Abstracts tagged "Computed tomography (CT)"

Abstract Number: 0674 • ACR Convergence 2025
Quantitative Imaging in Systemic Sclerosis Patients Receiving Sodium Thiosulfate for Calcinosis Cutis
Ian Odell¹, Crystal Cheung¹, Megan Wu², Stephanie Perez³, Agrani Dixit⁴, Cassandra van Horn³, Muhammad Hamdan⁵, Baran Gunes⁶, Sophia Kujawski⁷, Hyojeong Lee³, Annie Wang³, Denise Esserman⁸, Michael Zamani⁹, F. Perry Wilson³, John Onofrey³, Xenophon Papademetris³ and Monique Hinchcliff¹⁰, ¹Yale University School of Medicine, New Haven, CT, ²Yale University School of Medicine, Greenville, ³Yale University School of Medicine, New Haven, ⁴Yale School of Medicine, New Haven, CT, ⁵Yale University School of Medicine, Mansfield, ⁶Yale University School of Medicine, Pompton Plains, NJ, ⁷The George Washington University, New Haven, CT, ⁸Yale University School of Public Health, New Haven, ⁹Independent Statistician, Washington D.C., ¹⁰Yale School of Medicine, Westport, CT
Background/Purpose: Calcinosis cutis (CC) is a disabling skin condition associated with systemic sclerosis (SSc). Although many CC treatments including sodium thiosulfate (STS) have been proposed,…
Abstract Number: 0540 • ACR Convergence 2025
Low-Dose CT reveals syndesmophyte progression in axial SpA, particularly in the thoracic spine: Insights from the SPACE cohort covering early and established disease
Manouk de Hooge¹, Mary Lucy Marques², Gizem Ayan³, Miranda van Lunteren⁴, Liese de Bruin⁴, Monique Reijnierse⁵, Désirée Van Der Heijde⁴, Sofia Ramiro⁶ and Floris A. van Gaalen⁴, ¹Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ²Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; and Coimbra Local Health Unit, Coimbra, Portugal, ³Ankara Research and Training Hospital, Ankara, Turkey, ⁴Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁶Leiden University Medical Center, Bunde, Netherlands
Background/Purpose: Low-dose computed tomography (ldCT) has not previously been used to assess pt with axial spondyloarthritis (axSpA) early in their disease course, especially those with…
Abstract Number: 2566 • ACR Convergence 2025
Using Abdominal CT-Derived Bone Mineral Density and Psoas Volume for Opportunistic Osteoporosis Screening and Fracture Risk Assessment
Ye Liu¹, Hongke Wu¹, Amy Mudano², Omar Safarini¹, John Eddins¹, Carlos Cardenas¹, Lesley Jackson¹, Jeffrey Curtis³ and Steven Rothenberg¹, ¹University of Alabama at Birmingham, Birmingham, AL, ²Foundation for Advancing Science, Technology, Education and Research (FASTER), Hoover, AL, ³Foundation for Advancing Science, Technology, Education and Research, Birmingham, AL
Background/Purpose: Osteoporosis (OP) is assessed by dual-energy X-ray absorptiometry (DXA) for bone mineral density (BMD). Computed tomography (CT) offers an alternative for “opportunistic” screening. This…
Abstract Number: 2531 • ACR Convergence 2025
Coronary periarteritis in IgG4-Related Disease
Georges El Hasbani¹, Daniel Larson², Matthew Koster¹ and Kenneth Warrington¹, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Rochester
Background/Purpose: IgG4-related disease (IgG4-RD) is characterized by chronic inflammation and fibrosis, which can affect multiple organs, especially the pancreas, salivary glands, and retroperitoneum (1). It…
Abstract Number: 2306 • ACR Convergence 2025
Prevalence and Clinical Significance of the Gastrointestinal Fat Halo Sign in Patients with Psoriatic Arthritis: A Cross-Sectional Study
Amir Haddad¹, Kathrien Mousa¹, Kateryna Milman¹, Najwan Nassrallah¹, Devy Zisman² and Sharbell Hashoul³, ¹Carmel Medical Centre, Haifa, Israel, ²Carmel Medical Center, Haifa, Israel, ³The Faculty of Humanities and Social Sciences. Uno Academic College, Haifa, Israel
Background/Purpose: The existence of a gut-joint axis is widely described in spondyloarthritis, linking intestinal dysbiosis, subclinical gut inflammation, and arthritis. The fat halo sign is…
Abstract Number: 2017 • ACR Convergence 2025
Baseline and 2-year Follow-up of Pulmonary Function Among CTD-ILD Subtypes
Ivana Ilic, Anchal Sabharwal, Galina Marder and Sonali Narain, Northwell, Great Neck
Background/Purpose: Interstitial lung disease is a major cause of morbidity and mortality in patients with connective tissue disease (CTD-ILD). Evaluation of ILD severity and progression…
Abstract Number: 2009 • ACR Convergence 2025
