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Abstracts tagged "Defibrotide and catastrophic antiphospholipid syndrome"

  • Abstract Number: 1789 • 2019 ACR/ARP Annual Meeting

    Defibrotide Inhibits Antiphospholipid Antibody-Mediated NET Release and Endothelial Cell Activation

    Ramadan Ali1, Hui Shi 1, Srilakshmi Yalavarthi 1 and Jason Knight 2, 1University of Michigan, Ann Arbor, MI, 2Division of Rheumatology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI

    Background/Purpose: Defibrotide is a mixture of phosphodiester oligonucleotides derived from porcine intestinal mucosa, currently approved for treatment of hepatic sinusoidal obstruction syndrome. Defibrotide has been…
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