ACR Meeting Abstracts

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Abstracts tagged "comparative effectiveness"

  • Abstract Number: 2022 • ACR Convergence 2024

    Could Initiation of Sodium Glucose Co-Transporter-2 Inhibitors Reduce the Need for Conventional Urate-Lowering Therapy and Flare Medications in Patients with Gout?Population-Based Target Trial Emulation Studies

    Natalie McCormick1, Chio Yokose2, Leo Lu3, Sharan Rai1, Gregory Challener1 and Hyon K. Choi4, 1Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Waltham, MA, 3Arthritis Research Canada, Vancouver, BC, Canada, 4Massachusetts General Hospital, Lexington, MA

    Background/Purpose: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) lower serum urate levels and are associated with reduced risk of incident gout as well as recurrent flares [Annals IM…
  • Abstract Number: 2008 • ACR Convergence 2023

    Comparative Effectiveness of Denosumab versus Alendronate Among Postmenopausal Women with Osteoporosis in the U.S. Medicare Program

    Jeffrey Curtis1, Tarun Arora2, Ye Liu1, Tzu-Chieh Lin3, Leslie Spangler3, Vanessa C. Brunetti3, Robert K. Stad3, Michele McDermott3, Brian D. Bradbury3 and Min Kim3, 1University of Alabama at Birmingham, Birmingham, AL, 2Foundation for Advancing Science, Technology, Education, and Research, Birmingham, AL, 3Amgen, Inc., Thousand Oaks, CA

    Background/Purpose: Although clinical trials have shown that denosumab (Dmab) significantly increases bone mineral density at key skeletal sites more than oral bisphosphonates, evidence is lacking…
  • Abstract Number: 2412 • ACR Convergence 2023

    Evaluation of the Pretest Probability Score, Ultrasound and Biopsy on GCA Diagnose: Data from Real Clinical Practice

    María del Carmen San José Méndez1, Uxía Couto Lareo1, Vanesa Balboa Barreiro2, Francisco J. Blanco1, Bruno de aspe de la iglesia1, Antonio Atanes Sandoval3, Diego Dios Santos1, Jesús Carlos Fernández López1, Mercedes Freire González1, Guillermo González Arribas1, Genaro Graña Gil1, Natividad Oreiro Villar1, Jose Antonio Pinto Tasende1, Francisco Javier De Toro Santos1, Clara Ventin Rodriguez1, Maite silva díaz3 and Ana Lois Iglesias1, 1Rheumatology department, Complexo Hospitalario Universitario A Coruña (CHUAC). Instituto de Investigación Biomédica A Coruña (INIBIC), A Coruña, Spain, 2Clinic epidemiology and biostatistics department. Complejo Hospitalario Universitario A Coruña (CHUAC). Instituto de Investigación Biomédica A Coruña (INIBIC), A Coruña, Spain, 3Rheumatology department, Complexo Hospitalario Universitario A Coruña (CHUAC). Instituto de Investigación Biomédica A Coruña (INIBIC)., A Coruña, Spain

    Background/Purpose: Giant cell arteritis (GCA) affects large and medium size arteries. Biopsy was considered the gold standard in the diagnosis1, but in the last years…
  • Abstract Number: 2485 • ACR Convergence 2023

    Comparative Risk of Serious Psychiatric Events with Belimumab versus Oral Immunosuppressant Use in Patients with Systemic Lupus Erythematosus

    April Jorge1, Baijun Zhou1, Yuqing Zhang2 and Hyon K. Choi3, 1Massachusetts General Hospital, Boston, MA, 2Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, 3Massachusetts General Hospital and Harvard Medical School, Lexington, MA

    Background/Purpose: In randomized placebo-controlled trials, including the phase 4 Belimumab Assessment of Safety in SLE study, belimumab use was associated with a higher incidence of…
  • Abstract Number: 0155 • ACR Convergence 2023

    Cost Analysis of Subcutaneous Methotrexate Compared to Oral Methotrexate Treatment for Rheumatoid Arthritis

    Aniket Kawatkar, David Yi, Erika Estrada and Cecilia Portugal, Kaiser Permanente Southern California, Pasadena, CA

    Background/Purpose: Rheumatoid Arthritis (RA)patients who switch from oral to subcutaneous methotrexate (MTX) may experience better response to treatment due to increased bioavailability, enhanced tolerability, increased…
  • Abstract Number: 2529 • ACR Convergence 2023

    Comparative Effectiveness of Denosumab versus Zoledronic Acid Among Postmenopausal Women with Osteoporosis in the U.S. Medicare Program

    Jeffrey R Curtis1, Tarun Arora2, Ye Liu3, Vanessa C. Brunetti4, Tzu-Chieh Lin4, Leslie Spangler4, Robert K. Stad4, Michele McDermott4, Brian D. Bradbury4 and Min Kim4, 1Division of Clinical Immunology and Rheumatology, University of Alabama, Birmingham, AL, 2Foundation for Advancing Science, Technology, Education, and Research, Birmingham, AL, 3University of Alabama at Birmingham, Birmingham, AL, 4Amgen, Inc., Thousand Oaks, CA