Value of New PREVENT Calculator in Detecting Cardiovascular Disease in Patients with Gout
Patrick Williamson¹, Rouhin Sen² and Angelo Gaffo³, ¹Tinsley Harrison Internal Medicine Residency, Department of Medicine, University of Alabama at Birmingham, Birmingham, ²University of Alabama at Birmingham, Department of Medicine, Division of Clinical Immunology & Rheumatology, Birmingham, ³Division of Rheumatology and Clinical Immunology, University of Alabama, Birmingham, AL, USA; Birmingham VA Medical Center, Birmingham, AL, USA, Birmingham, AL
Background/Purpose: Gout is associated with a 50% increased risk of cardiovascular disease (CVD).1 The current recommendation for evaluating CVD risk in gout is to use…
Abstract Number: 1950 • ACR Convergence 2025
Pericoronary fat enhancement in rheumatoid arthritis differs from controls and associates with coronary atherosclerosis independently of epicardial fat volume
Frederik Enevoldsen¹, Sarah Ormseth², Dzenan Masic¹, Matthew Budoff³, Ellen-Margrethe Hauge¹ and George Karpouzas³, ¹Aarhus University, Aarhus, Denmark, ²The Lundquist Institute for Biomedical Innovation, Torrance, CA, ³Harbor-UCLA Medical Center, Torrance, CA
Background/Purpose: Pericoronary adipose tissue attenuation (PCATa) reflects the composition of the fat directly surrounding the coronary arteries and is associated with coronary wall inflammation. In…
Abstract Number: 1947 • ACR Convergence 2025
Coronary computed tomography incidental findings in rheumatoid arthritis.
Emmanuel Tapia López¹, Jessica Roldan Ortega², Evelyn Aranda Cano³, Itzel Palafox Sosa⁴, Luz Viruel⁵, Luis H Silveira⁶, Laura Aline Martinez-Martinez⁷ and Francisco Castillo-Castellon⁸, ¹Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico, Naucalpan de Juarez, Estado de México, Mexico, ²INSTITUTO NACIONAL DE CARDIOLOGIA, Ciudad de México, Federal District, Mexico, ³Departament of rheumatology Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de Mexico, Federal District, Mexico, ⁴Escuela Superior de Medicina-Instituto Politècnico Nacional, ciudad de mexico, Federal District, Mexico, ⁵Universidad Autónoma del Estado de Hidalgo, Tula de Allende, Hidalgo, Mexico, ⁶Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico, Mexico City, Mexico, ⁷Rheumatology Department at National Institute of Cardiology Ignacio Chávez, Mexico City, Federal District, Mexico, ⁸Instituto Nacional de Cardiología Ignacio Chavez, Mexico
Background/Purpose: Patients with rheumatoid arthritis (RA) have a greater cardiovascular risk than does the general population. The coronary calcium score is a measure used to…
Abstract Number: 1751 • ACR Convergence 2025
Disease activity, inflammation, and older age are associated with quantitative interstitial abnormalities in early RA: Results from a multicenter, prospective cohort study
Gregory McDermott¹, Xiaosong Wang², Misti Paudel³, Ying Qi⁴, Emily Kowalski⁵, Grace Qian⁶, Liya Sisay Getachew⁵, Kevin Mueller⁶, Alene Saavedra⁶, Lauren O'Keeffe⁶, Natalie Davis¹, Alison Puri⁷, Kathleen Vanni⁶, Caleb Bolden⁸, Tina Mahajan⁹, Erica Mulcaire-Jones¹⁰, Neda Kortam¹¹, Pierre Antoine Juge¹², Tracy J. Doyle¹³, Marcy Bolster¹⁴, Kevin Deane¹⁵, Dinesh Khanna¹⁰, Bryant England⁹, Raul San Jose Estepar⁶, George Washko⁶ and Jeffrey Sparks⁵, ¹Brigham and Women's Hospital, Brookline, MA, ²Brigham and Women's Hospital, Natick, MA, ³Brigham and Women's Hospital, Division of Rheumatology, Inflammation, and Immunity, Boston, MA, ⁴Brigham and Women’s Hospital, Boston, ⁵Brigham and Women's Hospital, Boston, MA, ⁶Brigham and Women's Hospital, Boston, ⁷Boston University, Brookline, MA, ⁸Massachusetts General Hospital, Boston, ⁹University of Nebraska Medical Center, Omaha, NE, ¹⁰University of Michigan, Ann Arbor, MI, ¹¹University of Michigan, Ann Arbor, ¹²Hopital Bichat, APHP, Paris, France, ¹³Brigham and Women's Hospital, West Roxbury, MA, ¹⁴Massachusetts General Hospital, Concord, MA, ¹⁵University of Colorado Denver Anschutz Medical Campus, Aurora, CO
Background/Purpose: Quantitative computed tomography (QCT) methods using machine learning have been developed to automatically quantify parenchymal lung features on chest CT imaging. QCT can detect…
Abstract Number: 1576 • ACR Convergence 2025
Impact of COVID-19 Infection on Fibrosis Progression in CTD-Associated ILD: An AI-Based Quantitative CT Study
