Abstracts tagged "cytokines and inflammasome activation"

Abstract Number: 2462 • 2015 ACR/ARHP Annual Meeting
Altered Expression of IL-10 Family Cytokines in Chronic Recurrent Multifocal Osteomyelitis Result in Enhanced Inflammasome Activation
Sigrun Hofmann¹, Angela Rösen-Wolff¹, Hermann Girschick², Henner Morbach³ and Christian Hedrich⁴, ¹Children's Hospital Dresden, Dresden, Germany, ²Children's Hospital, Berlin, Germany, ³Children's Hospital Würzburg, Würzburg, Germany, ⁴Pediatric Rheumatology and Immunology, Children's Hospital Dresden, Dresden, Germany
Background/Purpose: Chronic recurrent multifocal osteomyelitis (CRMO) is the most severe presentation of the autoinflammatory bone disorder chronic nonbacterial osteomyelitis (CNO). The pathophysiology of CNO remains…

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Abstracts tagged "cytokines and inflammasome activation"

Altered Expression of IL-10 Family Cytokines in Chronic Recurrent Multifocal Osteomyelitis Result in Enhanced Inflammasome Activation