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Abstracts tagged "combination therapies and comparative effectiveness and harms"

  • Abstract Number: 1518 • 2019 ACR/ARP Annual Meeting

    Tumour Necrosis Factor Inhibitor Monotherapy versus Combination Therapy with Conventional Synthetic Disease-modifying Anti-rheumatic Drugs for the Treatment of Psoriatic Arthritis: A Combined Analysis of European Biologics Databases

    Matthew Thomas 1, Gavin Shaddick 2, Rachel Charlton 1, Charlotte Cavill 3, Richard Holland 4, Florenzo Iannone 5, Giovanni Lapadula 6, Simona Lapriore 5, Jakub Závada 7, Michal Uher 8, Karel Pavelka 9, Lenka Szczukova 10, Prodromos Sidiropolous 11, Irini Flouri 11, Burkhard Moeller 12, Michael J. Nissen 13, Ruediger B. Mueller 14, Almut Scherer 15, Neil McHugh1 and Alison Nightingale 1, 1University of Bath, Bath, United Kingdom, 2University of Exeter, Exeter, United Kingdom, 3Royal National Hospital for Rheumatic Diseases, Royal United Hospitals NHS Trust, Bath, United Kingdom, 4Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 5University of Bari, Bari, Italy, 6Rheumatology Unit – Department of Emergency and Organs Transplantation, University and AOU Policlinico of Bari, Italy., Bari, Italy, 7Institute of Rheumatology, Prague, Prague, Czech Republic, 8Institute of Health Information and Statistics of the Czech Republic, and Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic, Brno, Czech Republic, 9Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague 2, Czech Republic, 10Masaryk University, Brno, Czech Republic, 11University of Crete, Crete, Greece, 12University Hospital Bern, Bern, Switzerland, 13University Hospital Geneva, Geneva, Switzerland, 14Clinic of Rheumatology, Medical University Hospital Aarau, Aarau, Aargau, Switzerland, 15SCQM Foundation, Zürich, Switzerland

    Background/Purpose: A large proportion of psoriatic arthritis (PsA) patients are prescribed a tumour necrosis factor inhibitor (TNFi) in combination with methotrexate (MTX), however the value…
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