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Abstracts tagged "dendritic cells and interleukins (IL)"

  • Abstract Number: 2927 • ACR/ARHP Annual Meeting 2016

    Mechanisms Regulating the Loss of Tregs in CD11c-Flip-KO Mice That Contribute to the Spontaneous Development of Inflammatory Arthritis

    Qi Quan Huang1, Renee E. Doyle2, Robert Birkett1, Deyu Fang3 and Richard M. Pope2, 1Medicine/Rheumatology, Northwestern University Feinberg school of Medicine, Chicago, IL, 2Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose: CD11c-Flip-KO (HUPO) mice spontaneously develop inflammatory, erosive arthritis. We previously demonstrated that T regulatory cells (Tregs) were reduced in HUPO mice and that the…
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