ACR Meeting Abstracts

ACR Meeting Abstracts

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Abstracts tagged "comparative effectiveness"

  • Abstract Number: 1526 • ACR Convergence 2023

    Evusheld Efficacy and Safety in Autoimmune Rheumatic Diseases (AIRD) Treated by B Cell Depeting Therapy or Autologous Stem Cell Transplantation: A Prospective Observational Study

    Lisa Kaly1, mark Volevich1, shiri keret2, Abid Awisat3, Aniela Shouval1, Itzhak Rosner4, Michel Rozenbaum1, Nina Boulman1 and Doron Rimar1, 1Bnai Zion Medical Center, Haifa, Israel, 2Bnai Zion, Atlit, Israel, 3Bney-Zion Medical Center, Baqa Elgharbiya, Israel, 4Bnai Zion Medical Center/Technion, Haifa, Israel

    Background/Purpose: B cell depleting therapy (rituximab) and Autologous Hematopoietic Stem Cell transplantation (AHSCT) result in impaired ability to mount a humoral immune response. Evusheld (tixagevimab…
  • Abstract Number: 1551 • ACR Convergence 2023

    Measurement of Sinonasal Disease Activity in Granulomatosis with Polyangiitis

    Roger Yang1, Ellen Romich2, Shubhasree Banerjee3, Naomi Amudala3, Peter Merkel3, Joshua Baker3 and Rennie Rhee3, 1University of Pennsylvania, Montréal, QC, Canada, 2Hospital of the University of Pennsylvania, Media, PA, 3University of Pennsylvania, Philadelphia, PA

    Background/Purpose: In granulomatosis with polyangiitis (GPA), sinonasal inflammation can be severe and significantly impact quality of life. Little is known about the most effective local…
  • Abstract Number: 1579 • ACR Convergence 2023

    Sodium-Glucose Co-transporter-2 Inhibitors and the Risk of Cardiac and Renal Outcomes in Systemic Lupus Erythematosus

    April Jorge1, Baijun Zhou1, Natalie McCormick1, Chio Yokose1, Yuqing Zhang2 and Hyon K. Choi3, 1Massachusetts General Hospital, Boston, MA, 2Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, 3Massachusetts General Hospital and Harvard Medical School, Lexington, MA

    Background/Purpose: Sodium-glucose cotransporter-2 inhibitors (SGLT2) have benefits on kidney and cardiovascular (CV) outcomes that are largely independent of glycemic control. These benefits have been demonstrated…
  • Abstract Number: 1673 • ACR Convergence 2023

    Immunomodulatory Treatment and Autoimmune Patient Responses to COVID-19 Booster Shots: Results from the Covid-19 VaccinE Response in Rheumatology Patients (COVER) Study

    Amy S. Mudano1, Gary Cutter2, Ted R Mikuls3, Geoffrey Thiele4, Emily Holladay2, Kevin Withrop5, Mark Law4, Bart Hamilton4, Monique Bastidas6, Michael Zikry6, Kelly Chun6, Michael George7 and Jeffrey Curtis2, 1Illumination Health, Hoover, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3Division of Rheumatology and Immunology, University of Nebraska Medical Center, Omaha, NE, 4University of Nebraska Medical Center, Omaha, NE, 5Oregon Health & Science University, Schools of Medicine and Public Health,, Portland, OR, 6Labcorp, Calabasas, CA, 7University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Given an increased risk of COVID-19 in patients with autoimmune conditions, we must better understand the immunogenicity and safety of SARS-CoV-2 vaccines in people…
  • Abstract Number: 062 • 2023 Pediatric Rheumatology Symposium

    Assessment of Barriers and Facilitators in Implementation of the Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans

    Cagri Yildirim-Toruner1, Daniel Glaser2, Timothy Beukelman3, Stacy Ardoin4, Ahmar Hashmi5, Rajdeep Pooni6, Maria Fernandez5, Vincent Del Gaizo7, Leslie Hanrahan7, Mary Ellen Riordan8, Stacey Tarvin9 and CARRA Registry Investigators7, 1Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 2Yale University School of Medicine, New Haven, CT, 3University of Alabama at Birmingham, Birmingham, AL, 4Nationwide Children's Hospital, Columbus, OH, 5The University of Texas Health Sciences Center at Houston, Institute for Implementation Science, Houston, TX, 6Stanford University, Palo Alto, CA, 7CARRA, Washington, DC, 8Hackensack Meridian Health/ Joseph M. Sanzari Children's Hospital, Hackensack, NJ, 9Riley Hospital for Children at Indiana University Health, Indianapolis, IN

    Background/Purpose: Since 2010, the Childhood Arthritis and Rheumatology Research Alliance (CARRA) has developed 12 consensus treatment plans (CTP) with the aim of reducing treatment variability…
  • Abstract Number: 1679 • ACR Convergence 2022

    The Childhood Arthritis and Rheumatology Research Alliance Start Time Optimization of Biologic Therapy in Polyarticular JIA (STOP-JIA) Study: Three-Year Outcomes

