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Abstracts tagged "CyTOF and systemic lupus erythematosus (SLE)"

  • Abstract Number: 3244 • ACR/ARHP Annual Meeting 2016

    Observations of Early and Late B Cell Alterations during Belimumab Treatment in Patients with Systemic Lupus Erythematosus Using Mass Cytometry (CyTOF)

    Ioannis Parodis1, Daniel Ramsköld1, Petter Brodin2, Agneta Zickert1, Lakshmikanth Tadepally2, Yang Chen2, Jaromir Mikes2, Adnane Achour2, Iva Gunnarsson1 and Vivianne Malmström1, 1Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, 2Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose:  Belimumab is a recombinant monoclonal antibody that inhibits soluble B lymphocyte stimulator (BLyS), also known as BAFF or TNFSF13B, and is approved for treating…

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