ACR Meeting Abstracts

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Abstracts tagged "dendritic cells and Autoimmune Skin Disease"

  • Abstract Number: 1296 • 2019 ACR/ARP Annual Meeting

    Increased MxA Protein Expression and Dendritic Cells in Spongiotic Dermatitis Differentiates Dermatomyositis from Eczema

    Majid Zeidi1, Kristen Chen 1, Basil Patel 2, Rachel Lim 3 and Victoria Werth 1, 1Corporal Michael J. Crescenz VAMC, Philadelphia, PA, USA and Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA, Philadelphia, PA, 2Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA, Philadelphia, PA, 3Corporal Michael J. Crescenz VAMC, Philadelphia, PA, USA, Philadelphia

    Background/Purpose: Dermatomyositis (DM) is conventionally characterized by interface dermatitis (ID) on skin histopathology. A subset of patients with clinically diagnosed DM have skin biopsies showing…
  • Abstract Number: 1869 • 2019 ACR/ARP Annual Meeting

    Myeloid Dendritic Cells (mDCs) Are Major Producers of Interferon-β in Dermatomyositis and Higher Numbers of mDCs Are Found in Hydroxychloroquine Nonresponders

    Kristen Chen1, Majid Zeidi 1, Maria Wysocka 2, Nithin Reddy 1, Arvin Jadoo 1, Muhammad Bashir 1, Sarah Ahmed 2, Basil Patel 2, Kevin Zhang 2, Barbara White 3 and Victoria Werth 1, 1Corporal Michael J. Crescenz VAMC, Philadelphia, PA, USA and Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA, Philadelphia, PA, 2Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA, Philadelphia, PA, 3Corbus Pharmaceuticals, Norwood, MA

    Background/Purpose: Dermatomyositis (DM) is an autoimmune disease affecting the skin, skeletal muscle, lungs, and/or other organs. While the pathogenesis remains poorly understood, it is thought…
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ACR Pediatric Rheumatology Symposium 2020

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