Abstracts tagged "CPPD"

Abstract Number: 0269 • ACR Convergence 2024
Delphi Survey to Establish Consensus on the OMERACT Core Domain Set for Long-Term Studies of Calcium Pyrophosphate Deposition Disease
Yiling Zhang¹, Sara Tedeschi², Abhishek Abhishek³, Owen Hensey⁴, David Grossberg⁵, Ken Cai⁶, Beverley Shea⁷, Jasvinder Singh⁸, Robin Christensen⁹, Teodora Serban¹⁰, Edoardo Cipolletta¹¹, Konstantinos Parperis¹², César Díaz¹³, Geraldine McCarthy¹⁴, Fabio Becce¹⁵, Tamer A Gheita¹⁶, Silvia Sirotti¹⁷, Sara Nysom Christiansen¹⁸, Luis Coronel Tarancon¹⁹, Lisa Stamp²⁰, Yousra H Abdel-Fattah²¹, Tristan Pascart²², Georgios Filippou¹⁷, Lih En Hong²³, John FitzGerald²⁴ and Nicola Dalbeth¹, ¹University of Auckland, Auckland, New Zealand, ²Brigham and Women's Hospital, Boston, MA, ³University of Nottingham, Nottingham, United Kingdom, ⁴OMERACT patient research partner, Dublin, Ireland, ⁵OMERACT patient research partner, Maryland, ⁶Westmead Hospital, Sydney, New South Wales, Australia, ⁷Ottawa Hospital Research Institute, Ottawa, ON, Canada, ⁸Baylor College of Medicine, Birmingham, AL, ⁹Musculoskeletal Statistics Unit, The Parker Institute, Copenhagen, Denmark, ¹⁰Ospedale La Colletta, Bucharest, Romania, ¹¹Polytechnic University of Marche, Ancona, Italy, ¹²University of Cyprus Medical School, Nicosia, Cyprus, ¹³Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ¹⁴Mater Misericordiae University Hospital, Dublin, Ireland, ¹⁵Lausanne University Hospital (CHUV), Lausanne, Switzerland, ¹⁶Rheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt, ¹⁷IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy, ¹⁸Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark., Glostrup, Denmark, ¹⁹Image and Technics Unit, Department of Rheumatology. Hospital Universitari Vall d’Hebron, Barcelona, Spain, ²⁰University of Otago, Christchurch, Christchurch, New Zealand, ²¹Alexandria University, Alexandria, Egypt, ²²Lille Catholic University, Lille, France, ²³Royal Adelaide Hospital, Unley Park, South Australia, Australia, ²⁴UCLA, Los Angeles, CA
Background/Purpose: To agree on important domains for the Outcome Measures in Rheumatology (OMERACT) core domain set for long-term studies of calcium pyrophosphate deposition (CPPD) disease.Methods:…
Abstract Number: 0270 • ACR Convergence 2024
Longitudinal Patterns of C-Reactive Protein Values in Calcium Pyrophosphate Deposition (CPPD) Disease
Muneet Gill, Hongshu Guan, Jamie Collins and Sara Tedeschi, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Calcium pyrophosphate deposition (CPPD) disease is a crystalline arthritis affecting older adults. Systemic inflammation occurs during flares of acute calcium pyrophosphate (CPP) crystal arthritis…
Abstract Number: 0272 • ACR Convergence 2024
Calcifications of the Transverse Ligament of the Atlas in Patients Diagnosed with Calciumpyrophosphate Crystal Arthritis – a Retrospective Observational Study
Shay Brikman¹, Noga Shabshin² and Amir Bieber³, ¹Emek Medical Center, Afula, Israel, ²Emek Medical Center, Clalit Health Services, Afula, Israel, ³Emek Medical Center, Clalit Health Services, Raanana, Israel
Background/Purpose: Chondrocalcinosis (CC) is commonly detected on X-ray films of the knee, wrist, and symphysis pubis. Calcium pyrophosphate (CPP) deposition disease is sometimes associated with…
Abstract Number: 0279 • ACR Convergence 2024
Macrophage Intracellular Fates of Monosodium Urate and Calcium Pyrophosphate Crystals: Phagocytosis, Exchanged/expulsion and Dissolution of Crystals
Charles Leroy¹, Nghia Pham², François Brial³, Brenda Kischkel⁴, gwénaêlle Jayat⁵, Elena Ishow⁶, Christèle Combes⁷, Leo Joosten⁴, Augustin Latourte⁸, Pascal Richette⁹ and Hang-Korng Ea¹⁰, ¹Inserm 1132 / Université Paris Cité, levallois-perret, France, ²INSERM 1132, BIOSCAR, Lariboisière hospital, Paris, France, ³Inserm 1132/ Université Paris Cité, Paris, France, ⁴Radboudumc, Nijmegen, Netherlands, ⁵Université Paris cité / Inserm 1132, paris, France, ⁶Université de Nantes / Ceisam, Nantes, France, ⁷INP-ENSIACET, Toulouse, France, ⁸AP-HP, Paris, France, ⁹Lariboisière Hospital, Paris, France, ¹⁰Université Paris Cité, INSERM UMR 1132 BIOSCAR, Paris, France
