Abstracts tagged "clinical trials and renal disease"

Abstract Number: 866 • 2019 ACR/ARP Annual Meeting
Evaluation of the Highly Selective Endothelin a Receptor Antagonist Zibotentan in Systemic Sclerosis Associated Chronic Kidney Disease
Edward Stern ¹, Lauren Host ¹, K. Jane Escott ², Peter Gilmour ², Ivy Wanjiku ³, Rachel Ochiel ³, Aine Burns ¹, Robert Unwin ¹, Voon Ong ⁴ and Christopher Denton⁵, ¹University College London, London, United Kingdom, ²AstraZeneca, London, United Kingdom, ³Royal Free Hospital, London, United Kingdom, ⁴UCL Medical School, Royal Free Campus, London, ⁵University College London Division of Medicine, Centre for Rheumatology and Connective Tissue Diseases, London, UK, London, United Kingdom
Background/Purpose: Systemic sclerosis (SSc) causes scleroderma renal crisis (SRC) and chronic kidney disease (CKD). A previous open label trial of bosentan suggested possible benefit for…

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Abstracts tagged "clinical trials and renal disease"

Evaluation of the Highly Selective Endothelin a Receptor Antagonist Zibotentan in Systemic Sclerosis Associated Chronic Kidney Disease