Abstracts tagged "Cognitive dysfunction and systemic lupus erythematosus (SLE)"

Abstract Number: 1621 • 2019 ACR/ARP Annual Meeting
The Impact of Disease Activity and Related Factors on Cognitive Dysfunction in SLE
Erik Anderson¹, Elisabeth Ploran ², Joseph Hong ³, Betty Diamond ⁴, Bruce Volpe ⁵, Cynthia Aranow ⁶ and Meggan Mackay ⁷, ¹Northwell Health System, Feinstein Institute for Medical Research, New York, ²Hofstra University, Hempstead, ³Northwell Health System, Feinstein Institute for Medical Research, Manhasset, ⁴Feinstein Institutes for Medical Research, Manhasset, ⁵Feinstein Institutes for Medical Research, Manhasset, NY, ⁶Feinstein Institute for Medical Research, Manhasset, NY, ⁷Feinstein Institute for Medical Research, New York
Background/Purpose: Attribution of cognitive dysfunction (CD) to SLE is compromised by potential confounders. Studies reveal conflicting results on the relationship between CD and disease activity,…
Abstract Number: 771 • 2018 ACR/ARHP Annual Meeting
Does Cognitive Function Change over-Time in Systemic Lupus Erythematosus?
Zahi Touma¹, Robin Green², Carmela Tartaglia³, Lesley Ruttan⁴, Sabrina Lombardi⁵, Nicole Anderson⁶, Jiandong Su¹, Kenneth Colosimo⁴, Michelle Vitti¹, Joan E. Wither⁷, Marvin J. Fritzler⁸ and Dorcas Beaton⁹, ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Brain and Therapeutics, Toronto Rehabilitation Institute, Toronto, ON, Canada, ³University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada, ⁴Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁵Psychology & Neuropsychology Complex Injury, Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁶Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁷Department of Immunology, Department of Immunology, University of Toronto, Toronto, ON, Canada, ⁸Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁹Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada
Background/Purpose: Cognitive impairment (CI) is a common neurobehavioral manifestation of SLE. In our recent systematic review, the prevalence of CI was 38% (95% CI: 33-43%).…
Abstract Number: 708 • 2018 ACR/ARHP Annual Meeting
The Montreal Cognitive Assessment Test. a Useful Tool in Screening of Cognitive Impairment in Patients with Systemic Lupus Erythematosusshort Title: Cognitive Impairment in SLE
Nicolas Paez-Venegas¹, Bethel Jordan-Estrada², Efrain Chavarria-Avila², Felipe Perez-Vazquez², Eduardo Gomez-Bañuelos³, Rafael Medina-Davalos¹, Jose A. Ontiveros-Gonzalez⁴, Gustavo I Diaz-Rubio², Rosa E Navarro-Hernandez² and Monica Vazquez-Del Mercado³, ¹Instituto Jalisciense de Salud Mental, ZAPOPAN, Mexico, ²Centro Universitario de Ciencias de la Salud, Instituto de Investigación en Reumatología y del Sistema Músculo Esquelético, Universidad de Guadalajara, Guadalajara, Mexico, ³Servicio de Reumatología, 004086 PNPC CONACyT, Hospital Civil de Guadalajara Dr. Juan I. Menchaca, Guadalajara, Mexico, ⁴Hospital Civil de Guadalajara Dr. Juan I. Menchaca, Guadalajara, Mexico
Background/Purpose: Systemic lupus erythematosus (SLE) is an inflammatory, chronic and multisystemic disease, which can be related with a long range of neuropsychiatric manifestations, including cognitive…
Abstract Number: 1621 • 2017 ACR/ARHP Annual Meeting
Prevalence of Cognitive Impairment in Systemic Lupus Erythematosus Assessed By the Automated Neuropsychological Assessment Metrics
Zahi Touma¹, Robin Green², Lesley Ruttan³, Sabrina Lombardi³, Carmela Tartaglia⁴, Nicole Anderson⁵, Jiandong Su⁶, Kenneth Colosimo⁶, Michelle Vitti⁶, Dennisse Bonilla⁶, Joan E. Wither⁵, Marvin J. Fritzler⁷ and Dorcas Beaton⁸, ¹Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada, ²Brain and Therapeutics, Toronto Rehabilitation Institute, Toronto, ON, Canada, ³Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁴University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada, ⁵Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁶University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁷Medicine, University of Calgary, Calgary, AB, Canada, ⁸Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada
