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Abstracts tagged "CPPD"

  • Abstract Number: 1118 • ACR Convergence 2023

    The Nomenclature of Calcium Pyrophosphate Deposition (CPPD) Disease – Results of a Systematic Literature Review for the Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN) CPPD Nomenclature Project

    Silvia Sirotti1, Charlotte Jauffret2, Edoardo Cipolletta3, Daniele Cirillo4, Luca Ingrao4, Alessandro Lucia4, Antonella Adinolfi5, Debora Pireddu4, Emilio Filippucci6, Tristan Pascart2, Sara Tedeschi7, Robert Terkeltaub8, Nicola Dalbeth9 and Georgios Filippou1, 1IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy, 2Saint-Philibert Hospital, Lille Catholic University, Lille, France, 3Polytechnic University of Marche, Ancona, Italy, 4Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy, 5Rheumatology Unit, Grande Ospedale Metropolitano Niguarda, Milano, Italy, 6Polytechnic University of Marche, Jesi, Italy, 7Brigham and Women's Hospital, Boston, MA, 8University of California San Diego, San Diego, CA, 9University of Auckland, Auckland, New Zealand

    Background/Purpose: Despite prior attempts at standardising terminology of calcium pyrophosphate deposition (CPPD) disease (including the 2011 EULAR recommendations for CPPD terminology and diagnosis), many different…
  • Abstract Number: 1119 • ACR Convergence 2023

    Preliminary Descriptive Analysis of the RADIAL Cohort Study About the Prevalence and the Clinical Characteristics of Patients with CPPD in Daily Clinical Practice

    Silvia Sirotti1, Joao Madruga-Dias2, Antonella Adinolfi3, Garifallia Sakellariou4, Davide Rozza5, Greta Carrara5, Gianpiero Landolfi5, Carlo Alberto Scire5, Annamaria Iagnocco6 and Georgios Filippou1, 1IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy, 2Centro Hospitalar do Médio Tejo, NOVA Medical School, Lisbon, Portugal, 3Rheumatology Unit, Grande Ospedale Metropolitano Niguarda, Milano, Italy, 4Department of Internal Medicine and Therapeutics, Università di Pavia, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy, 5Società Italiana di Reumatologia, Epidemiology Research Unit, Milan, Italy, 6University of Turin, Roma, Italy

    Background/Purpose: The RADIAL study is aimed to evaluate the performance of a composite approach, based on clinical, laboratory and ultrasound (US) data in the differential…
  • Abstract Number: 1790 • ACR Convergence 2022

    Ultrasound Diagnosis of Calcium Pyrophosphate Crystal Deposition: Which Sites Should Be Scanned?

    Edoardo Cipolletta1, Erica Moscioni2, Silvia Sirotti3, Georgios Filippou4 and Emilio Filippucci5, 1Polytechnic University of Marche, Ancona, Italy, 2Polytechnic University of Marche, Jesi, Italy, 3Università degli Studi di Milano, Milano, Italy, 4Rheumatology Department, Luigi Sacco University Hospital, Siena, Italy, 5Polytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Jesi, Italy

    Background/Purpose: In recent years, ultrasonography (US) has emerged as an accurate and reliable tool for the diagnosis of calcium pyrophosphate (CPP) deposition disease (CPPD) in…
  • Abstract Number: 1791 • ACR Convergence 2022

    Point-of-Care Multi-Energy Photon-Counting CT for Earlier Non-Invasive Diagnosis of Gout and Calcium Pyrophosphate Deposition Disease

    Fabio Becce1, Anais Viry2, Damien Racine2, David Rotzinger1, Tristan Pascart3, Georgios Filippou4, Jérôme Damet2 and Lucia Gallego Manzano2, 1Lausanne University Hospital (CHUV), Lausanne, Switzerland, 2Institute of Radiation Physics, Lausanne, Switzerland, 3Groupement Hospitalier de l'Institut Catholique de Lille, Lomme, France, 4Rheumatology Department, Luigi Sacco University Hospital, Siena, Italy

    Background/Purpose: While the definitive diagnosis of gout and calcium pyrophosphate deposition disease (CPPD) is still based on the identification of characteristic crystals in synovial fluid…
  • Abstract Number: 1795 • ACR Convergence 2022