    Background/Purpose: Although clinical trials have shown that denosumab (Dmab) significantly increases bone mineral density at key skeletal sites more than zoledronic acid (ZA), evidence from…
  • Abstract Number: 0199 • ACR Convergence 2023

    Experience in Real-World Conditions of the Effectiveness of the Vaccine Against Herpes Zoster Virus

    Laura Mas Sanchez1, Pablo Francisco Muñoz Martínez2, Elena Grau Garcia3, Alba Maria Torrat Noves3, Daniel Ramos Castro3, Carmen Riesco Barcena3, Anderson Victor Huaylla Quispe3, Belen Villanueva Mañez3, Iago Alcantara Alvarez3, Samuel Leal Rodriguez3, Marta De la Rubia Navarro1, Ernesto Tovar Sugrañes3, Jose Ivorra Cortes3, Luis Gonzalez Puig3, Rosa Negueroles Albuixech3, Elvira Vicens Bernabeu3, Jose Eloy Oller Rodriguez3, Isabel Martinez Cordellat3, Hikmat Charia3, Ines Canovas Olmos3, Carmen Najera Herranz3 and Jose Andres Roman Ivorra4, 1Rheumatology Department. HUP La Fe, Valéncia, Spain, 2Rheumatology Department. HUP La Fe, Sagunto, Spain, 3Rheumatology Department. HUP La Fe, Valencia, Spain, 4Hospital Universitari i Politècnic la Fe, Valencia, Spain

    Background/Purpose: Herpes zoster infection is due to the reactivation of the varicella-zoster virus (VZV), having a high prevalence in elderly and immunocompromised patients. Since the…
  • Abstract Number: 2542 • ACR Convergence 2023

    Impact of Concomitant Methotrexate on Disease Activity After Tapering Abatacept in Patients with Rheumatoid Arthritis: A Nationwide Cohort Study

    Jun Won Park1, Min Jung Kim2, Hyoun-Ah Kim3, Jin Hyun Kim4 and Kichul Shin5, 1Seoul National University Hospital, Seoul, South Korea, 2Seoul Metropolitan Government Boramae Medical center, Dongjak-gu, Seoul, South Korea, 3Ajou University School of Medicine, Suwon, South Korea, 4Chungnam National University College of Medicine, Daejeon, South Korea, 5Seoul Metropolitan Government- Seoul National University Boramae Medical Center, Seoul, South Korea

    Background/Purpose: Recent randomized-controlled studies have suggested that tapering bDMARDs and/or csDMARDs after achieving sustained remission in patients with rheumatoid arthritis (RA) can be considered. However,…
  • Abstract Number: 0441 • ACR Convergence 2023

    Outcomes in Patients with Rheumatoid Arthritis Initiating Therapy with Etanercept, Adalimumab, or Janus Kinase Inhibitors

    Dimitrios Pappas1, Jacqueline O’Brien1, Lin Guo1, Ying Shan1, Joshua Baker2, Gregory Kricorian3, Scott Stryker4 and David Collier3, 1CorEvitas, LLC, Waltham, MA, 2University of Pennsylvania, Philadelphia, PA, 3Amgen, Inc., Thousand Oaks, CA, 4Amgen, Inc., San Francisco, CA

    Background/Purpose: Ongoing debate exists regarding the optimal sequence of tumor necrosis factor inhibitors and Janus kinase inhibitors (JAKis) in patients with rheumatoid arthritis (RA) as…
  • Abstract Number: 0606 • ACR Convergence 2023

    Risk of Damage Progression with Belimumab versus Oral Immunosuppressant Use in Patients with Systemic Lupus Erythematosus

    April Jorge1, Baijun Zhou1, Yuqing Zhang2 and Hyon K. Choi3, 1Massachusetts General Hospital, Boston, MA, 2Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, 3Massachusetts General Hospital and Harvard Medical School, Lexington, MA

    Background/Purpose: Belimumab was approved for the treatment of non-renal SLE in 2011 and has been previously associated with a lower risk of damage progression when…
  • Abstract Number: 0786 • ACR Convergence 2023

    A Retrospective Analysis of the Efficacy of the Euro-Lupus Nephritis Cyclophosphamide Regimen versus NIH Regimen in a South Carolina Lupus Nephritis Cohort

    Anna Arar, Diane L. Kamen, Paul Nietert and Melissa Cunningham, Medical University of South Carolina, Charleston, SC

    Background/Purpose: Manifestations of systemic lupus erythematous (SLE) vary in severity and presentation; lupus nephritis (LN) affects up to half of SLE patients and confers a…
  • Abstract Number: 0817 • ACR Convergence 2023

    Comparative Effectiveness of Yoga and Strengthening Exercise for Treating Knee OsteoArthritis: A Randomised Controlled Trial (YOGA Trial)

