ACR Meeting Abstracts

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Abstracts tagged "COVID-19"

  • Abstract Number: 2511 • ACR Convergence 2023

    Superior SARS-CoV-2 Antibody Response Achieved in Rituximab-treated Patients When Vaccinated Against COVID-19 Before Compared to After Rituximab Initiation – Guidance for Future Vaccination Strategies

    Christian Ammitzbøll1, Marianne Kragh Thomsen2, Lars Erik Bartels1, Marie-Louise From Hermansen1, Mathias Hänel3, Rasmus Klose-Jensen1, Mads Christian Lamm Larsen1, Cecile Bo Hansen4, Morgan Oliver Lauritsen1, Susan Mikkelsen5, Clara Mistegaard1, Morten Aagaard Nielsen1, Esben Naeser1, Janne Bille Mønster Olesen5, Peter Garred4, Christian Erikstrup5, Ellen-Margrethe Hauge6 and Anne Troldborg6, 1Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 2Clinical Microbiology, Aarhus University Hospital, Aarhus, Denmark, 3Rheumatollogy, Aarhus University Hospital, Aarhus, Denmark, 4Clinical Immunology, sect. 7631, Rigshospitalet, Copenhagen, Denmark, 5Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark, 6Aarhus University Hospital, Aarhus, Denmark

    Background/Purpose: Rituximab (RTX) treatment significantly decreases the antibody response to COVID-19 vaccines, raising concerns about its use. However, unlike during the pandemic, most patients initiating…
  • Abstract Number: 0152 • ACR Convergence 2023

    Long Covid in Persons with Self-Reported Arthritis – Symptoms, Associated Factors and Functional Limitations

    Debbie Ehrmann Feldman1 and Barbara Mazer2, 1Université de Montréal, Montreal, QC, Canada, 2McGill University, Montreal, QC, Canada

    Background/Purpose: Long covid, a condition whereby signs and symptoms post covid-19 infection continue for more than 12 weeks and are not explained by an alternative…
  • Abstract Number: 0223 • ACR Convergence 2023

    Severity and Risk Factors of Hospitalization of Omicron in Patients with Rheumatoid Arthritis

    Yan Wang1, mengyao zhang2, Sitian Zang1, liang luo3, Chun Li1, Jing He1 and zhanguo li2, 1Peking University People’s Hospital, Beijing, China, 2Peking University People's Hospital, Beijing, China, 3Department of Chinese Medicine, the People's Hospital of Yubei District of Chongqing City, Chongqing, China; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, China

    Background/Purpose: There is still lack of data on the prognosis of patients with RA who have been infected with SARS-Cov-2 Omicron variant, a new strain…
  • Abstract Number: 1093 • ACR Convergence 2023

    Development of Adaptive Immunity Against Different SARS-CoV-2 Variants over the Course of Three COVID-19 Vaccinations in Patients with Inflammatory Rheumatic Diseases

    Liam Huppke1, Paul Wratil2, Marie Bischof2, Stefan Wolfrum1, Fabian Ullrich1, Delila Singh1, Julia Lichtnekert1, Lea Grümme1, Christina Gebhardt1, Klaus Krüger3, Franziska Wiesent4, Alla Skapenko1, Oliver Keppler5 and Hendrik Schulze-Koops6, 1Division of Rheumatology and Clinical Immunology, Department of Internal Medicine IV, University of Munich, Munich, Germany, 2Max von Pettenkofer Institute & Gene Centre, Virology, National Reference Centre for Retroviruses, LMU Munich, Munich, Germany, 3Praxiszentrum St. Bonifatius, Munich, Germany, 4Endokrinologikum München, Munich, Germany, 5Max von Pettenkofer Institute & Gene Centre, Virology, National Reference Centre for Retroviruses, LMU München, Munich, Germany, 6Division of Rheumatology and Clinical Immunology, Department of Internal Medicine IV, Ludwig-Maximilians–University Munich, Munich, Germany

    Background/Purpose: Even though individuals with inflammatory rheumatic diseases (IRDs) were excluded from the SARS-CoV-2 vaccine trails, studies have shown that these individuals at risk of…
  • Abstract Number: 1677 • ACR Convergence 2023