    Therapeutic Strategies for Patients with Chronic Manifestations of Calcium Pyrophosphate Deposition Disease

    Julien Damart1, Silvia Sirotti2, Mariano Andrès3, Edoardo Cipolletta4, Georgios Filippou5, Davide Carboni6, Emilio Filippucci7, Pilar Diez8, Abhishek Abhishek9, Augustin Latourte10, Hang-Korng Ea11, Sebastien Ottaviani12, Jean-Guillaume Letarouilly13, Renaud Desbarbieux14, Sahara Graf1, Laurène Norberciak1, Pascal Richette15 and Tristan Pascart16, 1Hôpital Saint-Philibert, Lomme, France, 2Università degli Studi di Milano, Milano, Italy, 3Dr Balmis Alicante General University Hospital-ISABIAL, Alicante, Spain, 4Polytechnic University of Marche, Ancona, Italy, 5Rheumatology Department, Luigi Sacco University Hospital, Siena, Italy, 6Luigi Sacco University, Milano, Italy, 7Polytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Jesi, Italy, 8Alicante University, Alicante, Spain, 9University of Nottingham, Nottingham, United Kingdom, 10Université de Paris, Paris, France, 11Lariboisière Hospital, Paris, France, 12Hopital Bichat-Claude Bernard, Paris, France, 13CHU Lille, Lille, France, 14Ch Boulogne-sur-Mer, Boulogne-sur-Mer, France, 15Department of Rheumatology, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France, 16Groupement Hospitalier de l'Institut Catholique de Lille, Lomme, France

    Background/Purpose: Calcium pyrophosphate deposition (CPPD) disease lacks recommendations on treatment strategies. This study reports on treatment modalities used in European tertiary hospitals for the management…
  • Abstract Number: 1813 • ACR Convergence 2022

    Patient-Reported Outcomes in CPPD Compared to Gout and Osteoarthritis

    Mary Grace Whelan1, Keigo Hayashi2 and Sara Tedeschi1, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Okayama, Japan

    Background/Purpose: Calcium pyrophosphate deposition (CPPD) disease prevalence is similar to gout and osteoarthritis (OA), yet CPPD outcomes research greatly lags behind these other forms of…
  • Abstract Number: 1817 • ACR Convergence 2022

    Acute Coronary Syndrome in Calcium Pyrophosphate Deposition Disease Patients: A Cross-sectional Study from the National Inpatient Sample

    Konstantinos Parperis1 and Bikash Bhattarai2, 1University of Cyprus Medical School, Nicosia, Cyprus, 2Valleywise Health, Phoenix, AZ

    Background/Purpose: Calcium pyrophosphate deposition disease (CPPD) is a common crystal-induced arthritis characterized by the deposition of calcium pyrophosphate crystals in the articular tissues. Acute CPP…
  • Abstract Number: 1819 • ACR Convergence 2022

    Calcium Pyrophosphate Deposition Disease Is Associated with an Increased Prevalence of Nephrolithiasis

    Alison Fernandes1, Yiran Jiang2, Katherine Sherman3, Ikechukwu Mbonu2, Rebecca Weiner2 and Ann Rosenthal2, 1Medical College of Wisconsin, Oconomowoc, WI, 2Medical College of Wisconsin, Milwaukee, WI, 3Zablocki VA Medical Center, Milwaukee, WI

    Background/Purpose: Calcium pyrophosphate deposition disease (CPDD) is a crystal arthropathy caused by calcium pyrophosphate (CPP) crystals. Individuals with CPDD also have increased risks for other…
  • Abstract Number: 1825 • ACR Convergence 2022

    Vascular Calcifications Adjacent to the Involved Joint of Patients Diagnosed with Calcium Pyrophosphate Crystal Arthritis – a Retrospective Observational Study

    Shay Brikman1, Amir Bieber2 and Reuven Mader1, 1Rheumatic Diseases Unit, Emek Medical Center, Afula, Israel, 2Emek Medical Center, Raanana, Israel

    Background/Purpose: Prior studies have shown an association between chondrocalcinosis (CC) and vascular calcifications. In this study, we aimed to assess the presence of vascular calcifications…
  • Abstract Number: 1913 • ACR Convergence 2022