    Yukiko Kimura1, Sarah Ringold2, George Tomlinson3, Laura Schanberg4, Anne Dennos5, MaryEllen Riordan6, Vincent Del Gaizo7, Katherine Murphy8, Pamela Weiss9, Brian Feldman10, Mei Sing Ong11 and Marc Natter12, 1Hackensack Meridian Health, New York, NY, 2Janssen, Seattle, WA, 3University of Toronto, Toronto, ON, Canada, 4Duke University Medical Center, Durham, NC, 5Duke University, Durham, NC, 6Hackensack Meridian Health, Hackensack, NJ, 7CARRA, Inc, Washington, DC, 8CARRA, Inc, New Orleans, LA, 9Children's Hospital of Philadelphia, Glen Mills, PA, 10Division of Rheumatology, The Hospital for Sick Children; Child Health Evaluative Services, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 11Harvard Pilgrim Institute, Boston, MA, 12Boston Children's Hospital, Boston, MA

    Background/Purpose: The CARRA STOP-JIA study compared the effectiveness of the CARRA Consensus Treatment Plans (CTPs) in achieving clinically inactive disease (CID) in untreated polyarticular JIA…
  • Abstract Number: 1841 • ACR Convergence 2022

    To Combine or Not to Combine: Influence of Immunosuppressive Drug Combination in the Induction of Therapeutic Response in Non-infectious Uveitis

    María Paula Álvarez Hernández1, Alfredo Madrid-García2, Alejandro Gómez Gómez3, Lara Borrego Sanz4, Rosalía Méndez Fernández4, Pedro Arriola Villalobos4, Esperanza Pato Cour5, David Díaz Valle4 and Luis Rodriguez-Rodriguez5, 1Hospital Clínico San Carlos, Madrid, Spain, 2Instituto de Investigación Sanitaria San Carlos, Rheumatology, Madrid, Spain, Madrid, Spain, 3Hospital Infanta Sofia, Rheumatology, San Sebastián de los Reyes, Madrid, Spain, 4Instituto de Investigación Sanitaria San Carlos, Ophthalmology, Madrid, Spain, 5Instituto de Investigación Sanitaria San Carlos, Rheumatology, Madrid, Spain

    Background/Purpose: Non-infectious uveitides (NIUs) include a heterogeneous group of sight-threatening and incapacitating conditions. Their correct management sometimes requires the use of immunosuppressive drugs (ISDs), prescribed…
  • Abstract Number: 0058 • ACR Convergence 2022

    Health System Improvement in Inpatient ANA and Serologic Test Utilization

    Saloni Goyal1, Yasin kanakrieh1, Marie O'Brien1, Amy Slenker1, Kathryn Zaffiri1 and James Ross2, 1Lehigh Valley Health Network, Allentown, PA, 2lvhn, Macungie, PA

    Background/Purpose: In 2005 Lehigh Valley Health Network (LVHN) instituted order sets for ANA serologic reflex testing with the objective to facilitate more efficient patient work-up…
  • Abstract Number: 0133 • ACR Convergence 2022

    Retention Rate of Targeted Therapies in Erdheim-Chester Disease

    Corrado Campochiaro1, alessandro tomelleri1, Francesco Pegoraro2, Giovanni Galardi3, Nicola Farina4, Martina Mazzariol5, Francesco Catamerò6, Giacomo De Luca4, Giulio Cavalli4, Augusto Vaglio7 and Lorenzo Dagna8, 1IRCCS San Raffaele Hospital. Vita-Salute San Raffaele University, Milano, Italy, 2Department of Health Sciences, University of Florence, Firenze, Italy, 3Department of Health Sciences, University of Florence, Florence, Italy, 4IRCCS San Raffaele Hospital - Vita-Salute San Raffaele University, Milano, Italy, 5University of Turin, Torino, Italy, 6Vita-Salute San Raffaele University, Milano, Italy, 7Azienda Ospedaliero Universitaria Meyer, Parna, Italy, 8IRCCS San Raffaele Hospital and Vita-Salute San Raffaele University, Milano, Italy

    Background/Purpose: Erdheim-Chester disease (ECD) is a rare non-Langerhans histiocytosis with a broad clinical spectrum. The therapeutic landscape of ECD has remarkably changed over the last…
  • Abstract Number: 0576 • ACR Convergence 2022

    Comparative Effectiveness of Osteoporosis (OP) Therapies Among a Population of Postmenopausal (PM) Women in the United States (U.S.)