    Two-week Break in Methotrexate Treatment and COVID-19 Vaccine Response. Results of the Vaccine Response on off Methotrexate (VROOM) Study, an Open Label, Prospective, Two-arm Parallel-group, Multi-center, Superiority, Randomized Controlled Trial

    Abhishek Abhishek1, Nicholas Peckham2, Corinna Pade3, Joseph Gibbons3, Lucy Cureton2, Anne Francis2, Vicki Barber2, Jennifer Williams2, duncan Appelbe2, lucy Eldridge2, patrick Julier2, daniel Altmann4, James Bluett5, Tim Brooks6, Laura Coates2, ines Rombach7, Amanda Semper6, Ashley Otter6, Ana Valdes1, Jonathan Nguyen-Van-Tam1, Hywel Williams1, Aine McKnight3, Rosemary Boyton4 and jonathan Cook2, 1University of Nottingham, Nottingham, United Kingdom, 2University of Oxford, Oxford, United Kingdom, 3Queen Mary University of London, London, United Kingdom, 4Imperial College London, London, United Kingdom, 5University of Manchester, Manchester, United Kingdom, 6UK Health Security Agency, Porton Down, United Kingdom, 7University of Sheffield, Sheffield, United Kingdom

    Background/Purpose: Immunosuppressive treatments inhibit vaccine-induced immunity. We evaluated if a two-week interruption of methotrexate treatment immediately after COVID-19 booster improved antibody response against spike protein…
  • Abstract Number: 1935 • ACR Convergence 2023

    Pre-exposure Prophylaxis with Tixegvimab/cilgavimab Is Effective in Limiting the Risk and Severity of COVID-19 in Patients with Auto Immune or Inflammatory Diseases at Increased Risk of Severe COVID-19

    Marion THOMAS1, Maeva MASSON2, Raphaele Seror3, Samuel Bitoun4, Henry DUPUY5, Lazato ESTIBALIZ5, Christophe Richez6, Yannick ALLANORE7 and Jerome AVOUAC8, 1HOPITAL COCHIN AP-HP, Service de Rhumatologie, Paris, France, 2CHU Toulouse, Toulouse, France, 3University Hospital Paris Saclay, Le Kremlin-Bicêtre, France, 4CHU Bicêtre APHP, Le Kremlin-Bicêtre, France, 5CHU Bordeaux, Bordeaux, France, 6Université de Bordeaux, Bordeaux, France, 7Université Paris Cité, Paris, France, 8Rheumatology A Department, Hôpital Cochin, AP-HP Centre - Université Paris Cité, Paris, France

    Background/Purpose: Patients with autoimmune or inflammatory diseases treated with immunosuppressants such as anti-CD20 are at increased risk for severe COVID-19 and have a high probability…
  • Abstract Number: 2536 • ACR Convergence 2023

    DMARD Adherence During the COVID-19 Pandemic and Association with Risk of COVID-19 Infection

    Tanya Selvam, Kelli Peterman, Arezoo Haghshenas and Lucy Liu, Kaiser Permanente Northern California, Oakland, CA

    Background/Purpose: The COVID-19 pandemic affected medication adherence in patients with autoimmune disease (AD) due to their fear of contracting COVID-19, financial hardship, and medication shortage.…
  • Abstract Number: 0202 • ACR Convergence 2023

    Analysis of the Effects of Immunosuppressive Therapy on Herpes Zoster Events After Each of Three Doses of the BNT162b2 mRNA Vaccine in Patients with Spondyloarthritis (SpA)

    Tal Gazitt1, Noa Hayat2, Amir Haddad2, Joy Feld3, Nili Stein2, Idit Lavi2, Ilan Feldhamer4, Arnon Dov Cohen5, Walid Saliba2 and Devy Zisman2, 1Carmel Hospital, Haifa, Israel, 2Carmel Medical Center, Haifa, Israel, 3Carmel and Zvulun Medical Centre, Haifa, Israel, 4Chief Physician's Office, Clalit Health Services, Tel Aviv, Israel, 5Ben-Gurion University of the Negev, Beer-Sheva, Israel

