ACR Meeting Abstracts

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Abstracts tagged "COVID-19"

  • Abstract Number: 0304 • ACR Convergence 2023

    Incidence of Disease Flares Following COVID-19 Vaccination in a Diverse Idiopathic Inflammatory Myopathy Cohort

    Hillary Weisleder1, Ana Valle1, Xianhong Xie2 and Shereen Mahmood3, 1Montefiore Medical Center, Bronx, NY, 2Albert Einstein College of Medicine, Bronx, NY, 3Albert Einstein College of Medicine / Montefiore Medical Center, New York, NY

    Background/Purpose: Autoimmune activation in the setting of vaccination against coronavirus disease 2019 (COVID-19) is a well-documented phenomenon in the medical literature. For patients with idiopathic…
  • Abstract Number: 1297 • ACR Convergence 2023

    COVID-19 Vaccination-related Delayed Adverse Events Among Patients with Rheumatoid Arthritis: Results from the COVAD Study

    Mrinalini Dey1, Bohdana Doskaliuk2, Ioannis Parodis3, Julius Lindblom3, Chris Wincup4, Mrudula Joshi5, Dey Dzifa6, Esha Kadam7, Parikshit Sen8, Samuel Shinjo9, Arvind Nune10, Nelly Ziade11, Yi-Ming Chen12, Lisa Traboco13, CARLOS ENRIQUE TORO GUTIERREZ14, COVAD Study Group15, Rohit Aggarwal16, Vikas Agarwal17, Latika Gupta18 and Elena Nikiphorou19, 1Queen Elizabeth Hospital, London, United Kingdom; University of Liverpool, Liverpool, United Kingdom, 2SHEI "Ivano-Frankivsk national medical university", Ivano-Frankivsk, Ukraine, 3Karolinska Institutet, Stockholm, Sweden, 4King's College Hospital, London, United Kingdom, 5Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, 6Department of Medicine and Therapeutics, University of Ghana School of Medicine and Dentistry, College of Health Sciences, Korle-Bu, Accra, Ghana, 7Seth Gordhandhas Sunderdas Medical College and King Edwards Memorial Hospital, Mumbai, India, 8Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi-110002, India., Dalhi, India, 9Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil, 10Southport & Ormskirk NHS Foundation Trust, Liverpool, United Kingdom, 11Saint-Joseph University, Beirut, Lebanon, 12Taichung Veterans General Hospital, Taichung, Taiwan, 13University of the Philippines - Manila, St Luke's Medical Center - Bonifacio Global City, Paranaque, Manila, Philippines, 14Centro de Estudios de Reumatología y Dermatología SAS, Cali, Colombia, 15-, -, 16University of Pittsburgh, Pittsburgh, PA, 17Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, 18Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom, 19King's College London, London, United Kingdom

    Background/Purpose: COVID-19 vaccines have been proven to be safe in the healthy population. Data on longer-term AEs in people with autoimmune diseases (AIDs), including rheumatoid…
  • Abstract Number: 1813 • ACR Convergence 2023

    Assessing Immunogenicity of SARS-CoV-2 Vaccine Neoantigen S1 in Autoimmune Rheumatic Disease Patients: A Study on Cellular and Humoral Responses

    Inés Pérez Sancristóbal1, Maria Paula Alvarez Hernandez1, kauzar Mohamed Mohamed2, Maria Rodriguez Laguna1, Cristina Martinez3, Esther Toledano3, Dalifer Freites4, Benjamin Fernandez1, María Rodero3, Cecilia Bravo3, Antonia Rodrígez de la Peña5, Silvia Sanchez - Ramon5, Gloria mato Chain6 and Gloria Candelas1, 1Hospital Clinico San Carlos, Madrid, Spain, 2Department of Immunology, Hospital Clínico San Carlos, Madrid, Spain, 3Hospital Clinico San Carlos, Rheumatology Deparment, Madrid, Spain, 4Hospital Clínico San Carlos, Madrid, Spain, 5Department of Clinical Immunology, IML and IdSSC, Hospital Clínico San Carlos, Madrid, Spain, 6Department of Preventive Medicine, Hospital Clínico San Carlos, Madrid, Spain

    Background/Purpose: Data on cellular and humoral immunogenicity triggered by SARS-CoV-2 vaccines in patients with autoimmune rheumatic diseases (ARD) are limited. While current vaccine efforts have…
  • Abstract Number: 2131 • ACR Convergence 2023

