Abstracts tagged "Connective tissue diseases"

Abstract Number: 1812 • 2013 ACR/ARHP Annual Meeting
Adverse Events In Connective Tissue Disease-Associated Pulmonary Arterial Hypertension Compared To Idiopathic Pulmonary Arterial Hypertension
Rennie L. Rhee¹, Nicole B. Gabler², Amy Praestgaard², Peter A Merkel³ and Steven M. Kawut⁴, ¹Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ³Division of Rheumatology, University of Pennsylvania and VA Medical Center, Philadelphia, PA, ⁴Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Whether the risk of treatment-related adverse events (AEs) in patients with pulmonary arterial hypertension (PAH) differs based on diagnosis, either connective tissue disease (CTD-PAH)…
Abstract Number: 698 • 2013 ACR/ARHP Annual Meeting
Adverse Events With The Use Of Radiotherapy In Patients With Connective Tissue Diseases and Cancer: A Systematic Review and Meta-Analysis
Maria A. Lopez-Olivo¹, Juan A Martínez-López², Jean H. Tayar³, Mahesh Bavineni⁴ and Maria E. Suarez-Almazor⁵, ¹General Internal Medicine, University of Texas. M.D Anderson Cancer Center, Houston, TX, ²Rheumatology, Section for Autoimmune Diseases, Jiménez Díaz Foundation University Hospital, Madrid, Spain, ³General Internal Medicine, University of Texs, MD Anderson Cancer Center, Houston, TX, ⁴Internal Medicine, Louisiana State University Lafayette, Lafayette, LA, ⁵The Department of General Internal Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX
Background/Purpose: In the era of modern medicine, radiotherapy remains a cornerstone for the multi-modality cancer treatment. Methods: We conducted a comprehensive search for any study…
Abstract Number: 619 • 2013 ACR/ARHP Annual Meeting
Survival and Prognostic Factors In Patients With Connective Tissue Disease Associated Pulmonary Arterial Hypertension: Results From Korean Nationwide Registry
Kwi Young Kang¹, Chan Hong Jeon², Sung Jae Choi³, Seung-Ki Kwok⁴, Seong-Kyu Kim⁵, Hyoun-Ah Kim⁶, Eon Jeong Nam⁷, Yong-Beom Park⁸, Kichul Shin⁹, Jaejoon Lee¹⁰, Chang-Hoon Lee¹¹, Chan-Bum Choi¹², Shin-Seok Lee¹³ and Dae-Hyun Yoo¹⁴, ¹Rheumatology, Internal Medicine, Catholic University of Korea, Incheon St. Mary's Hospital, Seoul, South Korea, ²Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, South Korea, ³Rheumatology, Korea University Medical Center, Seoul, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, South Korea, ⁵Catholic University of Daegu School of Medicine, Daegu, South Korea, ⁶Department of Rheumatology, Ajou University School of Medicine, Suwon, South Korea, ⁷Internal Medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea, ⁸Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea, ⁹Rheumatology, College of Medicine, Seoul National University, Seoul, South Korea, ¹⁰Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ¹¹Department of Internal Medicine, School of Medicine, Wonkwang University, Iksan, Chonbuk, South Korea, ¹²Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, ¹³Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ¹⁴Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Background/Purpose: Pulmonary arterial hypertension (PAH) is a major cause of mortality in connective tissue disease (CTD). We sought to quantify survival and determine factors predictive…
Abstract Number: 1955 • 2012 ACR/ARHP Annual Meeting
Is the Pattern of Capillary Deposition of Complement Membrane Attack COPMLEX Useful in the Differential Diagnosis of Inflammatory?
