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Abstracts tagged "Cognitive dysfunction and systemic lupus erythematosus (SLE)"

  • Abstract Number: 1621 • 2019 ACR/ARP Annual Meeting

    The Impact of Disease Activity and Related Factors on Cognitive Dysfunction in SLE

    Erik Anderson1, Elisabeth Ploran 2, Joseph Hong 3, Betty Diamond 4, Bruce Volpe 5, Cynthia Aranow 6 and Meggan Mackay 7, 1Northwell Health System, Feinstein Institute for Medical Research, New York, 2Hofstra University, Hempstead, 3Northwell Health System, Feinstein Institute for Medical Research, Manhasset, 4Feinstein Institutes for Medical Research, Manhasset, 5Feinstein Institutes for Medical Research, Manhasset, NY, 6Feinstein Institute for Medical Research, Manhasset, NY, 7Feinstein Institute for Medical Research, New York

    Background/Purpose: Attribution of cognitive dysfunction (CD) to SLE is compromised by potential confounders. Studies reveal conflicting results on the relationship between CD and disease activity,…
  • Abstract Number: 708 • 2018 ACR/ARHP Annual Meeting

    The Montreal Cognitive Assessment Test. a Useful Tool in Screening of Cognitive Impairment in Patients with Systemic Lupus Erythematosusshort Title: Cognitive Impairment in SLE

    Nicolas Paez-Venegas1, Bethel Jordan-Estrada2, Efrain Chavarria-Avila2, Felipe Perez-Vazquez2, Eduardo Gomez-Bañuelos3, Rafael Medina-Davalos1, Jose A. Ontiveros-Gonzalez4, Gustavo I Diaz-Rubio2, Rosa E Navarro-Hernandez2 and Monica Vazquez-Del Mercado3, 1Instituto Jalisciense de Salud Mental, ZAPOPAN, Mexico, 2Centro Universitario de Ciencias de la Salud, Instituto de Investigación en Reumatología y del Sistema Músculo Esquelético, Universidad de Guadalajara, Guadalajara, Mexico, 3Servicio de Reumatología, 004086 PNPC CONACyT, Hospital Civil de Guadalajara Dr. Juan I. Menchaca, Guadalajara, Mexico, 4Hospital Civil de Guadalajara Dr. Juan I. Menchaca, Guadalajara, Mexico

    Background/Purpose: Systemic lupus erythematosus (SLE) is an inflammatory, chronic and multisystemic disease, which can be related with a long range of neuropsychiatric manifestations, including cognitive…
  • Abstract Number: 771 • 2018 ACR/ARHP Annual Meeting

    Does Cognitive Function Change over-Time in Systemic Lupus Erythematosus?

    Zahi Touma1, Robin Green2, Carmela Tartaglia3, Lesley Ruttan4, Sabrina Lombardi5, Nicole Anderson6, Jiandong Su1, Kenneth Colosimo4, Michelle Vitti1, Joan E. Wither7, Marvin J. Fritzler8 and Dorcas Beaton9, 1University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Brain and Therapeutics, Toronto Rehabilitation Institute, Toronto, ON, Canada, 3University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada, 4Toronto Rehabilitation Institute, Toronto, ON, Canada, 5Psychology & Neuropsychology Complex Injury, Toronto Rehabilitation Institute, Toronto, ON, Canada, 6Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 7Department of Immunology, Department of Immunology, University of Toronto, Toronto, ON, Canada, 8Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 9Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada

    Background/Purpose: Cognitive impairment (CI) is a common neurobehavioral manifestation of SLE. In our recent systematic review, the prevalence of CI was 38% (95% CI: 33-43%).…
  • Abstract Number: 1621 • 2017 ACR/ARHP Annual Meeting

    Prevalence of Cognitive Impairment in Systemic Lupus Erythematosus Assessed By the Automated Neuropsychological Assessment Metrics

