Abstracts tagged "dendritic cells and growth factors"

Abstract Number: 2090 • 2012 ACR/ARHP Annual Meeting
Orchestrating the Orchestrators: Blockade of Flt3L Signaling-Dependent Dendritic Cells Protects Against Collagen Induced Arthritis
Maria I. Martins Ramos¹, Karpus O.N. Karpus², Pleun Broekstra², Saïda Aarrass³, Paul P. Tak⁴ and Maria C. Lebre³, ¹Division of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ²Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ³Clinical Immunology and Rheumatology & Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ⁴Department of Experimental Immunology, Division of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam and GlaxoSmithKline, Amsterdam, Netherlands
Background/Purpose: Autoimmune diseases often result from inappropriate or unregulated activation of autoreactive T cells. The induction and maintenance of T cell tolerance to tissue antigens…

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