    Background/Purpose: The importance and efficacy of mRNA COVID-19 vaccination in coping with the pandemic are well established, but inconsistencies remain in the data regarding side…
  • Abstract Number: 0224 • ACR Convergence 2023

    Risk Factors and Outcomes for Repeat COVID-19 Infection Among Patients with Systemic Autoimmune Rheumatic Diseases: A Case-control Study

    Emily Kowalski1, Xiaosong Wang1, Naomi Patel2, Yumeko Kawano1, Claire Cook2, Kathleen Vanni1, Grace Qian1, Katarina Bade3, Shruthi Srivatsan2, Zachary Williams2, Zachary Wallace4 and Jeffrey Sparks5, 1Brigham and Women's Hospital, Boston, MA, 2Massachusetts General Hospital, Boston, MA, 3Brigham and Women's Hospital, Boston, MA, 4Massachusetts General Hospital, Newton, MA, 5Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: As initial COVID-19 infections become nearly ubiquitous and the available prevention and treatment strategies evolve, patients with systemic autoimmune rheumatic diseases (SARDs) may be…
  • Abstract Number: 1141 • ACR Convergence 2023

    COVID-19 Vaccination Status and Adverse Events Following SARS-CoV-2 Vaccine in Autoimmune Inflammatory Rheumatic Disease (AIRD) Patients: A Single Center Experience

    Vincent Luceño1, Peter Paolo Daleon1 and Sandra Navarra2, 1University of Santo Tomas Hospital, City of Manila, Philippines, 2University of Santo Tomas Hospital, Joint and Bone Center, Manila, Philippines

    Background/Purpose: Autoimmune inflammatory rheumatic diseases (AIRD) were associated with an increased risk for COVID-19 infection, worse clinical outcomes, and COVID-19- related deaths. Vaccines carry the…
  • Abstract Number: 1754 • ACR Convergence 2023

    Novel and Unique Rheumatoid Factors Cross-React with Viral Epitopes in COVID-19

    Maya Amjadi1, Maxwell Parker2, Zihao Zheng1, Alex Robbins1, Michael Denny1, Sara McCoy3, Irene Ong1 and Miriam Shelef1, 1University of Wisconsin, Madison, WI, 2University of Wisconsin-Madison, Madison, WI, 3University of Wisconsin School of Medicine and Public Health, Middleton, WI

    Background/Purpose: Rheumatoid factors (RFs), polyreactive antibodies canonically known to bind two conformational epitopes of IgG, are a hallmark of rheumatoid arthritis but also can arise…
  • Abstract Number: 2036 • ACR Convergence 2023

    Switch or Stay the Same? Preferences of People with Autoimmune Disease on Rituximab for Different Types of COVID-19 Vaccine Boosters

    Todd Wilson1, Paul R. Fortin2, Ines Colmegna3, Sonia Theriault4, Nathalie Amiable5, Alexandra Godbout5 and Glen Hazlewood1, 1University of Calgary, Calgary, AB, Canada, 2Centre ARThrite - CHU de Québec - Université Laval, Quebec City, QC, Canada, 3The Research Institute of the McGill University Health Centre, Montréal, QC, Canada, 4The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 5Centre ARThrite - CHU de Quebec - Universite Laval, Quebec City, QC, Canada

    Background/Purpose: COVID-19 vaccines are now being offered as regular boosters every 6-12 months for people with autoimmune rheumatic diseases, particularly for people on rituximab, where…
  • Abstract Number: 2564 • ACR Convergence 2023

    The Effectiveness of a Fourth Dose of COVID-19 mRNA Vaccine in Patients with Systemic Autoimmune Rheumatic Diseases Using Immunomodulators: An Emulated Target Trial