Background/Purpose: The screening and diagnosis of Cognitive Impairment (CI) in Systemic Lupus Erythematosus (SLE) patients is often delayed. CI diagnosed according to the American College…
Abstract Number: 1650 • 2017 ACR/ARHP Annual Meeting
The Montreal Cognitive Assessment Questionnaire (MoCA): A Promising Screening Tool for Cognitive Dysfunction in SLE
Nathalie Chalhoub and Michael Luggen, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH
Background/Purpose: Cognitive dysfunction (CD) is among the most common neuropsychiatric manifestations in SLE. However, the diagnosis is oftentimes delayed and occasionally overlooked because of the…
Abstract Number: 2807 • 2017 ACR/ARHP Annual Meeting
Can the Automated Neuropsychological Assessment Metrics (ANAM) Predict Cognitive Impairment Compared to a Comprehensive Neuropsychological Battery in Patients with Lupus?
Zahi Touma¹, Dorcas Beaton², Carmela Tartaglia³, Lesley Ruttan⁴, Sabrina Lombardi⁴, Nicole Anderson⁵, Jiandong Su⁶, Kenneth Colosimo⁷, Michelle Vitti⁷, Dennisse Bonilla⁸, Joan E. Wither⁹, Marvin J. Fritzler¹⁰ and Robin Green¹¹, ¹Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada, ²Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada, ³University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada, ⁴Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁵Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁶Rheumatology, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁷University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁸Krembil Research Institute, University Health Network, Toronto, ON, Canada, ⁹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ¹⁰Medicine, University of Calgary, Calgary, AB, Canada, ¹¹Brain and Therapeutics, Toronto Rehabilitation Institute, Toronto, ON, Canada
Background/Purpose: Currently, the diagnosis of cognitive impairment (CI) is often delayed requiring use of a comprehensive battery (CB) which imposes a time- and cost-burden. It…
Abstract Number: 2808 • 2017 ACR/ARHP Annual Meeting
Longitudinal Assessment of Cognitive Function in SLE: Identification of Trajectories
Zahi Touma¹, Jiandong Su² and Patricia P. Katz³, ¹Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada, ²University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA
Background/Purpose: Cognitive function may change over time in patients with SLE, and cognitive function trajectories (CFTs) have not well been studied. This is the first…
Abstract Number: 2955 • 2015 ACR/ARHP Annual Meeting
Cognitive Impairment in Lupus Patients: Identification of the Best Screening Test and Assessment for Associated Factors
Stephanie Nantes¹, Murray Urowitz^2,3, Dafna Gladman², Jiandong Su², Ashneet Dhaliwal¹ and Zahi Touma², ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Rheumatology, U of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: There is an unmet need for a screening test of cognitive function that can be administered in clinic in patients with SLE. We…
Abstract Number: 2957 • 2015 ACR/ARHP Annual Meeting
25-Hydroxyvitamin D3 Deficiency Independently Predicts Cognitive Impairment in Patients with Systemic Lupus Erythematosus: Results from a Controlled Study
Sen Hee Tay^1,2 and Anselm Mak^2,3, ¹National University of Singapore, Singapore, Singapore, ²National University Health System, Singapore, Singapore, ³Medicine, National University of Singapore, Singapore, Singapore
