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Abstracts tagged "computational and Drug Repositioning"

  • Abstract Number: 1041 • ACR/ARP Annual Meeting 2019

    Computational Methods for Drug Repositioning of Systemic Sclerosis Using Gene Fold-Change and Network Analyses

    Dillon Popovich1, Michael Whitfield 2, Yue Wang 3, Guoshuai Cai 4 and Mengqi Huang 5, 1Geisel School of Medicine at Dartmouth College, Hanover, 2Geisel School of Medicine at Dartmouth College, Biomedical Data Science at Dartmouth College, Hanover, 3Geisel School of Medicine at Dartmouth, Hanover, NH, 4Arnold school of Public Health, University of South Carolina, Columbia, SC, 5Geisel School of Medicine at Dartmouth College, Hanover, NH

    Background/Purpose: Clinical trials with systemic sclerosis (SSc) patients have yet to lead to an FDA approved treatment.  We have adopted a gene fold-change analysis called…

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