Abstracts tagged "cytokines and metabolism"

Abstract Number: 1090 • 2016 ACR/ARHP Annual Meeting
CpG-Stimulated B Cells Require Glutaminolysis for Glycolysis, Mitochondrial Respiration, and Cytokine Production
Matthew Cheung¹, Dongyue Huang¹, Doujiao Wu², Edward Pearce³ and Alfred Kim¹, ¹Rheumatology, Washington University School of Medicine, Saint Louis, MO, ²Pathology & Immunology, Washington University School of Medicine, Saint Louis, MO, ³Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany
Background/Purpose: B cells contribute to disease pathophysiology through several mechanisms, including cytokine secretion. A wide variety of stimuli can activate B cells to produce cytokines…
Abstract Number: 1120 • 2016 ACR/ARHP Annual Meeting
Interleukin-1β Stabilize CXCL2 mRNA and Increase Its Expression
Satoshi Yamasaki, Yusuke Yoshida and Eiji Sugiyama, Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan
Background/Purpose: Changes in gene expression are closely related to inflammation and joint destruction in RA. Recently, it has been recognized that post-transcriptional regulation of the…

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