    Jennifer Hanberg1, Xiaoqing Fu1, Xiaosong Wang2, Naomi Patel1, Yumeko Kawano2, Abigail Schiff2, Emily Kowalski2, Claire Cook1, Kathleen Vanni2, Krishan Guzzo1, Grace Qian2, Katarina Bade3, Alene Saavedra2, Rathnam Venkat2, Shruthi Srivatsan1, Yuqing Zhang4, Jeffrey Sparks5 and Zachary Wallace6, 1Massachusetts General Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA, 3Brigham and Women's Hospital, Boston, MA, 4Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, 5Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, 6Massachusetts General Hospital, Newton, MA

    Background/Purpose: Many patients with systemic autoimmune rheumatic diseases (SARDs) using immunomodulators have blunted humoral responses to COVID-19 vaccines. As such, the initial mRNA vaccine series…
  • Abstract Number: 0209 • ACR Convergence 2023

    Safety of Bivalent SARS-CoV-2 Vaccines as a Second Booster Dose in Arthritis Patients on Immunosuppressive Therapies

    Hilde Ørbo1, Ingrid Jyssum1, Anne Therese Tveter1, Ingrid Christensen1, Joseph Sexton1, Kristin Hammersbøen Bjørlykke2, Grete B. Kro3, Tore Kvien1, Gunnveig Grødeland4, Ludvig A. Munthe5, Siri Mjaaland6, John Torgils Vaage5, Espen Haavardsholm1, Kristin Kaasen Jørgensen2, Sella Provan7, Silje Watterdal Syversen1 and Guro Goll1, 1Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, 2Department of Gastroenterology, Akershus University Hospital, Oslo, Norway, 3Department of Microbiology, Oslo University Hospital, Oslo, Norway, 4Department of Immunology, Oslo University Hospital, Oslo, Norway, 5Department of Immunology, Oslo University Hospital, Oslo, Norway, 6Norwegian Institute of Public Health, Oslo, Norway, 7Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose: Safety and efficacy of updated bivalent vaccines, containing both the original vaccine variant of SARS-CoV-2 Spike and either Omicron variants BA.1 or BA.4/5, are…
  • Abstract Number: 0225 • ACR Convergence 2023

    Breakthrough SARS-Cov-2 Infection and Disease Flares in Patients with Rheumatoid Arthritis: Result from COVAD E-Survey Study

    Yi-Ming Chen1, Jun-Pen Chen2, Chi-Wei Tseng2, CARLOS ENRIQUE TORO GUTIERREZ3, Elena Nikiphorou4, Ai Lyn Tan5, Arvind Nune6, Esha Kadam7, Masataka Kuwana8, Jessica Day9, Sreoshy Saha10, Tsvetelina Velikova11, James Lilleker12, CARLO VINICIO CABALLERO13, Parikshit Sen14, Hector Chinoy15, Rohit Aggarwal16, Vikas Agarwal17 and Latika Gupta18, 1Taichung Veterans General Hospital, Taichung, Taiwan, 2Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung City, Taiwan, 3Centro de Estudios de Reumatología y Dermatología SAS, Cali, Colombia, 4King's College London, London, United Kingdom, 5University of Leeds, Leeds, United Kingdom, 6Southport & Ormskirk NHS Foundation Trust, Liverpool, United Kingdom, 7Seth Gordhandhas Sunderdas Medical College and King Edwards Memorial Hospital, Mumbai, India, 8Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 9Walter and Eliza Hall Institute, Melbourne, Australia, 10Mymensingh Medical College, Faridpur, Bangladesh, 11Medical Faculty, Sofia University St. Kliment Ohridski, Sofia, Bulgaria, 12Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; Manchester Centre for Clinical Neurosciences, Salford Royal NHS Foundation Trust, Salford, UK. Orcid ID: 0000-0002-9230-4137., Manchester, United Kingdom, 13REUMACARIBE IPS, Barranquilla, Colombia, 14Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi-110002, India., Dalhi, India, 15The University of Manchester, Sale, United Kingdom, 16University of Pittsburgh, Pittsburgh, PA, 17Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, 18Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom

    Background/Purpose: Existing studies have shown that disease activity of patients with rheumatoid arthritis (RA) may surge after COVID-19 infection. However, factors associated with disease flares…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 6:00 PM CT on March 18. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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