Abstracts tagged "clinical trials and polymyalgia rheumatica"

Abstract Number: 885 • 2014 ACR/ARHP Annual Meeting
A 2-Week Single-Blind, Randomized, 3-Arm Proof of Concept Study of the Effects of Secukinumab (anti-IL17 mAb), Canakinumab (anti-IL-1 b mAb), or Corticosteroids on Initial Disease Activity Scores in Patients with PMR, Followed By an Open-Label Extension to Assess Safety and Effect Duration
Eric L. Matteson¹, Bhaskar Dasgupta², Wolfgang A. Schmidt³, Carlo Salvarani⁴, Nagui Gendi⁵, Mauro Galeazzi⁶, Sylvie Stitah⁷, Yue Li⁸, Marie-Anne Valentin⁹, Bolan Linghu¹⁰ and Stephen J. Oliver⁷, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Rheumatology, Southend University Hospital, Essex, United Kingdom, ³Rheumatology, Immanuel Krankenhaus, Berlin, Germany, ⁴Rheumatology Unit, Arcispedale-Santa-Maria-Nuova, Reggio Emilia, Italy, ⁵Rheumatology, Basildon & Thurroch University Hospitals NHS Trust, Basildon, Essex, United Kingdom, ⁶Sezione di Reumatologia, Università di Siena, Siena, Italy, ⁷Translational Medicine, Novartis Pharma AG, Basel, Switzerland, ⁸IIS, Novartis Pharma AG, Basel, Switzerland, ⁹Biomarker Development, Novartis Pharma AG, Basel, Switzerland, ¹⁰Translational Medicine, Novartis Pharma AG, Cambridge, MA
Background/Purpose To assess the effects of a single dose of secukinumab or canakinumab in patients with new onset, untreated polymyalgia rheumatica (PMR). Methods In this…

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