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Abstracts tagged "Cytokines and osteoclasts"

  • Abstract Number: 27 • ACR/ARHP Annual Meeting 2014

    CD115+ Osteoclast Precursors Arise before Clinical Onset of Arthritis and Are Regulated By Proinflammatory Cytokines

    Antonia Puchner1, Victoria Saferding2, Eliana Goncalves-Alves3, Silvia Hayer4, Harald Leiss1, Josef Smolen5, Kurt Redlich6 and Stephan Blüml1, 1Department of Rheumatology, Medical University of Vienna, Vienna, Austria, 2Rheumatology, Medical University of Vienna, Vienna, Austria, 3rheumatology, Medical University of Vienna, Vienna, Austria, 4Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 5Department of Rheumatology, Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 6Division of Rheumatology, Medical University of Vienna, Vienna, Austria

    Background/Purpose Bone erosions and systemic bone loss in rheumatoid arthritis patients results from an increased activity of osteoclasts, which are derived from precursor cells of…

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