    The Association of Radiographic Chondrocalcinosis with Localized Structural Outcomes in Knee OA: The Multicenter Osteoarthritis Study

    Jean Liew1, Ali Guermazi2, Mohamed Jarraya3, Na Wang1, David Felson2, Cora E. Lewis4, Michael Nevitt5, James Torner6, John A. Lynch7 and Tuhina Neogi1, 1Boston University School of Medicine, Boston, MA, 2Boston University, Boston, MA, 3Massachusetts General Hospital, Boston, MA, 4University of Alabama at Birmingham, Birmingham, AL, 5University of California at San Francisco, Orinda, CA, 6University of Iowa, Iowa City, IA, 7UCSF, San Francisco, CA

    Background/Purpose: Intra-articular (IA) mineralization due to calcium crystal deposition may contribute to OA pathology through inflammation, release of pro-catabolic factors, or altered cartilage biomechanical properties.…
  • Abstract Number: 1584 • ACR Convergence 2022

    Colchicine or Prednisone for the Treatment of Acute Calcium Pyrophosphate Deposition Arthritis: A Multicenter Randomized Controlled Trial

    Tristan Pascart1, Pierre Robinet2, Sebastien Ottaviani3, Remi Leroy4, Nicolas Segaud5, Aurore Pacaud2, Hélène Luraschi2, Thibault Rabin2, Agathe Grandjean2, Xavier Deplanque6, Pierre Maciejasz6, Fabien Visade2, Alexandre Mackowiak2, Nicolas Baclet6, Antoine Lefebvre2, Jean-François Budzik2, Thomas Bardin7, Pascal Richette8, Laurène Norberciak2, Vincent Ducoulombier2 and Eric Houvenagel1, 1Groupement Hospitalier de l'Institut Catholique de Lille, Lomme, France, 2Hôpital Saint-Philibert, Lomme, France, 3Hopital Bichat-Claude Bernard, Paris, France, 4Centre Hospitalier de Dunkerque, Dunkerque, France, 5Centre Hospitalier d'Armentières, Armentières, France, 6Hôpital Saint-Vincent-de-Paul, Lille, France, 7Hôpital Lariboisiere, Paris, France, 8Department of Rheumatology, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France

    Background/Purpose: Treatment of acute CPP arthritis mainly relies on expert opinion, as there are no trials that assessed the efficacy of anti-inflammatory drugs, despite the…
  • Abstract Number: 0172 • ACR Convergence 2021

    Assessing Relevant Joints for Monitoring CPPD Diseases: A Systematic Literature Review of Imaging Techniques by the OMERACT Ultrasound – CPPD Subgroup

    Antonella Adinolfi1, Silvia Sirotti2, Garifallia Sakellariou3, Edoardo Cipolletta4, Emilio Filippucci5, Francesco Porta6, Piercarlo Sarzi-Puttini7, Carlo Alberto Scire8, Helen Keen9, Peter Mandl10, Carlos Pineda11, Lene Terslev12, Maria Antonietta D'Agostino13, Nemanja Damjanov14, Annamaria Iagnocco15 and Georgios Filippou16, 1Rheumatology Unit, Grande Ospedale Metropolitano Niguarda, Milan, Italy, 2Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy, 3Division of Rheumatology, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy, 4Rheumatology Unit, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy, 5Rheumatology Unit, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Jesi, Italy, 6INS, Institute of Neurosciences, Florence, Italy, 7L.Sacco University Hospital, Milano, Italy, 8SIR Epidemiology, Research Unit, Pavia, Italy, 9University of Western Australia, Daglish, Australia, 10Medical University of Vienna, Vienna, Austria, 11Instituto Nacional de Rehabilitacion, Mexico City, Federal District, Mexico, 12Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen University, Glostrup, Denmark, 13Rheumatology, Fondazione Policlinico Universitario “Gemelli”, IRCCS, Rome, Italy, 14University of Belgrade School of Medicine, Institute of Rheumatology, Belgrade, Serbia, 15University of Turin, Roma, Italy, 16Rheumatology Department, Luigi Sacco University Hospital, Siena, Italy