    Zahi Touma1, Robin Green2, Lesley Ruttan3, Sabrina Lombardi3, Carmela Tartaglia4, Nicole Anderson5, Jiandong Su6, Kenneth Colosimo6, Michelle Vitti6, Dennisse Bonilla6, Joan E. Wither5, Marvin J. Fritzler7 and Dorcas Beaton8, 1Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada, 2Brain and Therapeutics, Toronto Rehabilitation Institute, Toronto, ON, Canada, 3Toronto Rehabilitation Institute, Toronto, ON, Canada, 4University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada, 5Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 6University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 7Medicine, University of Calgary, Calgary, AB, Canada, 8Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada

    Background/Purpose: The screening and diagnosis of Cognitive Impairment (CI) in Systemic Lupus Erythematosus (SLE) patients is often delayed. CI diagnosed according to the American College…
  • Abstract Number: 1650 • 2017 ACR/ARHP Annual Meeting

    The Montreal Cognitive Assessment Questionnaire (MoCA): A Promising Screening Tool for Cognitive Dysfunction in SLE

    Nathalie Chalhoub and Michael Luggen, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH

    Background/Purpose: Cognitive dysfunction (CD) is among the most common neuropsychiatric manifestations in SLE. However, the diagnosis is oftentimes delayed and occasionally overlooked because of the…
  • Abstract Number: 2807 • 2017 ACR/ARHP Annual Meeting

    Can the Automated Neuropsychological Assessment Metrics (ANAM) Predict Cognitive Impairment Compared to a Comprehensive Neuropsychological Battery in Patients with Lupus?

    Zahi Touma1, Dorcas Beaton2, Carmela Tartaglia3, Lesley Ruttan4, Sabrina Lombardi4, Nicole Anderson5, Jiandong Su6, Kenneth Colosimo7, Michelle Vitti7, Dennisse Bonilla8, Joan E. Wither9, Marvin J. Fritzler10 and Robin Green11, 1Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada, 2Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada, 3University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada, 4Toronto Rehabilitation Institute, Toronto, ON, Canada, 5Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, 6Rheumatology, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, 7University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 8Krembil Research Institute, University Health Network, Toronto, ON, Canada, 9Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 10Medicine, University of Calgary, Calgary, AB, Canada, 11Brain and Therapeutics, Toronto Rehabilitation Institute, Toronto, ON, Canada

    Background/Purpose: Currently, the diagnosis of cognitive impairment (CI) is often delayed requiring use of a comprehensive battery (CB) which imposes a time- and cost-burden. It…
  • Abstract Number: 2808 • 2017 ACR/ARHP Annual Meeting

    Longitudinal Assessment of Cognitive Function in SLE: Identification of Trajectories

    Zahi Touma1, Jiandong Su2 and Patricia P. Katz3, 1Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada, 2University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA

    Background/Purpose: Cognitive function may change over time in patients with SLE, and cognitive function trajectories (CFTs) have not well been studied. This is the first…
  • Abstract Number: 2955 • 2015 ACR/ARHP Annual Meeting

    Cognitive Impairment in Lupus Patients: Identification of the Best Screening Test and Assessment for Associated Factors

    Stephanie Nantes1, Murray Urowitz2,3, Dafna Gladman2, Jiandong Su2, Ashneet Dhaliwal1 and Zahi Touma2, 1University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Rheumatology, U of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose:   There is an unmet need for a screening test of cognitive function that can be administered in clinic in patients with SLE. We…
  • Abstract Number: 2957 • 2015 ACR/ARHP Annual Meeting

    25-Hydroxyvitamin D3 Deficiency Independently Predicts Cognitive Impairment in Patients with Systemic Lupus Erythematosus: Results from a Controlled Study

    Sen Hee Tay1,2 and Anselm Mak2,3, 1National University of Singapore, Singapore, Singapore, 2National University Health System, Singapore, Singapore, 3Medicine, National University of Singapore, Singapore, Singapore

