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Abstracts tagged "complement and inflammation"

  • Abstract Number: 2182 • ACR/ARHP Annual Meeting 2014

    Investigating the Roles of Factor H-Related Proteins in Systemic Lupus Erythematosus (SLE) and Other Autoimmune Diseases

    Alexandra Antonioli1, Brandon Renner2, Joshua Thurman3, V. Michael Holers4 and Jonathan Hannan4, 1Department of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 2University of Colorado School of Medicine, Aurora, CO, 3Renal Division, University of Colorado School of Medicine, Aurora, CO, 4Rheumatology Division, University of Colorado School of Medicine, Aurora, CO

    Background/Purpose Complement plays a central role in the pathogenesis of systemic lupus erythematosus (SLE) wherein inappropriate activation of complement leads to substantial tissue damage, especially…

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