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Abstracts tagged "cutaneous manifestations and patient outcomes"

  • Abstract Number: 2843 • ACR/ARP Annual Meeting 2019

    Safety and Efficacy of Lenabasum at Week 68 in an Open-Label Extension of a Phase 2 Study of Lenabasum in Refractory Skin-Predominant Dermatomyositis (DM) Subjects

    Victoria Werth1, David Pearson 2, Joyce Okawa 2, Rui Feng 3, Josef Concha 2, Basil Patel 2, Emily Hejazi 2, Scott Constantine 4, Nancy Dgetluck 4 and Barbara White 4, 1Corporal Michael J. Crescenz VAMC, Philadelphia, PA, USA and Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA, Philadelphia, PA, 2Philadelphia Veteran Affairs Medical Center, University of Pennsylvania, Philadelphia, PA, 3University of Pennsylvania, Philadelphia, 4Corbus Pharmaceuticals, Norwood, MA

    Background/Purpose: Lenabasum is a rationally-designed preferential cannabinoid receptor type 2 agonist that activates resolution of innate immune responses to reduce tissue inflammation and fibrotic processes.…
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