Abstracts tagged "cytokines and synovitis"

Abstract Number: 896 • 2012 ACR/ARHP Annual Meeting
Tyro3, Axl, MerTK-Receptor Activation by Gas6 or Pros1 Gene Delivery, ameliorates Collagen-induced arthritis
Fons A.J. van de Loo¹, Ben T. van Den Brand², Shahla Abdollahi-Roodsaz³, Eline A. Vermeij⁴, Miranda B. Bennink⁴, Onno J. Arntz⁵ and Wim B. van den Berg⁶, ¹Rheumatology Research & Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ³Rheumatology Research and Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ⁴Rheumatology Research and Advanced Therapeutics, Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ⁵Rheumatology Research and Advanced Therapeutics, Department of Rheumatology, Nijmegen, Netherlands, ⁶Experimental Rheumatology (272), Radboud university medical center, Nijmegen, Netherlands
Background/Purpose: Insufficient controlled activation of innate immunity by cytokines and pattern recognition receptors could develop into auto-immune diseases. Stimulation of dendritic cells via the Axl receptor…