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Abstracts tagged "cyclophosphamide and systemic lupus erythematosus (SLE)"

  • Abstract Number: 1640 • 2014 ACR/ARHP Annual Meeting

    Cyclophosphamide Diminishes Plasmablasts and Transitional B Cells and Suppresses Autocrine Production of B Cell Activating Factor of Tumor Necrosis Factor Family (BAFF) in These Cells in Patients with Systemic Lupus Erythematosus

    Yuko Okamoto1, Yasuhiro Katsumata1, Yasushi Kawaguchi1, Manabu Kawamoto1, Takahisa Gono1, Masanori Hanaoka1, Tomoaki Higuchi1, Hidenaga Kawasumi1 and Hisashi Yamanaka2, 1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 2Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan

    Background/Purpose . B cell activating factor of tumor necrosis factor family (BAFF) is a positive regulator of B cell function and expressed in dendritic cells,…
  • Abstract Number: 1639 • 2014 ACR/ARHP Annual Meeting

    Serum Anti-Müllerian Hormone Levels in SLE Patients. the Disease Severity and Cyclophosphamide Reduce the Ovarian Reserve

    Gerardo Marino1, Laura Messuti1, Maria Rita Gigante1, Angela Barini2, Silvia Canestri1, Antonella Barini2, Barbara Tolusso1, Elisa Gremese1 and Gianfranco Ferraccioli1, 1Division of Rheumatology, Institute of Rheumatology and Affine Sciences, Catholic University of the Sacred Heart, Rome, Italy, 2Department of Laboratory Medicine, Institute of Biochemistry and Clinical Biochemistry, Catholic University of The Sacred Heart, Rome, Italy

    Background/Purpose . Systemic lupus erythematosus (SLE) predominantly affects women of childbearing age, can lead to severe organ involvement and may require prolonged immunosuppressive therapy. Anti-Müllerian Hormone is produced by the granulosa ovary cells and…
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