Patrick Gordon¹, Nuria Villagra², Istvan Bodi², Andrew King², Stefan Buk², Tibor Hortobagyi² and Safa Al-Sarraj², ¹Department of Rheumatology, King's College London, London, United Kingdom, ²Department of Clinical Neuropathology, King's College Hospital, London, United Kingdom
Background/Purpose: Inflammatory myopathies are a heterogeneous group of diseases. We investigated if the location and pattern of deposition of complement membrane attack complex (MAC) can…
Abstract Number: 1824 • 2012 ACR/ARHP Annual Meeting
Do Statins Reduce the Incidence of Connective Tissue Disease? A Retrospective Cohort Study
Thomas W. Schmidt¹, Daniel F. Battafarano¹, Christopher R. Frei², Eric M. Mortensen³ and Ishak Mansi⁴, ¹Rheumatology, San Antonio Military Medical Center, San Antonio, TX, ²Pharmacotherapy Education and Research Center, University of Texas Health Science Center at San Antonio, San Antonio, TX, ³Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, ⁴Internal Medicine, San Antonio Military Medical Center, San Antonio, TX
Background/Purpose: Due to their anti-inflammatory effects, statins were proposed to lower the incidence of connective tissue diseases (CTD). The objective of this study is to…
Abstract Number: 1713 • 2012 ACR/ARHP Annual Meeting
Developing an Index for Disease Activity and Therapeutic Response in Connective Tissue Disease Related Interstitial Lung Disease: Results From A Delphi Exercise: Delivering A Consensus On Domains
Lesley Ann Saketkoo¹, Dörte Huscher², Dinesh Khanna³, Paul F. Dellaripa⁴, Kevin Flaherty⁵, Chester V. Oddis⁶, Kristine Phillips⁷, Athol U. Wells⁸, Christopher P. Denton⁹, Oliver Distler¹⁰, Otylia M. Kowal-Bielecka¹¹, Romy Christmann¹², Nora Sandorfi¹³, David Pittrow¹⁴, Vibeke Strand¹⁵, James R. Seibold¹⁶, Kevin K. Brown¹⁷ and Eric L. Matteson¹⁸, ¹LSU Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, ²German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany, ³Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, ⁴Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁵Department of Critical Care and Pulmonary Medicine, University of Michigan, Ann Arbor, MI, ⁶Rheum/Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ⁷Rheumatology, University of Michigan, Ann Arbor, MI, ⁸Royal Brompton and Harefield NHS Foundation Trust, Department of Radiology, London, United Kingdom, ⁹Centre for Rheumatology and Connective Tissue Diseases, UCL Medical School, London, United Kingdom, ¹⁰Department of Rheumatology and Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, ¹¹Department of Rheumatology and Internal Medicine, Medical University in Bialystok, Bialystok, Poland, ¹²Rheumatology, Boston University School of Medicine, Boston, MA, ¹³Division of Rheumatology, Thomas Jefferson Univ Med Coll, Philadelphia, PA, ¹⁴Institute of Clinical Pharmacology - University of Dresden, Dresden, Germany, ¹⁵Adjunct, Division of Immunology / Rheumatology, Stanford University, Portola Valley, CA, ¹⁶Scleroderma Research Consultants LLC, Avon, CT, ¹⁷Autoimmune Lung Center, National Jewish Hospital, Denver, CO, ¹⁸Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose: Lack of reliable and valid measures of disease activity and clinical response in patients with connective tissue disease (CTD)-related interstitial lung disease (ILD) makes…
Abstract Number: 1649 • 2012 ACR/ARHP Annual Meeting
French Cohort Study of 141 Cases of Autoimmune Congenital Heart Block
