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Abstracts tagged "CNS Lupus and SLE"

  • Abstract Number: 937 • ACR/ARHP Annual Meeting 2018

    Evidence of a Common Microglial Signature in Models of ‘Neuropsychiatric Symptoms of Systemic Lupus Erythematosus’

    Hadijat M. Makinde1, Elise V. Mike2, Deborah R. Winter3, Chaim Putterman4 and Carla M. Cuda3, 1Northwestern University Feinberg School of Medicine, Chicago, IL, 2Albert Einstein College of Medicine, Bronx, NY, 3Department of Medicine Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 4Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, USA, Bronx, NY

    Background/Purpose: Systemic lupus erythematosus (SLE) is a complex autoimmune syndrome affecting multiple organs, including the brain. More than 60% of patients experience neuropsychiatric symptoms of…
  • Abstract Number: 1852 • ACR/ARHP Annual Meeting 2015

    Association of Antibodies to the NR1 Subunit of N-Methyl-D-Aspartate Receptors with Neuropsychiatric Systemic Lupus Erythematosus

    Eisuke Ogawa1, Tatsuo Nagai2, Yuko Sakuma3, Yoshiyuki Arinuma4 and Shunsei Hirohata4, 1Int Med/Rheumatol & Infec Dis, Kitasato University School of Medicine, Sagamihara, Japan, 2Department of Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Sagamihara, Japan, 3Department of Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan, 4Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan

    Background/Purpose: To explore the roles of autoantibodies to N-methyl-D-aspartate (NMDA) receptor NR1 subunit in the pathogenesis of neuropsychiatric systemic lupus erythematosus (NPSLE).Methods: Paired serum and…
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