    Min Kim1, Leah J McGrath2, David Pritchard2, Peter Samai2, Jay Lin1, Robert Kees Stad3, Leslie Spangler1, Michele McDermott1, Brian D Bradbury4 and M Alan Brookhart2, 1Amgen, Inc., Thousand Oaks, CA, 2NoviSci, Inc., Durham, NC, 3Amgen Inc., Zug, Switzerland, 4Amgen Inc., 1 Amgen Center Drive

    Background/Purpose: Although clinical trials evaluating the efficacy of osteoporosis (OP) therapies have shown that denosumab (Dmab) significantly increases bone mineral density at pivotal sites compared…
  • Abstract Number: 0714 • ACR Convergence 2022

    Real-World Treatment Effectiveness of Disease-Modifying Anti-Rheumatic Drugs by Serostatus Among Patients with Rheumatoid Arthritis

    Yinzhu Jin, Jun Liu, Rishi Desai and Seoyoung Kim, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Serostatus may be associated with different responses to treatment with biologic disease-modifying anti-rheumatic drugs (DMARD) or Janus kinase inhibitors (JAKi) in patients with rheumatoid…
  • Abstract Number: 0934 • ACR Convergence 2022

    Impact of Tapering Targeted Therapy on Disease Activity Is Different Based on Concomitant Methotrexate Use in Patients with Rheumatoid Arthritis: A Nationwide Cohort Study

    Jun Won Park1, Min Jung Kim2, Hyoun-Ah Kim3, Jinhyun Kim4, Eun Bong Lee1 and Kichul Shin5, 1Seoul National University Hospital, Seoul, Republic of Korea, 2Seoul Metropolitan Government Boramae Medical center, Dongjak-gu, Seoul, Republic of Korea, 3Ajou University School of Medicine, Suwon, Republic of Korea, 4Chungnam National University Hospital, Jung-gu, Daejeon, South Korea, 5Seoul Metropolitan Government- Seoul National University Boramae Medical Center, Seoul, Republic of Korea

    Background/Purpose: The American College of Rheumatology and the European League Against Rheumatism recommend using methotrexate (MTX) with targeted therapy. Previous studies have shown that tapering…
  • Abstract Number: 1084 • ACR Convergence 2022

    Rituximab versus Cyclophosphamide for Induction Therapy in Granulomatosis with Polyangiitis: A Target Trial Emulation Study

    Xavier Puéchal1, Michele Iudici2, Elodie Perrodeau3, bernard bonnotte4, Francois Lifermann5, Thomas Le Gallou6, Alexandre Karras7, Claire Blanchard-Delaunay8, Thomas Quéméneur9, Achille Aouba10, Olivier Aumaître11, Vincent Cottin12, Mohamed Hamidou13, Marc Ruivard11, Pascal Cohen1, Luc Mouthon1, Loïc Guillevin1, Philippe Ravaud3, Raphaël Porcher3 and Benjamin Terrier1, 1National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris, France, 2Division of Rheumatology, Geneva University Hospitals, Geneva, Switzerland, 3Université Paris Cité, Hôtel-Dieu, Paris, France, 4Centre Hospitalo-Universitaire de Dijon, Dijon, France, 5Dax Hospital, Dax, France, 6Rennes Sud University Hospital, Rennes, France, 7HEGP, Paris, France, 8Niort Hospital, Niort, France, 9Valenciennes Hospital, Valenciennes, France, 10Department of Internal Medicine, UR4650 PSIR, Normandie Univ, UNICAEN, CHU de Caen Normandie, Caen, France, 11Clermont Ferrand University Hospital, Clermont-Ferrand, France, 12Coordinating Reference Center for Rare Pulmonary Diseases, Louis Pradel Hospital, University of Lyon, INRAE, Lyon, France, 13Nantes University Hospital, Nantes, France

    Background/Purpose: Randomized controlled trials showed rituximab (RTX)'s non-inferiority to cyclophosphamide (CYC) for induction therapy of ANCA-associated vasculitis and neither treatment was favoured in granulomatosis with…
  • Abstract Number: 1430 • ACR Convergence 2022

    Time to First Remission and Prevalence of Sustained Remission After Etanercept Biosimilar (ETA-B) or Originator (ETA-O) Initiation in Rheumatoid Arthritis

    Cristiano Moura1, Luck Lukusa1, Laura Yan1, Walter P Maksymowych2, Denis Choquette3, Gilles Boire4 and Sasha Bernatsky1, 1Research Institute of the McGill University Health Centre, Montréal, QC, Canada, 2Department of Medicine, University of Alberta, Edmonton, AB, Canada, 3Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada, 4Universite de Sherbrooke, Sherbrooke, QC, Canada

    Background/Purpose: The first biosimilar etanercept (ETA-B) was approved in Canada in 2016, but real-world data comparing the effectiveness of ETA-B versus its equivalent originator (ETA-O)…
  • Abstract Number: 1432 • ACR Convergence 2022

    Pharmacokinetic Evaluation of a Proposed Adalimumab Biosimilar MSB11022 versus the US-Licensed Reference Product: Results of a Randomized, Double-Blind, 3-Arm Parallel-Group, Single-Dose Trial in Healthy Subjects

    Anna Dryja1, Anna Lucia Buccarello2, Isabelle Gaillard2 and Joëlle Monnet2, 1MTZ Clinical Research Sp. z o.o.,, Warsaw, Poland, 2Fresenius Kabi Swiss BioSim, Eysins, Switzerland

    Background/Purpose: Adalimumab, a recombinant fully human monoclonal immunoglobulin G1 antibody, is a biologic directed against tumor necrosis factor-alpha indicated for use in a range of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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