Kateri Levesque¹, Alice Maltret², Mohamed Hamidou³, Moez Jallouli⁴, Jean Loup Pennaforte⁵, Pauline Orquevaux⁵, Jean-Charles Piette⁶, Zahir Amoura⁴, Francois Barriere⁷, Jérome Le Bidois², Laurent Fermont², Laurence Cohen⁸, Olivier Meyer⁹, Olivier Fain¹⁰, Arnaud Theulin¹¹, Hugues Lucron¹², Francois Sassolas¹³, Holly Bezanahary¹⁴, Gaëlle Guettrot-Imbert¹⁵, Pascal Seve¹⁶, Elizabeth Diot¹⁷, Nathalie Morel¹, Christophe Deligny¹⁸, Elisabeth Villain² and Nathalie Costedoat-Chalumeau¹⁹, ¹Internal Medicine, Groupe Hospitalier Pitié-Salpétrière, Paris, France, ²Cardiology, Groupe Hospitalier Necker - Enfants Malades, Paris, France, ³Internal Medicine Department, Nantes University Hospital, Nantes, France, ⁴Department of Internal Medicine 2. Referal center for SLE/APS, CHU Pitié-Salpêtrière, Paris, France, ⁵Hu Robert Debre, CHU Reims, Reims, France, ⁶Hospital Pitie, Paris, ⁷Pediatry, CHU Nantes, Nantes, France, ⁸Cardiology, Institut Jacques Cartier, ⁹Rheumatology, Hopital Bichat, Paris, France, ¹⁰Internal Medicine, Service de médecine interne, Université Paris 13, AP-HP, Hôpital Jean Verdier, Bondy, France, ¹¹Rheumatology, Strasbourg University Hospital, Strasbourg, France, ¹²Cardiology, CHU Fort-de-France, Fort de France, Martinique, ¹³Cardiology, CHU Lyon, Lyon, France, ¹⁴Internal Medicine, University Hospital of Limoges, Limoges, France, ¹⁵Internal Medicine, Hopital Gabriel Montpied, Clermont-Ferrand, France, ¹⁶Internal medicine, CHU Lyon, Lyon, France, ¹⁷Department of Internal Medicine, Hôpital Bretonneau, Centre Hospitalier Régional Universitaire de Tours, Tours, France, Tours, France, ¹⁸Rhumatologie Et Médecine Interne, Centre hospitalier Universitaire de Fort de France, Fort de France, Martinique, ¹⁹Internal Medicine, Assistance Publique-Hôpitaux de Paris, Hopital Pitié-Salpétrière, Paris, France
Background/Purpose: Cardiac neonatal lupus manifestations mainly include congenital heart block (CHB), endocardial fibroelastosis and dilated cardiomyopathy. We report the preliminary results of the French registry…
Abstract Number: 1499 • 2012 ACR/ARHP Annual Meeting
The Soluble Guanylate Cyclase Mediates Its Anti-Fibrotic Effects by Inhibiting TGF-β Signaling
Christian Beyer¹, Sonia C. Schindler², Alfiya Distler³, Clara Dees⁴, Helena Reichert², Hümeyra Akan², Peter Sandner⁵, Oliver Distler⁶, Georg Schett⁷ and Joerg HW Distler³, ¹Department of Internal Medicine 3, Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ²Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany, ³Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ⁴Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ⁵Bayer Health Care, Global Drug Discovery – Common Mechanism Research, Bayer Health Care, Global Drug Discovery – Common Mechanism Research, Wuppertal, Germany, ⁶Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁷Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany
Background/Purpose: We have recently demonstrated that stimulation of the soluble guanylate cyclase (sGC) has potent anti-fibrotic activity in different models of fibrosis. sGC stimulation increases…
Abstract Number: 197 • 2012 ACR/ARHP Annual Meeting
Collapsing Glomerulopathy in Collagen Vascular-Like Disease
Rawad Nasr¹, Christine Johns² and Elie Gertner³, ¹Rheumatology - Internal Medicine, University of Minnesota, Minneapolis, MN, ²Section of Nephrology, Regions Hospital, St Paul, MN, ³Section of Rheumatology, Regions Hospital and University of Minnesota Medical School, St. Paul, MN
Background/Purpose: Background: Collapsing Glomerulopathy (CG) is an uncommon podocytopathy with distinct clinical and pathological characteristics. It is usually associated with HIV disease or parvovirus B19…
Abstract Number: 70 • 2012 ACR/ARHP Annual Meeting
The Impact of Systemic Autoimmune Rheumatic Disease On One-Year Mortality in Congestive Heart Failure Patients: A Population-Level Analysis
Stephanie O. Keeling¹, Asvina Bissonauth¹, Becky Leung² and Padmaja Kaul², ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Cardiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Little is known about the prevalence of systemic autoimmune rheumatic diseases (SARDs) in patients with congestive heart failure (CHF) and its contribution to long-term…

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