczak ⁷, Deborah Levy ⁸, Linda Hiraki ⁹, Earl D. Silverman ¹⁰ and Andrea Knight ¹¹, ¹Division of Rheumatology, The Hospital For Sick Children, University of Toronto, Toronto, Canada, ²The Hospital for Sick Children, Toronto, Canada, ³Division of Rheumatology, The Hospital for Sick Children, Toronto, Canada, ⁴Division of Rheumatology and Dept of Psychology, The Hospital For Sick Children, Toronto, Canada, ⁵Department of Psychiatry,The Hospital For Sick Children, Toronto, Canada, ⁶The Hospital for Sick Children, Montreal, Canada, ⁷Dept of Psychiatry, SickKids and Dept of Psychiatry, University of Toronto, Toronto, Canada, ⁸Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁹Division of Rheumatology, The Hospital for Sick Children, Department of Paediatrics, University of Toronto, Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Canada, ¹⁰Division of Rheumatology, The Hospital for Sick Children, Department of Paediatrics, University of Toronto, Translational Medicine, Research Institute, The Hospital for Sick Children, Toronto, Canada, ¹¹Division of Rheumatology, The Hospital for Sick Children, Department of Paediatrics, University of Toronto, Toronto, ON, Canada
Background/Purpose: Depression and anxiety disorders are common in patients with childhood-onset systemic lupus erythematosus (cSLE). It is unclear if they are due to central nervous…
Abstract Number: 1844 • 2019 ACR/ARP Annual Meeting
The Contribution of Disease Activity, Depression, and Anxiety to Health-Related and Non-Health-Related Quality of Life in US and Filipino Patients with SLE
Alexandra Watts¹, Desiree Azizoddin ², Shadi Gholizadeh ³, Sarah Mills ⁴, Geraldine Zamora ⁵, Daniel Wallace ⁶, Meenakshi Jolly ⁷, Michael Weisman ⁸ and Perry Nicassio ⁹, ¹University of California, Los Angeles, Los Angeles, CA, ²Dana-Farber Cancer Institute, Boston, MA, ³McGill University, Montreal, Canada, ⁴Lineberger Comprehensive Cancer Center, Chapel Hill, NC, ⁵Manila Doctors Hospital, Manila, Philippines, ⁶Cedars-Sinai Medical Center/University California at Los Angeles, Los Angeles, CA, ⁷Rush University Medical Center, Chicago, IL, ⁸David Geffen School of Medicine at UCLA, Los Angeles, CA, ⁹David Geffen School of Medicine, Los Angeles, CA
Background/Purpose: It is well known that patients with SLE are often afflicted with deficits in quality of life and problems with physical impairment and psychosocial…
Abstract Number: 2398 • 2019 ACR/ARP Annual Meeting
Prevalence of Anxiety and Depression in a Cohort of Patients with Rheumatic Diseases on Biological Infusions
Alexander Peck¹, Ella Starobinska ², Gilbert Ortega ¹, Jaclyn Leong ¹, Travis Maestas ¹, Phan Saligrama ¹, Jawad Bilal ¹ and Dominick Sudano ³, ¹University of Arizona College of Medicine, Tucson, AZ, ²University of Arizona College of Medicine, Tucson, AL, ³Banner University Medical Center Tucson, Tucson
Background/Purpose: Studies have shown an increased prevalence of psychologic disorders in rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, and psoriatic arthritis, compared to…
Abstract Number: 2450 • 2019 ACR/ARP Annual Meeting
The Paradoxical Effect of Depression on Psoriatic Arthritis Outcomes in a Combined Psoriasis-Psoriatic Arthritis Center
Rebecca Haberman¹, Samrachana Adhikari ¹, Deborah Ramirez ², Eileen Lydon ¹, Malavika Attur ¹, Andrea Neimann ¹, Soumya Reddy ¹, Andrea Troxel ¹ and Jose Scher ³, ¹NYU School of Medicine, New York City, ²NYU School of Medicine, New York, ³New York University School of Medicine, New York, NY
Background/Purpose: Psoriatic arthritis (PsA) is a heterogenous inflammatory disease affecting skin, joints, and other domains. While psychiatric diseases (i.e., depression and anxiety) are known comorbidities,…
Abstract Number: 339 • 2019 ACR/ARP Annual Meeting
Depressive Symptoms Influence Success of Allopurinol in Reducing Serum Urate
Sylvie Mrug ¹, Catheryn Orihuela ¹, Elizabeth Rahn ², Amy Mudano ¹, Kenneth Saag ², Jeffrey Foster ² and Angelo Gaffo², ¹University of Alabama at Birmingham, Birmingham, ²University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Elevated levels of serum urate (sUA) are central to the pathogenesis of gout and have been associated with cardiovascular disease. Urate-lowering therapies are effective…