Background/Purpose: Cognitive dysfunction has been reported in 20-80% of systemic lupus erythematosus (SLE) patients. Converging evidence has indicated the importance of vitamin D as a…
Abstract Number: 2650 • 2014 ACR/ARHP Annual Meeting
Cognitive Impairment in SLE and Non-Criterion Anti-Phospholipid Antibodies
Michael Luggen¹, Gaurav Gulati², Rohan Willis³ and Emilio B. Gonzalez³, ¹Division of Immunology, Allergy, and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH, ²Division of Immunology, Allergy & Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH, ³Rheumatolgoy/Dept Int Med, University of Texas Medical Branch, Galveston, TX
Background/Purpose: The pathogenesis of cognitive impairment (CI) in patients with SLE is unknown. Anti-phospholipid antibodies (APL) have been implicated in some studies, but not in…
Abstract Number: 2649 • 2014 ACR/ARHP Annual Meeting
“Point of Care” Neurocognitive Testing for Neuropsychiatric Systemic Lupus Erythematosis (NPSLE)
Debbie Rybak¹, Nicole Jordan¹, Noa Schwartz¹, Tamar Rubinstein², Bryan Freilich³, Irene Blanco⁴ and Chaim Putterman⁵, ¹Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ²Pediatric Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ³Psychiatry, Albert Einstein College of Medicine, Bronx, NY, ⁴Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ⁵The Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY
Background/Purpose There is currently no standardized tool to assess for NPSLE, and comprehensive neuropsychological testing can be lengthy and expensive. The Automated Neuropsychological Assessment Metric…
Abstract Number: 1258 • 2013 ACR/ARHP Annual Meeting
Cognitive Functions In Childhood-Onset Systemic Lupus Erythematosus
Bruna Bellini¹, Cleonice de Souza¹, Mariana Postal¹, Nailu A. Sinicato¹, Paula T Fernandes², Roberto Marini³ and Simone Appenzeller⁴, ¹Medicine, State University of Campinas, Campinas, Brazil, ²Faculty of Physical Education, State University of Campinas, Campinas, Brazil, ³State University of Campinas, Campinas, Brazil, ⁴Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil
Background/Purpose: To determine differences in cognitive functions in childhood-onset systemic lupus erythematosus (cSLE). Methods: We performed a cross-sectional study including patients with age of onset…
Abstract Number: 1259 • 2013 ACR/ARHP Annual Meeting
Cognitive Dysfunction In Childhood Systemic Lupus Erythematosus: Comparison Of Different Classification Criteria
Bruna Bellini¹, Cleonice de Souza¹, Mariana Postal¹, Nailu A. Sinicato¹, Roberto Marini², Paula T Fernandes³ and Simone Appenzeller⁴, ¹Medicine, State University of Campinas, Campinas, Brazil, ²State University of Campinas, Campinas, Brazil, ³Faculty of Physical Education, State University of Campinas, Campinas, Brazil, ⁴Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil
Background/Purpose: Cognitive deficits are frequently observed in systemic lupus erythematosus (SLE), in both adult and childhood (cSLE) onset. However there are several different cutoff levels…
Abstract Number: 300 • 2012 ACR/ARHP Annual Meeting
Prevalence and Clinical Significance of Hippocampal Atrophy in Childhood-Onset Systemic Lupus Erythematosus
Aline T. Lapa¹, Renata Brabosa², Mariana Postal¹, Nailu A. Sinicato¹, Roberto Marini³, Fernando Cendes⁴ and Simone Appenzeller⁵, ¹Medicine, State University of Campinas, Campinas, Brazil, ²Medicine, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, Germany, ³State University of Campinas, Campinas, Brazil, ⁴Neurology, State University of Campinas, Campinas, Brazil, ⁵Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil
Background/Purpose: Hippocampal atrophy is associated with corticosteroid use and may be related to cognitive impairment in systemic lupus erythematosus (SLE).Objectives: To determine the prevalence of…

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