Background/Purpose: Gout, due to the presence of monosodium urate crystals (MSU) and calcium pyrophosphate (CPP) crystal deposition disease are both responsible for recurrent inflammation flares.…
Abstract Number: 0284 • ACR Convergence 2024
Identification of Calcium Pyrophosphate Deposition Using Ultrasonography in Patients with a Suspected Diagnosis of Seronegative Rheumatoid Arthritis
Joanna Potera¹, Angelo Gaffo², Alvin Day³, Mariana Urquiaga² and Amanda Alexander⁴, ¹University of Alabama at Birmingham, Irondale, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³Dept. of Veterans Affairs, Lexington, SC, ⁴University of Alabama at Birmingham, Homewood, AL
Background/Purpose: Calcium pyrophosphate deposition disease is a common condition that can cause chronic polyarticular inflammatory joint disease, which sometimes resembles rheumatoid arthritis. Misdiagnosis is especially…
Abstract Number: 1109 • ACR Convergence 2024
Differences Between Correlation and Causal Inference in Detecting Predictors of Undefined Crystal Arthropathy in Women
Laura Scagnellato¹, Antonio Collesei², Sonia farah³, Carlomaurizio Montecucco⁴, Francesca Oliviero⁵, Bernd raffeiner⁶, Marta favero⁵, Amelia Damasco⁵, doria Andrea⁵, Fausto Salaffi³ and Roberta Ramonda⁷, and SIR Study Group on Crystal Arthropaties, ¹Rheumatology Unit, University of Padova, Padova, Italy, ²IRCCS Istituto Oncologico Veneto IOV, Padova, Italy, ³Polytechnic University of Marche, Jesi (AN), Italy, ⁴IRCCS policlinico S. Matteo foundation, University of Pavia, Pavia, Italy, ⁵University of Padova, Padova, Italy, ⁶General Hospital of Bolzano, Bolzano, Italy, ⁷Rheumatology Unit, University of Padova, Italy, Padova, Italy
Background/Purpose: Crystal arthropaties, including gout and calcium pyrophosphate deposition disease (CPPD), are prevalent and burdensome conditions. The ALLSTAR model allows the identification of reliable causal,…
Abstract Number: 1340 • ACR Convergence 2024
Characteristics and Long-term Outcomes of Patients with Rheumatoid Arthritis and Concurrent Calcium Pyrophosphate Deposition Disease
Natalie Schanzer¹, Ted Mikuls², Bryant England², Katherine Wysham³, Jorge Rojas⁴, Sauer brian⁵, Beth Wallace⁶, Rachel Elam⁷, Andreas Reimold⁸, Gail Kerr⁹, John Richards¹⁰, Gary Kunkel¹¹, Iris Lee¹², Isaac Smith¹³, Paul Monach¹⁴, grant Cannon¹⁵ and Joshua Baker¹⁶, ¹Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, ²University of Nebraska Medical Center, Omaha, NE, ³VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA, ⁴Seattle VA, Mexico, Mexico, ⁵Salt Lake City VA/University of Utah, Salt Lake City, UT, ⁶Michigan Medicine, VA Ann Arbor Healthcare System, Ann Arbor, MI, ⁷Augusta University, Evans, GA, ⁸Dallas VA Medical Center, Dallas, TX, ⁹Washington DC VAMC/Georgetown and Howard Universities, Washington, DC, ¹⁰Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, ¹¹University of Utah and George E Wahlen VAMC, Salt Lake City, UT, ¹²Washington University in St Louis, Saint Louis, MO, ¹³Duke University Hospital, Durham, NC, ¹⁴VA Boston Healthcare System, Boston, MA, ¹⁵University of Utah and Salt Lake City VA, Salt Lake City, UT, ¹⁶University of Pennsylvania, Philadelphia, PA
Background/Purpose: Calcium pyrophosphate deposition disease (CPPD) is a common crystalline arthritis that can both present alongside rheumatoid arthritis (RA) and, given its similar pattern of…
Abstract Number: 2562 • ACR Convergence 2024
Efficacy and Safety of Tocilizumab in the Treatment of Chronic Inflammatory Forms of CPPD: Retrospective Study of 55 Cases
Sophie Carrabin¹, Margaux Houze², Charlotte Jauffret³, Thomas Bardin⁴, Hang Korng Ea⁴, Frédéric Lioté⁴, Pascal Richette⁵, Tristan Pascart² and Augustin Latourte⁶, ¹Hôpital Lariboisière APHP.Nord, Paris, Paris, France, ²Lille Catholic University, Lille, France, ³Lille Catholic University, Lille, Nord-Pas-de-Calais, France, ⁴Hôpital Lariboisière APHP.Nord, Paris, France, ⁵Lariboisière Hospital, Paris, France, ⁶AP-HP, Paris, France