    Time-course Analysis from the First Wave to Early 2023 in Critically Ill Patients with Novel Coronavirus Infection in Rheumatoid Arthritis

    MASAOMI YAMASAKI, Shin-Yokohama Arthritis and Rheumatology Clinic, Yokohama, Japan

    Background/Purpose: We analyzed trends in the incidence and severity of novel coronavirus disease (COVID-19) from the first wave to early 2023 in patients with rheumatoid…
  • Abstract Number: 0215 • ACR Convergence 2023

    Effectiveness of Three Doses of SARS-CoV-2 Vaccines in Brazilian Patients with Systemic Vasculitides: Preliminary Results of a Real-life Prospective Cohort

    Erika Biegelmeyer1, Mariana Freitas de Aguiar1, Priscila Dias Cardoso Ribeiro1, Ketty Lysie Libardi Lira Machado2, Maria da Penha Gomes Gouveia2, Camila Maria Paiva França Telles3, Samuel Elias Basualto Dias3, Natália Sarzi Sartori4, Thaís Evelyn Karnopp5, Vanessa de Oliveira Magalhães1, Flávia Maria Matos Melo Campos Peixoto1, Laiza Hombre Dias2, Débora Marques Veghini2, Rodrigo Vieira de Rezende6, Katia Lino Baptista6, Ana Karla Guedes de Melo7, Vitor Alves Cruz8, Maria Cecília Dias Corrêa9, Adriana Maria Kakehasi10, Rejane Maria Rodrigues de Abreu Vieira11, Valderilio Feijó Azevedo12, Olindo Assis Martins-Filho13, Charlles Heldan de Moura Castro1, Ricardo Xavier14, Andréa Teixeira-Carvalho13, Viviane Angelina de Souza9, Odirlei André Monticelo15, Marcelo Pinheiro16, Edgard Torres dos Reis Neto1, Emilia Sato1, Gilda Ferreira17, Gecilmara Pileggi18, Valeria Valim19 and Alexandre wagner Silva de Souza20, 1Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil, 2Hospital Universitário Cassiano Antônio Moraes da Universidade Federal do Espírito Santo (HUCAM-UFES), Vitória, Brazil, 3Universidade Federal do Amazonas, Manaus, Brazil, 4Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, 5Post-Graduate Program in Medical Sciences, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, 6Universidade Federal Fluminense, Niterói, Brazil, 7Hospital Universitário Lauro Wanderley, Universidade Federal da Paraíba, João Pessoa, Brazil, 8Universidade Federal de Goiás, Goiânia, Brazil, 9Universidade Federal de Juiz de Fora, Juiz de Fora, Brazil, 10Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil, 11Universidade de Fortaleza (UNIFOR), Fortaleza, Brazil, 12Department of Internal Medicine, Hospital de Clínicas at the Federal University of Paraná, Curitiba, Paraná, Brazil, 13Instituto Renè Rachou, Fundação Oswaldo Cruz (FIOCRUZ-Minas), Belo Horizonte, Brazil, 14Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, 15Division of Rheumatology, Department of Internal Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, 16UNIFESP/ EPM, São Paulo, Brazil, 17Federal University of Minas Gerais, Belo Horizonte, Brazil, 18UNIFESP, Ribeirão Preto, Brazil, 19Universidade Federal do Espírito Santo, Vitória, Brazil, 20Division of Rheumatology, Medical School, Universidade Federal de São Paulo, São Paulo, Brazil

    Background/Purpose: Vaccine platforms, number of doses, and immunosuppressive drugs can influence the immunogenicity after SARS-CoV-2 vaccination in individuals with immune-mediated rheumatic diseases. Considering the heterogeneity…
  • Abstract Number: 0412 • ACR Convergence 2023

    COVID Antibody Response to Third Dose Anti-SARS-COV2 mRNA Vaccine in Patients with Seropositive Rheumatoid Arthritis on Immunosuppressive Therapy

    Karthik Kovuru1, Sylwia Waz1 and Aarti Malik2, 1University of Chicago (Northshore) Internal Medicine Residency, Chicago, IL, 2Department of Rheumatology, University of Chicago/Northshore University, Chicago, IL

