Abstracts tagged "dendritic cells and hormones"

Abstract Number: 2790 • 2016 ACR/ARHP Annual Meeting
Selective Disruption of Estrogen Receptor Alpha Expression in Dendritic Cells of Lupus-Prone Mice Results in Increased Female-Specific Death
Melissa A. Cunningham¹, Jena R. Wirth², Jackie G. Eudaly² and Gary S. Gilkeson³, ¹Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC, ²Med/Rheumatology, Medical University of South Carolina, Charleston, SC, ³Department of Medicine, Medical University of South Carolina, Charleston, SC
Background/Purpose: SLE is a disease that disproportionately affects females. The etiology of the sex bias in this disease is unclear. We previously showed that a…
Abstract Number: 1213 • 2014 ACR/ARHP Annual Meeting
Absence of Hormone Responsive Estrogen Receptor Alpha Reduces the Activation of Plasmacytoid Dendritic Cells in Lupus Prone Mice
Jennifer L. Scott¹, Melissa A. Cunningham², Osama S. Naga³, Jackie G. Eudaly³, Jena R. Wirth⁴ and Gary S. Gilkeson⁵, ¹Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, ²Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC, ³Medicine/Rheumatology, Medical University of South Carolina, Charleston, SC, ⁴Med/Rheumatology, MUSC, Charleston, SC, ⁵Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC
Background/Purpose Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that affects women at a 9 to 1 ratio compared to men. To further understand…
Abstract Number: 637 • 2014 ACR/ARHP Annual Meeting
Decreased Inflammatory Dendritic Cells in Lupus-Prone Estrogen Receptor Alpha Knockout (ERαKO) Mice Correlate with Increased Survival
Melissa A. Cunningham¹, Jena R. Wirth², Jackie G. Eudaly³, Jennifer L. Scott⁴, Osama S. Naga³ and Gary S. Gilkeson⁵, ¹Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC, ²Med/Rheumatology, MUSC, Charleston, SC, ³Medicine/Rheumatology, Medical University of South Carolina, Charleston, SC, ⁴Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, ⁵Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC
Background/Purpose: SLE is a disease that disproportionately affects females. The etiology of the sex bias in this disease is unclear. We previously showed that a…

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