Background/Purpose: Calcium pyrophosphate deposition disease (CPPD) is a heterogeneous disease that can manifest as acute or chronic arthritis. Treatment options for chronic forms of the…
Abstract Number: 1115 • ACR Convergence 2023
EULAR Recommendations for the Use of Imaging in the Diagnosis and Management of Crystal-induced Arthropathies in Clinical Practice
Peter Mandl¹, Maria-Antonietta D'Agostino², Victoria Navarro-Compán³, Irina Gessl¹, Garifallia Sakellariou⁴, Abhishek Abhishek⁵, Fabio Becce⁶, Nicola Dalbeth⁷, Hang-Korng Ea⁸, Emilio Filippucci⁹, Hilde Berner Hammer¹⁰, Annamaria Iagnocco¹¹, Annette De Thurah¹², Esperanza Naredo¹³, Sebastien Ottaviani¹⁴, Tristan Pascart¹⁵, Fernando Perez-Ruiz¹⁶, Irene Pitsillidou¹⁷, Fabian Proft¹⁸, Juergen Rech¹⁹, Wolfgang Schmidt²⁰, Luca Sconfienza²¹, Lene Terslev²², Brigitte Wildner²³, Pascal Zufferey²⁴ and Georgios Filippou²⁵, ¹Department of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Universita Cattolica del Sacro Cuore Rome, Courbevoie, France, ³Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, ⁴Department of Internal Medicine and Therapeutics, Università di Pavia, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy, ⁵University of Nottingham, Nottingham, United Kingdom, ⁶Lausanne University Hospital (CHUV), Lausanne, Switzerland, ⁷University of Auckland, Auckland, New Zealand, ⁸Hôpital Lariboisière, APHP-Nord, Service de Rhumatologie, Université de Paris Cité, Paris, France, ⁹Polytechnic University of Marche, Jesi, Italy, ¹⁰Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway AND University of Oslo, Faculty of Medicine, Oslo, Norway, ¹¹University of Turin, Roma, Italy, ¹²Aarhus University Hospital, Aarhus, Denmark, ¹³Hospital Fundación, Madrid, Spain, ¹⁴Assistance Publique Hopitaux de Paris, Paris, France, ¹⁵Department of Rheumatology, Saint-Philibert Hospital, Lille Catholic University, Lille, France, ¹⁶Rheumatology Division, Osakidetza, OSI-EE Cruces, Cruces University Hospital, Barakaldo, Spain, ¹⁷EULAR Patient Research Partner, Executive Secretary of Cyprus League Against Rheumatism, Nicosia, Cyprus, ¹⁸Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ¹⁹University Clinic Erlangen, Erlangen, Germany, ²⁰Rheumatology, Immanuel Krankenhaus Berlin, Medical Centre for Rheumatology Berlin-Buch, Berlin, Germany, ²¹Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano AND IRCCS Istituto Ortopedico Galeazzi, 20161, Milan, Italy, ²²Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, ²³University Library, Medical University of Vienna, Vienna, Austria, ²⁴Rheumatology Department, University of Lausanne, CHUV, Lausenne, Switzerland, ²⁵IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy
Background/Purpose: The multifaceted clinical presentation in crystal-induced arthropathies (CiA) poses challenges to imaging. Our goal was to formulate evidence-based recommendations on the use of imaging…
Abstract Number: 1118 • ACR Convergence 2023
The Nomenclature of Calcium Pyrophosphate Deposition (CPPD) Disease – Results of a Systematic Literature Review for the Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN) CPPD Nomenclature Project
Silvia Sirotti¹, Charlotte Jauffret², Edoardo Cipolletta³, Daniele Cirillo⁴, Luca Ingrao⁴, Alessandro Lucia⁴, Antonella Adinolfi⁵, Debora Pireddu⁴, Emilio Filippucci⁶, Tristan Pascart², Sara Tedeschi⁷, Robert Terkeltaub⁸, Nicola Dalbeth⁹ and Georgios Filippou¹, ¹IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy, ²Saint-Philibert Hospital, Lille Catholic University, Lille, France, ³Polytechnic University of Marche, Ancona, Italy, ⁴Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy, ⁵Rheumatology Unit, Grande Ospedale Metropolitano Niguarda, Milano, Italy, ⁶Polytechnic University of Marche, Jesi, Italy, ⁷Brigham and Women's Hospital, Boston, MA, ⁸University of California San Diego, San Diego, CA, ⁹University of Auckland, Auckland, New Zealand