    Background/Purpose: Cognitive dysfunction has been reported in 20-80% of systemic lupus erythematosus (SLE) patients.  Converging evidence has indicated the importance of vitamin D as a…
  • Abstract Number: 2649 • 2014 ACR/ARHP Annual Meeting

    “Point of Care” Neurocognitive Testing for Neuropsychiatric Systemic Lupus Erythematosis (NPSLE)

    Debbie Rybak1, Nicole Jordan1, Noa Schwartz1, Tamar Rubinstein2, Bryan Freilich3, Irene Blanco4 and Chaim Putterman5, 1Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, 2Pediatric Rheumatology, Albert Einstein College of Medicine, Bronx, NY, 3Psychiatry, Albert Einstein College of Medicine, Bronx, NY, 4Rheumatology, Albert Einstein College of Medicine, Bronx, NY, 5The Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY

    Background/Purpose There is currently no standardized tool to assess for NPSLE, and comprehensive neuropsychological testing can be lengthy and expensive. The Automated Neuropsychological Assessment Metric…
  • Abstract Number: 2650 • 2014 ACR/ARHP Annual Meeting

    Cognitive Impairment in SLE and Non-Criterion Anti-Phospholipid Antibodies

    Michael Luggen1, Gaurav Gulati2, Rohan Willis3 and Emilio B. Gonzalez3, 1Division of Immunology, Allergy, and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH, 2Division of Immunology, Allergy & Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH, 3Rheumatolgoy/Dept Int Med, University of Texas Medical Branch, Galveston, TX

    Background/Purpose: The pathogenesis of cognitive impairment (CI) in patients with SLE is unknown. Anti-phospholipid antibodies (APL) have been implicated in some studies, but not in…
  • Abstract Number: 1258 • 2013 ACR/ARHP Annual Meeting

    Cognitive Functions In Childhood-Onset Systemic Lupus Erythematosus

    Bruna Bellini1, Cleonice de Souza1, Mariana Postal1, Nailu A. Sinicato1, Paula T Fernandes2, Roberto Marini3 and Simone Appenzeller4, 1Medicine, State University of Campinas, Campinas, Brazil, 2Faculty of Physical Education, State University of Campinas, Campinas, Brazil, 3State University of Campinas, Campinas, Brazil, 4Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil

    Background/Purpose: To determine differences in cognitive functions in childhood-onset systemic lupus erythematosus (cSLE).  Methods: We performed a cross-sectional study including patients with age of onset…
  • Abstract Number: 1259 • 2013 ACR/ARHP Annual Meeting

    Cognitive Dysfunction In Childhood Systemic Lupus Erythematosus: Comparison Of Different Classification Criteria

    Bruna Bellini1, Cleonice de Souza1, Mariana Postal1, Nailu A. Sinicato1, Roberto Marini2, Paula T Fernandes3 and Simone Appenzeller4, 1Medicine, State University of Campinas, Campinas, Brazil, 2State University of Campinas, Campinas, Brazil, 3Faculty of Physical Education, State University of Campinas, Campinas, Brazil, 4Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil

    Background/Purpose: Cognitive deficits are frequently observed in systemic lupus erythematosus (SLE), in both adult and childhood (cSLE) onset. However there are several different cutoff levels…
  • Abstract Number: 300 • 2012 ACR/ARHP Annual Meeting

    Prevalence and Clinical Significance of Hippocampal Atrophy in Childhood-Onset Systemic Lupus Erythematosus

    Aline T. Lapa1, Renata Brabosa2, Mariana Postal1, Nailu A. Sinicato1, Roberto Marini3, Fernando Cendes4 and Simone Appenzeller5, 1Medicine, State University of Campinas, Campinas, Brazil, 2Medicine, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, Germany, 3State University of Campinas, Campinas, Brazil, 4Neurology, State University of Campinas, Campinas, Brazil, 5Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil

    Background/Purpose: Hippocampal atrophy is associated with corticosteroid use and may be related to cognitive impairment in systemic lupus erythematosus (SLE).Objectives: To determine the prevalence of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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