    Background/Purpose: Patients with immune-mediated inflammatory diseases on immunosuppressive medications are presumed to be at increased risk for hospital admissions and deaths related to COVID-19 infections.…
  • Abstract Number: 1450 • ACR Convergence 2023

    Clinical Manifestations and Outcomes in Systemic Lupus Erythematosus Patients Who Received Antiviral Therapy During the COVID-19 Omicron Variant Wave: Results from a Single Center Cohort of Puerto Rico

    Lilliana Serrano-Arroyo1, Rafael Ríos-Rivera2, Ariana González-Meléndez2 and Luis M. Vilá2, 1Centro Medico Episcopal San Lucas, San Juan, PR, 2University of Puerto Rico Medical Sciences Campus, San Juan, PR

    Background/Purpose: The impact of COVID-19 in patients with systemic lupus erythematosus (SLE) has been a subject of great concern. Antiviral therapy has emerged as a…
  • Abstract Number: 1815 • ACR Convergence 2023

    The Association of Body Mass Index with SARS-CoV-2 Infection (COVID-19) in Patients with Inflammatory Arthritis on Biologic Disease Modifying Anti-Rheumatic Drugs: Results from the Singapore National Biologics Register

    Preeti Dhanasekaran1, Margaret Ma2, Manjari Lahiri2, Li Wearn Koh3, Stanley Angkodjojo4, Andrew Yu Keat Khor5, James Jiaqi Liu6, Stephanie Wong7 and Siaw Ing Yeo6, 1National University of Singapore, Singapore, Singapore, 2National University Hospital, Singapore, Singapore, 3Tan Tock Seng Hospital, Braddell Heights, Singapore, 4Sengkang General Hospital / Singhealth, Singapore, Singapore, 5Changi General Hospital, Singapore, Singapore, 6Singapore General Hospital, Singapore, Singapore, 7Tan Tock Seng Hospital, Singapore, Singapore

    Background/Purpose: To determine the association of body mass index (BMI) with incident COVID-19 infection in patients with inflammatory arthritis (IA) using biologic disease-modifying anti-rheumatic drugs…
  • Abstract Number: 2159 • ACR Convergence 2023

    Results of a 24-week Open-label, Non-interventional Study of the Efficacy and Safety of Olokizumab Therapy in Patients with Rheumatoid Arthritis After Switching from Anti-B-cell Therapy During the SARS-COV-2 Pandemic

    Sofia Kuzkina1, Eugen Feist2, Nadezhda E. Banshchikova3, Anna A. Akimova3, Alexey E. Sizikov4, Arsen A. Mullagaliev3, Nadezhda A. Ilina4, Elena A. Letyagina3 and Maxim A. Korolev3, 1R-Pharm, Moscow, Russia, 2Helios Department of Rheumatology and Clinical Immunology, Vogelsang-Gommern, Germany, 3Research Institute of Clinical and Experimental Lymphology – branch of Federal State Budget Scientific Institution « Federal Research Center “Institute of cytology and genetics of Siberian Branch of Russian Academy of Sciences", Novosibirsk, Russia, 4Federal State Budgetary Scientific Institution Research Institute of Fundamental and Clinical Immunology, Novosibirsk, Russia

    Background/Purpose: The COVID-19 pandemic has significantly changed the understanding of the safety profile of therapies for immunoinflammatory rheumatic diseases. This is primarily due to the…
  • Abstract Number: 0216 • ACR Convergence 2023

    High Immunogenicity of mRNA Covid-19 Vaccine Booster in Immune Mediated Inflammatory Disease

    Rebecca Haberman1, Rebecca Blank2, Paula Rackoff2, Gary Solomon3, Samrachana Adhikari1, Natalie Azar4, Ramin Herati1, Pamela Rosenthal5, Peter Izmirly6, Jonathan Samuels7, Brian Golden8, Soumya Reddy5, Mark Mulligan1 and Jose Scher6, 1NYU Grossman School of Medicine, New York, NY, 2New York University, New York, NY, 3NYU Langone School of Medicine, Hartsdale, NY, 4NYU Langone, New York, NY, 5NYU School of Medicine, New York, NY, 6New York University School of Medicine, New York, NY, 7NYU Langone, Rye Brook, NY, 8NYU Langone Medical Center - NYU Hospital for Joint Diseases, New York, NY

