Abstracts tagged "cytokines and immunoglobulin (IG)"

Abstract Number: 2529 • ACR/ARHP Annual Meeting 2012
Molecular Mechanism of IgG4 Class Switch Recombination in IgG4-Related Disease
Hiroto Tsuboi¹, Mana Iizuka¹, Hiromitsu Asashima¹, Sayaka Tsuzuki¹, Yuya Kondo¹, Akihiko Tanaka², Masafumi Moriyama², Isao Matsumoto¹, Seiji Nakamura² and Takayuki Sumida¹, ¹Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ²Faculty of Dental Science, Kyushu University, Fukuoka, Japan
Background/Purpose: IgG4-related disease (IgG4-RD) is a new disease entity characterized by high serum IgG4 levels, IgG4-positive plasmacytic infiltration and fibrosis in various organs. Although the…