ACR Meeting Abstracts

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Abstracts tagged "cytokines and myositis"

  • Abstract Number: 1032 • 2018 ACR/ARHP Annual Meeting

    Aberrant Sarcoplasmic Expression of the Alarmin ‘High Mobility Group Box Protein 1” (HMGB1) in Patients with Idiopathic Inflammatory Myopathy

    Jessica Day1, Sophia Otto2, Kathy Cash3, Preethi Eldi4, Pravin Hissaria5, Susanna Proudman6, John Hayball4 and Vidya Limaye7, 1Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia, 2Pathology, Royal Adelaide Hospital, Adelaide, Australia, 3Muscle and Nerve Laboratory, SA Pathology, Adelaide, Australia, 4Experimental Therapeutics Laboratory, University of South Australia, Adelaide, Australia, 5Immunology, Royal Adelaide Hospital, Adelaide, Australia, 6Royal Adelaide Hospital, Rheumatology Unit and University of Adelaide, Discipline of Medicine, Adelaide, Australia, 7Rheumatology, The Royal Adelaide Hospital, Adelaide, Australia

    Background/Purpose: Components of the innate immune system, such a High Mobility Group Box Protein 1 (HMGB1), may contribute to the initiation, perpetuation and resolution of…
  • Abstract Number: 287 • 2015 ACR/ARHP Annual Meeting

    Interleukin-35 in Idiopathic Inflammatory Myopathies

    Herman F. Mann1, Hana Hulejova2,3, Josef Zámecník4, Jaromir Hacek5, Mária Filková6, Olga Kryštufková7, J Vencovsky8 and Ladislav Senolt9, 1Department of Experimental Rheumatology, Institute of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague 2, Czech Republic, 2Institute of Rheumatology and Department of Rheumatology, Prague, Czech Republic, 31st Faculty of Medicine, Charles University, Prague, Prague, Czech Republic, 4Department of Pathology and Molecular Medicine, 2nd Medical School and University Hospital Motol, Charles University, Prague, Czech Republic, 5Department of Pathology and Molecular Medicine, 2nd Medical School and University Hospital Motol, Charles University, Prague, Czech Republic, Prague, Czech Republic, 6Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 7Institute of Rheumatology, Department of Rheumatology of the First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 8Institute of Rheumatology, Charles University, Prague, Czech Republic, 9Institute of Rheumatology, Prague, Czech Republic

    Background/Purpose: Interleukin-35 (IL-35) is a newly described heterodimeric cytokine that belongs to the IL-12 family and consists of p35 (IL-12a) and EBI3 (IL-27b) subunits. IL-35…
  • Abstract Number: 2070 • 2013 ACR/ARHP Annual Meeting

    Cytokine Profiles In Polymyositis and Dermatomyositis Complicated With Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Associated Interstitial Lung Disease Or Anti-Aminoacyl tRNA Synthetase Antibody-Associated Interstitial Lung Disease

    Takahisa Gono, Yasushi Kawaguchi, Hirotaka Kaneko, Yasuhiro Katsumata, Masanori Hanaoka, Sayuri Kataoka, Hidenaga Kawasumi, Kae Takagi, Hisae Ichida, Sayumi Baba, Yuko Okamoto, Yuko Ota and Hisashi Yamanaka, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan

    Background/Purpose: Polymyositis (PM) / dermatomyositis (DM) are often complicated with interstitial lung disease (ILD). In PM/DM, complication with ILD is associated with anti-aminoacyl-tRNA synthetase (ARS),…
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