Abstract Number: 2900 • ACR/ARP Annual Meeting 2019
Interferon Signature Predicts Response to Tofacitinib in Haploinsufficiency of A20
Background/Purpose: The protein A20, encoded by TNFAIP3, represses signaling upstream of the inflammatory transcription factor nuclear factor (NF)-kB by regulating ubiquitination. Heterozygous loss-of-function mutations in…
ACR Meeting Abstracts