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Abstracts tagged "dendritic cells and metabolism"

  • Abstract Number: 481 • ACR/ARHP Annual Meeting 2016

    Dual Effect of 3-Bromopyruvate on Both Th17 and Treg Cell Differentiation and Dendritic Cell Activation Ameliorates Autoimmune Arthritis in Mice

    Takaichi Okano1, Jun Saegusa2, Keisuke Nishimura3, Yo Ueda4, Sho Sendo2, Soshi Takahashi5, Kengo Akashi3, Akira Onishi6 and Akio Morinobu2, 1Rheumatology and Clinical immunology, Kobe University Graduate School of Medicine, Kobe, Japan, 2Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan, 3Department of Rheumatology, Kobe University Hospital, Kobe, Japan, 4Kobe University Graduate School of Medicine, Kobe, Japan, 5Department of Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan, 6Department for Rheumatology, Kobe University Hospital, Kobe, Japan

    Background/Purpose: Recent studies have shown that cellular metabolism plays an important role in regulating immune cell function. In the process of cell differentiation, both interleukin-17-producing…

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