Abstracts tagged "cyclophosphamide and systemic lupus erythematosus (SLE)"

Abstract Number: 1640 • ACR/ARHP Annual Meeting 2014
Cyclophosphamide Diminishes Plasmablasts and Transitional B Cells and Suppresses Autocrine Production of B Cell Activating Factor of Tumor Necrosis Factor Family (BAFF) in These Cells in Patients with Systemic Lupus Erythematosus
Yuko Okamoto¹, Yasuhiro Katsumata¹, Yasushi Kawaguchi¹, Manabu Kawamoto¹, Takahisa Gono¹, Masanori Hanaoka¹, Tomoaki Higuchi¹, Hidenaga Kawasumi¹ and Hisashi Yamanaka², ¹Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ²Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan
Background/Purpose . B cell activating factor of tumor necrosis factor family (BAFF) is a positive regulator of B cell function and expressed in dendritic cells,…
Abstract Number: 1639 • ACR/ARHP Annual Meeting 2014
Serum Anti-Müllerian Hormone Levels in SLE Patients. the Disease Severity and Cyclophosphamide Reduce the Ovarian Reserve
Gerardo Marino¹, Laura Messuti¹, Maria Rita Gigante¹, Angela Barini², Silvia Canestri¹, Antonella Barini², Barbara Tolusso¹, Elisa Gremese¹ and Gianfranco Ferraccioli¹, ¹Division of Rheumatology, Institute of Rheumatology and Affine Sciences, Catholic University of the Sacred Heart, Rome, Italy, ²Department of Laboratory Medicine, Institute of Biochemistry and Clinical Biochemistry, Catholic University of The Sacred Heart, Rome, Italy
Background/Purpose . Systemic lupus erythematosus (SLE) predominantly affects women of childbearing age, can lead to severe organ involvement and may require prolonged immunosuppressive therapy. Anti-Müllerian Hormone is produced by the granulosa ovary cells and…