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Abstracts tagged "CNS Lupus and immunoregulation"

  • Abstract Number: 2117 • ACR/ARHP Annual Meeting 2018

    Neuropsychiatric Systemic Lupus Erythematosus Is Attenuated By Sphingosine-1-Phosphate Receptor Modulation

    Elise Mike1, Carla M. Cuda2, Hadijat M. Makinde3, Harris Perlman4 and Chaim Putterman5, 1Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, 2Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Northwestern University Feinberg School of Medicine, Chicago, IL, 4Department of Medicine Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 5Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, USA, Bronx, NY

    Background/Purpose: About 20-40% of lupus patients suffer from diffuse neuropsychiatric manifestations of SLE, including cognitive impairment and depression. Although the pathogenesis is not well understood,…

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