Background/Purpose: Despite prior attempts at standardising terminology of calcium pyrophosphate deposition (CPPD) disease (including the 2011 EULAR recommendations for CPPD terminology and diagnosis), many different…
Abstract Number: 1119 • ACR Convergence 2023
Preliminary Descriptive Analysis of the RADIAL Cohort Study About the Prevalence and the Clinical Characteristics of Patients with CPPD in Daily Clinical Practice
Silvia Sirotti¹, Joao Madruga-Dias², Antonella Adinolfi³, Garifallia Sakellariou⁴, Davide Rozza⁵, Greta Carrara⁵, Gianpiero Landolfi⁵, Carlo Alberto Scire⁵, Annamaria Iagnocco⁶ and Georgios Filippou¹, ¹IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy, ²Centro Hospitalar do Médio Tejo, NOVA Medical School, Lisbon, Portugal, ³Rheumatology Unit, Grande Ospedale Metropolitano Niguarda, Milano, Italy, ⁴Department of Internal Medicine and Therapeutics, Università di Pavia, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy, ⁵Società Italiana di Reumatologia, Epidemiology Research Unit, Milan, Italy, ⁶University of Turin, Roma, Italy
Background/Purpose: The RADIAL study is aimed to evaluate the performance of a composite approach, based on clinical, laboratory and ultrasound (US) data in the differential…
Abstract Number: 0230 • ACR Convergence 2023
Looking Beyond Infections in Job Syndrome: Peripheral Calcium Pyrophosphate Deposition Disease in a Cohort of Patients with Job Syndrome
Sandra Ogbonnaya-Whittlesey¹, Ecem Sevim¹, Dale Kobrin¹, sarthak gupta², Paul DeMarco³ and Alexandra Freeman⁴, ¹NIH/NIAMS, Bethesda, MD, ²Lupus Clinical Trials Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NIH), Bethesda, MD, ³National Institute of Arthritis and Musculoskeletal and Skin Disease, Bethesda, MD, ⁴NIH/NIAID, Bethesda, MD
Background/Purpose: Job syndrome or hyperimmunoglobulin E syndrome is an immunodeficiency for which the clinical picture consists largely of frequent infectious complications of the lungs, sinuses,…
Abstract Number: 0235 • ACR Convergence 2023
Fractures in Patients with Acute CPP Crystal Arthritis versus Matched Comparators in a Large Cohort Study
Sara Tedeschi¹, Keigo Hayashi¹, Ann Rosenthal², Javier Marrugo¹, Sho Fukui¹, Ellen Gravallese³ and Daniel Solomon¹, ¹Brigham and Women's Hospital, Boston, MA, ²Medical College of Wisconsin, Milwaukee, WI, ³Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Calcium pyrophosphate deposition (CPPD) disease was positively associated with osteopenia in two large cross-sectional studies, but risk of fractures has not been evaluated. We…
Abstract Number: 0250 • ACR Convergence 2023
Validation of Singe-Shot Computational Polarized Microscopy for Crystal Analysis of Synovial Fluid
John FitzGerald¹, Tairan Liu¹, Chesca Barrios¹, Bijie Bai¹, Geraldine McCarthy², Ann Rosenthal³ and Aydogan Ozcan¹, ¹University of California Los Angeles, Los Angeles, CA, ²Mater Misericordiae University Hospital, Dublin, Ireland, ³Medical College of Wisconsin, Milwaukee, WI
Background/Purpose: The gold standard for diagnosis of crystal arthritis relies on the identification of either monosodium urate (MSU) or calcium pyrophosphate (CPP) crystals in synovial…
Abstract Number: 0318 • ACR Convergence 2023
The Association of CT-Detected Intra-Articular Mineralization with MRI-Detected Effusion-Synovitis and Hoffa’s Synovitis in Knee OA: The Multicenter Osteoarthritis Study
Jean Liew¹, Gabriela Rabasa¹, Mohamed Jarraya², Ali Guermazi¹, David Felson¹, Beth Lewis³, John Lynch⁴, Michael Nevitt⁴, James Torner⁵ and Tuhina Neogi⁶, ¹Boston University, Boston, MA, ²Massachusetts General Hospital, Boston, MA, ³University of Alabama at Birimingham, Birmingham, AL, ⁴University of California San Francisco, San Francisco, CA, ⁵University of Iowa, Iowa City, IA, ⁶Boston University School of Medicine, Boston, MA
Background/Purpose: Intra-articular (IA) deposition of calcium crystals (chondrocalcinosis), is common in knee OA. While calcium crystals can cause inflammatory arthritis, their contribution to joint inflammation…

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