Abstracts tagged "cytokines and inflammatory arthritis"

Abstract Number: 175 • 2019 ACR/ARP Annual Meeting
Associations Between Circulating Cytokines and Incident Inflammatory Arthritis in an Anti-citrullinated Protein Antibody Positive Population
Kristen Polinski¹, Elizabeth Bemis ², M. Kristen Demoruelle ³, Marie Feser ⁴, LauraKay Moss ⁵, Jennifer Seifert ⁶, Michael Clare-Salzler ⁷, William Robinson ⁸, V. Michael Holers ⁶, Kevin Deane ⁴ and Jill Norris ⁹, ¹University of Colorado Denver, Aurora, CO, ²University of Colorado Denver, School of Public Health, Aurora, CO USA, Aurora, ³University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Aurora, ⁴University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Aurora, CO, ⁵University of Colorado Denver, Division of Rheumatology, Aurora, CO USA, Aurora, CO, ⁶University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Denver, ⁷Department of Pathology, University of Florida, Gainesville, FL, ⁸Stanford University, Stanford, CA, ⁹Colorado School of Public Health, Aurora
Background/Purpose: Elevated circulating cytokines are present years before the onset of rheumatoid arthritis (RA). We conducted a prospective cohort study in an at-risk population of…
Abstract Number: 2907 • 2014 ACR/ARHP Annual Meeting
Loss of microRNA-146a Exacerbates Inflammatory Arthritis
Victoria Saferding¹, Antonia Puchner², Eliana Goncalvesalves³, Birgit Niederreiter⁴, Silvia Hayer⁴, Gernot Schabbauer⁵, Marije Koenders⁶, Josef Smolen¹, Kurt Redlich³ and Stephan Blueml³, ¹Rheumatology, Medical University of Vienna, Vienna, Austria, ²Department of Rheumatology, Medical University of Vienna, Vienna, Austria, ³Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁵Vascular Biology and Thrombosis research, Medical University Vienna, Vienna, Austria, ⁶Rheumatology Research and Advanced Therapeutics, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands
Background/Purpose: MicroRNA (MiR-) 146a is a key regulator of the innate immune response and has also been shown to suppress cancer development in myeloid cells.…
Abstract Number: 770 • 2013 ACR/ARHP Annual Meeting
Suppressor Of Cytokine Signaling-3 Is a Critical Regulator Of gp130 Cytokine Signaling In Articular Chondrocytes
Xiao Liu^1,2, Kate E Lawlor^1,2, Ben A Croker¹ and Ian P Wicks^1,2,3, ¹Inflammation Division, Walter & Eliza Hall Institute of Medical Research, Parkville, Australia, ²Department of Medical Biology, University of Melbourne, Parkville, Australia, ³Department of Rheumatology, The Royal Melbourne Hospital, Melbourne, Australia
Background/Purpose: Cartilage damage is a key feature of inflammatory and degenerative arthritis and an important determinant of patient outcomes. Chondrocytes are the only cells in…

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