    Background/Purpose: Patients with immune-mediated inflammatory disorders (IMIDs) have an inherently heightened susceptibility to infection and may be considered high risk for COVID-19, yet IMID populations…
  • Abstract Number: 0446 • ACR Convergence 2023

    Review of Rheumatoid Arthritis Treatment Landscape During the COVID-19 Pandemic

    Rachel Connolly1, MamTing Thoo2, Elizabeth Baynton3 and Denise Baldock3, 1Ipsos, New York, NY, 2Ipsos SDN BHD, Kuala Lumpur, Malaysia, 3Ipsos MORI UK, London, United Kingdom

    Background/Purpose: During the COVID-19 pandemic, guidelines were amended with respect to the prescribing of biologic/tsDMARD usage to treat rheumatoid arthritis (RA). In addition, regulatory reviews…
  • Abstract Number: 1470 • ACR Convergence 2023

    SARS-CoV-2 Antibody Formation After COVID-19 Vaccination in SLE Patients Treated with Belimumab: Single-Center Prospective Observational Study

    Eun song Kang1 and Yong-Gil Kim2, 1Korea University Ansan Hospital, Seoul, South Korea, 2Department of Rheumatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) should be more proactive with the administration of the COVID-19 vaccine, as their systemic conditions are prone to…
  • Abstract Number: 1822 • ACR Convergence 2023

    The Food and Drug Administration’s (FDA’s) Safety Surveillance of Baricitinib and Tocilizumab for COVID-19 (Disclaimer: This Abstract Reflects the Views of the Authors and Not Necessarily Those of the US FDA)

    Laura Kangas1, Lisa Wolf2, Maya Beganovic3, Rachna Kapoor4, James Kidd4, Kate McCartan4, Kim Swank4 and Ida-Lina Diak4, 1Food and Drug Administration, Bethesda, MD, 2Food and Drug Administration, Chevy Chase, MD, 3Food and Drug Administration, Chicago, IL, 4Food and Drug Administration, Silver Spring, MD

    Background/Purpose: Baricitinib, a Janus kinase inhibitor, and tocilizumab, an interleukin-6 receptor antagonist, are two products first approved for the treatment of rheumatoid arthritis. Notably, these…
  • Abstract Number: 2268 • ACR Convergence 2023

    Mental Illness and Outcomes of COVID-19 in Patients with Systemic Lupus Erythematosus: A Global Multicenter Cohort Study

    Hsin-Hua Chen, Taichung Veterans General Hospital, Taichung, Taiwan

    Background/Purpose: Poor COVID-19 outcomes in patients with systemic lupus erythematosus (SLE) has been found to be associated with glucocorticoid dose, male sex, older age, mycophenolate,…
  • Abstract Number: 0217 • ACR Convergence 2023

    Safety and Efficacy of Tixagevimab/Cilgavimab (Evusheld) in Autoimmune Inflammatory Rheumatic Disease Patients – a Prospective Multicenter Open-label Study

    Tali Eviatar1, Victoria Furer2, Ilana Kaufman3, David levartovsky2, Ofir Elalouf2, Devy Zisman4, Tal Gazitt5, Amir Haddad4, Muna Elias6, Joy Feld7, Alexandra Balbir-Gurman8, Yolanda Braun Moscovici9, Sara Pel10, sharon Nevo11, Daphna Paran2 and Ori Elkayam2, 1Tel Aviv Sourasky Medical center, Ramat Gan, Israel, 2Tel Aviv Medical Center, Tel Aviv, Israel, 3Tel Aviv Medical Center, Petah-Tikva, Israel, 4Carmel Medical Center, Haifa, Israel, 5Carmel Hospital, Haifa, Israel, 6rheumatology unit, Haifa, Israel, 7Carmel and Zvulun Medical Centre, Haifa, Israel, 8Rheumatology Institute, Rambam Health Care Campus and Rappaport Faculty of |Medicine, Technion, Haifa, Israel, 9Rambam Heath Care Campus, Haifa, Israel, 10Tel Aviv Medical Center, Modiin, Israel, 11Tel Aviv Sourasky Medical Center, Givataim, Israel

    Background/Purpose: Autoimmune inflammatory rheumatic disease (AIIRD) patients treated with rituximab (RTX) are at risk for severe COVID19 infection, and a blunted humoral response to SARS-CoV-2…
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