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Abstracts tagged "Cytotoxic and Gene Expression"

  • Abstract Number: 2 • ACR/ARP Annual Meeting 2019

    Baseline Cytotoxic Gene Expression Associates with Ustekinumab Response in Systemic Lupus Erythematosus

    Loqmane Seridi1, Matteo Cesaroni 1, Matthew Loza 1, Jessica Schreiter 1, Kristen Sweet 1, Yevgeniya Orlovsky 1, Isabelle Baribaud 1, Ashley Orillion 1, Peter Lipsky 2, Ronald van Vollenhoven 3, Bevra Hahn 4, George Tsokos 5, Marc Chevrier 1, Shawn Rose 1, Frédéric Baribaud 1 and Jarrat Jordan 1, 1Janssen Research & Development, LLC, Spring House, PA, 2AMPEL BioSolutions, LLC, Charlottesville, VA, 3Amsterdam Rheumatology and Immunology Center, Amsterdam, Netherlands, 4University of California, Los Angeles, CA, 5Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

    Background/Purpose: Systemic Lupus Erythematous (SLE) is a clinically and biologically diverse disease, for which only one new therapy has been approved in the past 60…

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