kyung-Ann Lee¹, Hyun-Sook Kim² and Boda Nam³, ¹Soonchunhyang University Hospital Seoul: Soonchunhyang University Hospital, Seoul, Republic of Korea, ²Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea, ³Chung-Ang University Hospital, Seoul, Republic of Korea
Background/Purpose: Pulmonary fibrosis is a recognized sequela of severe COVID-19 pneumonia, but its additive impact on pre-existing interstitial lung disease (ILD)—particularly in patients with connective…
Abstract Number: 1567 • ACR Convergence 2025
Deep-learning analysis of HRCT images predicts progression and mortality in systemic sclerosis-related interstitial lung disease
Enrico De Lorenzis¹, Rosa D'Abronzo², Pier Giacomo Cerasuolo³, Lucio Calandriello⁴, Gabriella Alonzi³, Giuseppe Cicchetti², gerlando Natalello³, Bruno Iovene⁵, Lucia Lanzo³, Francesco Varone⁶, Giacomo Sgalla⁷, Luca Richeldi⁸, anna Rita Larici⁴, Maria Antonietta D'Agostino³ and Silvia Laura Bosello⁹, ¹Catholic University of the Sacred Heart, Roma, Rome, Italy, ²Division of Radiology - Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy, ³Division of Rheumatology and Clinical Immunology - Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, ⁴Division of Radiology - Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, ⁵Division of Rheumatology - Catholic University of the Sacred Heart, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Rome, Italy, ⁶Division of Respiratory Medicine - Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, ⁷Catholic University of the Sacred Heart, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Rome, Italy, ⁸Division of Respiratory Medicine - Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy, ⁹Division of Rheumatology and Clinical Immunology - Catholic University of the Sacred Heart, Rome, Italy, Rome, Italy
Background/Purpose: Interstitial lung disease (ILD) is a major complication in systemic sclerosis (SSc) patients, associated with substantial morbidity and mortality. Functional, imaging, and clinical measures…
Abstract Number: 1561 • ACR Convergence 2025
Usefulness of HRCT in screening of interstitial lung disease in patients with systemic sclerosis without risk factors of clinical suspicion
Carlos de la Puente-Bujidos¹, Antia Garcia Fernandez², Verónica García García¹, Jesús Loarce³ and Sandra Garrote-Corral¹, ¹Ramón y Cajal University Hospital, Madrid, Spain, ²Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain, ³Ramón y Cajal University Hospital, Madrid, Spain
Background/Purpose: In 2019 a European expert consensus suggested that all patients with systemic sclerosis (SSc) should be screened with HRCT for interstitial lung disease (ILD)…
Abstract Number: 1556 • ACR Convergence 2025
Latent Profiles of Parenchymal Abnormalities and Vascular Features Measured by Quantitative CT Identifies a Subgroup of Systemic Sclerosis Patients With a Greater Lung Function Decline Over Time
Alicia Hinze¹, Nishanth Katurkuri², Robert Vassallo², Ami Shah³, Ryan Lennon², Brian Bartholmai² and Cynthia Crowson⁴, ¹Mayo Clinic - Rochester, MN, Rochester, MN, ²Mayo Clinic, Rochester, MN, ³Johns Hopkins Rheumatology, Baltimore, MD, ⁴Mayo Clinic, Stewartvillle, MN
Background/Purpose: The clinical course of interstitial lung disease (ILD) in systemic sclerosis (SSc) is highly variable--some patients experience progressive loss of lung function while others…
Abstract Number: 0690 • ACR Convergence 2025
Quantitative 18F-FDG PET-CT of the lungs detects treatment induced changes in patients with early severe diffuse cutaneous systemic sclerosis and interstitial lung disease
Bo Broens¹, esther Nossent¹, Lilian Meijboom¹, Gerben Zwezerijnen¹, julia Spierings², Jeska de Vries-Bouwstra³, Jacob M. van Laar⁴, Conny van der Laken¹ and Alexandre Voskuijl⁵, ¹Amsterdam UMC, Amsterdam, Netherlands, ²Department of Rheumatology & Clinical Immunology, University Medical Center, Ultrecht, The Netherlands, Utrecht, Netherlands, ³Leiden University Medical Center, Leiden, Netherlands, ⁴UMC Utrecht, Utrecht, Netherlands, ⁵Amsterdam University Medical Center, Amsterdam, Netherlands
Background/Purpose: Patients with early severe diffuse cutaneous systemic sclerosis (dcSSc) with interstitial lung disease (ILD) have poor prognosis. New tools are needed to improve treatment…

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