Abstract Number: 261 • 2018 ACR/ARHP Annual Meeting
Mindfulness Is Associated with Sleep Quality Among Patients with Fibromyalgia
Michelle Park¹, Yuan Zhang², Lori Lyn Price^3,4, Raveendhara R. Bannuru¹ and Chenchen Wang¹, ¹Division of Rheumatology, Center for Complementary and Integrative Medicine, Tufts Medical Center, Boston, MA, ²Susan and Alan Solomont School of Nursing, University of Massachusetts Lowell, Lowell, MA, ³Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁴Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA
Background/Purpose: Poor and disturbed sleep is an important disabling feature of fibromyalgia. Previous studies suggest higher mindfulness may be associated with better sleep quality in…
Abstract Number: 348 • 2018 ACR/ARHP Annual Meeting
Psychometric Validation of the Arthritis Helplessness Index in Systemic Lupus Erythematosus
Shadi Gholizadeh¹, Desiree R Azizoddin², Sarah D. Mills³, Geraldine Zamora Racaza⁴, Hi'Ilani Mary Kala'aukahi Potemra⁵, Daniel J. Wallace⁶, Michael Weisman⁷ and Perry M. Nicassio⁸, ¹SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, ²Department of Anesthesiology, Stanford University School of Medicine, Palo Alto, CA, ³Medicine, Lineberger Comprehensive Cancer Center University of North Carolina, Durham, NC, ⁴Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁵University of California, Los Angeles, Los Angeles, CA, ⁶Geffen School of Medicine at UCLA, West Hollywood, CA, ⁷Harbor UCLA Medical Center, Los Angeles, CA, ⁸Cousins Center for PNI, UCLA, LA, CA
Background/Purpose: Helplessness is a relevant construct in systemic lupus erythematosus (SLE), an unpredictable chronic illness with no known cure characterized by relapsing and remitting features.…
Abstract Number: 489 • 2018 ACR/ARHP Annual Meeting
Self-Reported Depression in Patients with Rheumatoid Arthritis Is Undertreated and Associated with Poorer Clinical Status and Lower Rates of Remission in Routine Care
Isabel Castrejón, Mariam Riad, Jacquelin R. Chua and Theodore Pincus, Division of Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Depression in patients with rheumatoid arthritis (RA) may be pre-existent, amplified, or newly-developed after onset of RA. Together with other comorbidities, socioeconomic factors, education…
Abstract Number: 747 • 2018 ACR/ARHP Annual Meeting
The Influence of Depression on Clinical Features of Systemic Lupus Erythematosus
Amanda M. Eudy¹, Jennifer Rogers², Lisa Criscione-Schreiber¹, David Pisetsky³, Kai Sun⁴, Jay Doss⁴ and Megan E. B. Clowse¹, ¹Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC, ²Medicine, Divison of Rheumatology, Duke University, Durham, NC, ³Department of Medicine, Duke University, Durham, NC, ⁴Division of Rheumatology & Immunology, Duke University, Durham, NC
Background/Purpose: Depression occurs commonly among patients with SLE. In this study, we used two separate scales to assess depression and determined differences in clinical characteristics…
Abstract Number: 1163 • 2018 ACR/ARHP Annual Meeting
Patterns of Depressive Symptoms before and after Surgery for Hip, Knee and Lumbar Spine Osteoarthritis
J. Denise Power, Prtha Kudesia, Alina Nadeem, Anthony V. Perruccio, Y. Raja Rampersaud, Nizar Mahomed and Rajiv Gandhi, Arthritis Program, Krembil Research Institute, University Health Network, Toronto, ON, Canada
Background/Purpose: Although pain and decreased function are the primary symptom targets of OA surgeries, OA is also associated with depression. The impact of surgery on…
Abstract Number: 1165 • 2018 ACR/ARHP Annual Meeting
Restless Sleep Trajectories over 8 Years: Data from the Osteoarthritis Initiative
Jing Song¹, Julia (Jungwha) Lee¹, Yvonne C. Lee², Alison H. Chang¹, Pamela Semanik³, Linda S. Ehrlich-Jones¹, Rowland W. Chang¹ and Dorothy D. Dunlop¹, ¹Northwestern University, Chicago, IL, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³College of Nursing, Rush University, Chicago, IL
Background/Purpose: Sleep disturbance has been recognized as a major public health issue. Evidence has shown that individuals with osteoarthritis (OA) are more likely to have…

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