    Bedru Abafita1, Ambrish Singh1, Dawn Aitken1, Steffany Moonaz2, Andrew J Palmer1, Leigh Blizzard1, Changhai Ding1, Stan Drummen1, Graeme Jones3, Kim Bennell4 and Benny Samuel Antony1, 1Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, 2Department of Clinical and Health Services Research, Southern California University of Health Sciences, Whittier, CA, 3Menzies Institute for Medical Research, University of Tasmania, Melbourne, Australia, 4University of Melbourne, Melbourne, Australia

    Background/Purpose: There is uncertainty about the best type of exercise to optimise outcomes for people with knee osteoarthritis (OA). Strengthening exercise is commonly recommended. However,…
  • Abstract Number: 0831 • ACR Convergence 2023

    Two- and Three-Year Outcomes from the Childhood Arthritis and Rheumatology Research Alliance Start Time Optimization of Biologic Therapy in Polyarticular JIA (STOP-JIA) Study

    Sarah Ringold1, George Tomlinson2, Laura Schanberg3, vincent del gaizo4, Katherine Murphy5, Brian Feldman6, Mei-Sing Ong7, Marc Natter8, Yukiko Kimura9 and For The CARRA Registry Investgators4, 1Seattle Children's Hospital, Seattle, WA, 2University of Toronto, Toronto, ON, Canada, 3Duke University School of Medicine, Durham, NC, 4CARRA, Inc, Washington, DC, 5Non-clinical, New Orleans, LA, 6The Hospital for Sick Children, Toronto, ON, Canada, 7Harvard Medical School & Harvard Pilgrim Healthcare Institute, Boston, MA, 8Harvard Medical School, Boston, MA, 9Hackensack Meridian School of Medicine, New York, NY

    Background/Purpose: The STOP-JIA study was designed to compare the effectiveness of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Consensus Treatment Plans (CTPs) for untreated…
  • Abstract Number: 0973 • ACR Convergence 2023

    Real-World Comparative Effectiveness Study of Janus Kinase Inhibitors Compared to Biologic Disease Modifying Antirheumatic Drugs in Korean Patients with Rheumatoid Arthritis

    Soo-Kyung Cho1, Yeo-Jin Song1, Jungyong Han2, Hye Won Kim3, Eunwoo Nam3, Sang Won Lee4, Shin-Seok Lee5, Hye-Soon Lee6, Sung-Hoon Park7, Yeon-Ah Lee8, Sung Hae Chang9, Min-Chan Park10, Hyoun-Ah Kim11, Hyun-Sook Kim12, Bo Young Yoon13, Yong-Gil Kim14, Hae-Rim Kim15, Jae Hoon Kim16, Jisoo Lee17, Jeongim Choi18, Wan-Sik Uhm19 and Yoon-Kyoung Sung1, 1Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 2Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 3Hanyang University Institute for Rheumatology Research, Seoul, South Korea, 4Hanyang University, Seoul, South Korea, 5Chonnam National University Medical School & Hospital, Gwangju, South Korea, 6Hanyang University, Guri, South Korea, 7Daegu Catholic University School of Medicine, Daegu, South Korea, 8Kyung Hee University Hospital, Seoul, South Korea, 9Soonchunhyang University College of Medicine, Bongmyeong-dong, Dongnam-gu, Cheonan-si, South Korea, 10Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea, 11Ajou University School of Medicine, Suwon, South Korea, 12Soonchunhyang University Seoul Hospital, Seoul, South Korea, 13Inje University Ilsan Paik Hospital, Goyang, South Korea, 14Department of Rheumatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea, 15Rheumatology, Konkuk University Medical Center, Seoul, South Korea, 16Korea University Medical Center, Seoul, South Korea, 17Ewha Womans Univ College of Medicine, Seoul, South Korea, 18Busan Saint Mary's Hospital, Busan, South Korea, 19Uhm's Rheumatism Clinic, Seoul, South Korea

    Background/Purpose: Although clinical trials have shown similar effectiveness between Janus kinase inhibitors (JAKi) and biologic disease-modifying anti-rheumatic drugs (bDMARDs), the choice between these two options…
  • Abstract Number: 1117 • ACR Convergence 2023

    Serum Urate Change Among Gout Patients Initiating Sodium-Glucose Cotransporter Type 2 Inhibitors (SGLT2i) vs. Sulfonylureas: A Comparative Effectiveness Analysis

    Chio Yokose1, Gregory Challener2, Baijun Zhou2, Natalie McCormick2, Sruthi Tanikella2, Kila Panchot2, Minna Kohler3, Janeth Yinh2, Yuqing Zhang4, David Bates5, James Januzzi2, Meghan Sise2, Deborah Wexler2 and Hyon K. Choi6, 1Massachusetts General Hospital, Waltham, MA, 2Massachusetts General Hospital, Boston, MA, 3Massachusetts General Hospital, Harvard Medical School, Boston, MA, 4Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, 5Brigham and Women's Hospital, Boston, MA, 6Massachusetts General Hospital and Harvard Medical School, Lexington, MA

    Background/Purpose: Sodium-glucose cotransporter type 2 inhibitors (SGLT2i) are currently indicated as second-line therapy for type 2 diabetes and are also approved for the treatment of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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