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Abstracts tagged "collagen and anti-TNF therapy"

  • Abstract Number: 583 • ACR/ARP Annual Meeting 2019

    A Biomarker of Type VI Collagen Degradation (C6M) Is Associated with Changes in ASDAS MRI Measures of Inflammation in Patients with Axial Spondyloarthritis During TNF Inhibitor Therapy

    Signe Holm Nielsen1, Anne Bay-Jensen 2, Mikkel Østergaard 3, Anne Siebuhr 4, Morten Karsdal 5, inge Juul Sørensen 6, Ulrich Weber 7, Anne Gitte Loft 8, Gina Kollerup 9, Gorm Thamsborg 9, Ole Rintek Madsen 10, Jakob Møller 11 and Susanne Juhl Pedersen 12, 1Nordic Bioscience/Technical University of Denmark, Herlev, Denmark, 2Nordic Bioscience, Herlev, Denmark, 3Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark, 4Nordic Bioscience, Herlev, 5Nordic Bioscience, Copenhagen, Denmark, 6Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, Glostrup, Denmark, 7Danish Hospital for Rheumatic Diseases, University Hospital of Southern Denmark, Sonderborg, Denmark, 8Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, Århus, Denmark, 9Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Hovedstaden, Denmark, 10Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, 11Department of Radiology, Herlev and Gentofte University Hospital, Herlev, Denmark, Copenhagen, Denmark, 12Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Hovedstaden, Denmark

    Background/Purpose: Axial spondyloarthritis (AxSpa) is characterized by inflammation in the sacroiliac joints and spine and associated with extracellular matrix (ECM) remodelling of affected tissues. Type…

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