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Abstracts tagged "cyclooxygenase"

  • Abstract Number: 81 • ACR/ARHP Annual Meeting 2014

    Elevated Peripheral Blood Leukocyte Inflammatory Gene Expression in Radiographic Progressors with Symptomatic Knee Osteoarthritis: NYU and OAI Cohorts

    Mukundan Attur1, Alexander Statnikov2, Svetlana Krasnokutsky Samuels1, Virginia B. Kraus3, Joanne Jordan4, Braxton D. Mitchell5, Michelle Yau6, Jyoti Patel1, Constantin F. Aliferis2, Marc C. Hochberg7, Jonathan Samuels1 and Steven B. Abramson8, 1Rheumatology, NYU Langone Medical Center, New York, NY, 2Center for Health Informatics and Bioinformatics, NYU Langone Medical Center, New York, NY, 3Medicine/Rheumatology, Duke University Medical Center, Durham, NC, 4Thurston Arthritis Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 5Departments of Medicine and Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, MD, 6Epidemiology and Public Health, University of Maryland, Baltimore,, MD, 7Medicine, University of Maryland School of Medicine, Baltimore, MD, 8Dept of Rheumatology/Medicine, NYU Langone Medical Center, New York, NY

    Background/Purpose: We and others have demonstrated low grade inflammation exists in OA joint tissues, where it may contribute to disease pathogenesis. In the current studies…
  • Abstract Number: 2 • ACR/ARHP Annual Meeting 2012

    Microrna-558 Regulates the Expression of Cyclooxygenase-2 and IL-1beta Responses in Human Articular Chondrocytes

    Su Jin Park1, Eun-Jeong Cheon2 and Hyun Ah Kim2, 1Department of Internal Medicine, Hallym University Sacred Heart Hospital, Kyunggi, South Korea, 2Department of internal medicine, Hallym University Sacred Heart Hospital, Kyunggi, South Korea

    Background/Purpose: Osteoarthritis (OA) is a chronic degenerative joint disease in which multiple factors contribute to cartilage degradation. It is widely accepted that excess production of…

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