Abstracts tagged "dendritic cells and metabolism"

Abstract Number: 481 • 2016 ACR/ARHP Annual Meeting
Dual Effect of 3-Bromopyruvate on Both Th17 and Treg Cell Differentiation and Dendritic Cell Activation Ameliorates Autoimmune Arthritis in Mice
Takaichi Okano¹, Jun Saegusa², Keisuke Nishimura³, Yo Ueda⁴, Sho Sendo², Soshi Takahashi⁵, Kengo Akashi³, Akira Onishi⁶ and Akio Morinobu², ¹Rheumatology and Clinical immunology, Kobe University Graduate School of Medicine, Kobe, Japan, ²Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan, ³Department of Rheumatology, Kobe University Hospital, Kobe, Japan, ⁴Kobe University Graduate School of Medicine, Kobe, Japan, ⁵Department of Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan, ⁶Department for Rheumatology, Kobe University Hospital, Kobe, Japan
Background/Purpose: Recent studies have shown that cellular metabolism plays an important role in regulating immune cell function. In the process of cell differentiation, both interleukin-17-producing…