    Background/Purpose: Imaging has been extensively used for the diagnosis of Calcium Pyrophosphate Deposition Disease (CPPD) but the exact prevalence of joint calcifications at imaging in…
  • Abstract Number: 0670 • ACR Convergence 2021

    Hemochromatosis Is Associated with CPPD Through Iron’s Effect on Bone

    Jennifer Velasco, Claudia Gohr, Elizabeth MItton-Fitzgerald and Ann Rosenthal, Medical College of Wisconsin, Milwaukee, WI

    Background/Purpose: Hemochromatosis (HH) is one of the strongest known risk factors for calcium pyrophosphate (CPP) crystal deposition. The pathogenic mechanisms causing CPP crystal formation in…
  • Abstract Number: 1181 • ACR Convergence 2021

    Self Directed Learning Among Internal Medicine Residents: Incorporating a New Teaching Module on Calcium Pyrophosphate Deposition in the Rheumatology Curriculum

    Bassel Bou Dargham, Abhishek Nandan, Beth Rubinstein and Stamatina Danielides, Virginia Commonwealth University, Richmond, VA

    Background/Purpose: Medical knowledge is evolving at a fast pace, and it is important for medical students and residents to develop self-directed learning skills that will…
  • Abstract Number: 1582 • ACR Convergence 2021

    Diagnostic Accuracy and Reliability of Conventional Radiography of the Knee in Calcium Pyrophosphate Deposition Disease by Using New Definitions: An Ancillary Study of the OMERACT Ultrasound – CPPD Group

    Silvia Sirotti1, Fabio Becce2, Luca Maria Sconfienza3, Carlos Pineda4, Marwin Gutierrez5, Teodora Serban6, Daryl MacCarter7, Antonella Adinolfi8, Anna Scanu9, Carlo Alberto Scire10, Ingrid Moller11, Esperanza Naredo12, Piercarlo Sarzi-Puttini13, Abhishek Abhishek14, Hyon K. Choi15, Nicola Dalbeth16, Sara Tedeschi17, Maria-Antonietta D'Agostino18, Nemanja Damjanov19, Helen Keen20, Lene Terslev21, Annamaria Iagnocco22 and Georgios Filippou23, 1Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy, 2Lausanne University Hospital, Lausanne, Switzerland, 3Department of Biomedical Sciences for Health, Università Degli Studi di Milano, Milan, Italy, 4Instituto Nacional de Rehabilitacion, Mexico City, Federal District, Mexico, 5Division of Musculoskeletal and Rheumatic Diseases, Instituto Nacional de Rehabilitacion, Mexico City, Mexico, 6Ospedale La Colletta, ASL3 Genovese, Genoa, Italy, 7Rheumatology Department, North Valley Hospital, Whitefish, MT, 8Rheumatology Unit, Grande Ospedale Metropolitano Niguarda, Milan, Italy, 9Department of Medicine-DIMED, Rheumatology Unit, University of Padova, Padoa, Italy, 10SIR Epidemiology, Research Unit, Pavia, Italy, 11University of Barcelona, Barcelona, Spain, 12Department of Rheumatology and Joint and Bone Research Unit, Hospital Fundación Jiménez Díaz and Autónoma University, Madrid, Spain, 13Rheumatology Department, Luigi Sacco University Hospital, Milano, Italy, 14University of Nottingham, Nottingham, United Kingdom, 15Massachusetts General Hospital, Lexington, MA, 16University of Auckland, Auckland, New Zealand, 17Brigham and Women's Hospital, Boston, MA, 18Rheumatology Department, Università Cattolica del Sacro Cuore, Policlinico Universitario Agostino Gemelli IRCSS, Rome, Italy, 19University of Belgrade School of Medicine, Institute of Rheumatology, Belgrade, Serbia, 20University of Western Australia, Daglish, Australia, 21Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen University, Glostrup, Denmark, 22University of Turin, Roma, Italy, 23Rheumatology Department, Luigi Sacco University Hospital, Siena, Italy

    Background/Purpose: Conventional Radiography (CR) has been widely used in Calcium Pyrophosphate Deposition Disease (CPPD) and is considered an important tool for the diagnosis. However, there…
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