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Abstracts tagged "Clinical research and pharmacokinetics"

  • Abstract Number: 1620 • 2016 ACR/ARHP Annual Meeting

    Pharmacokinetics, Pharmacodynamics, and Immunogenicity of MEDI4920, a Novel, Engineered CD40 Ligand Antagonist, in Healthy Volunteers

    Jing Li1, Michele Gunsior2, Neang Ly1, Alex Godwood3, David Howe3, Marius Albulescu3, Lisa H Butler3, Krista Arbaugh2 and Raffaella Faggioni1, 1MedImmune, Mountain View, CA, 2MedImmune, Gaithersburg, MD, 3MedImmune, Cambridge, United Kingdom

    Background/Purpose:  Fifty-six healthy adult male subjects were randomized in the study at a single site and administered either placebo or MEDI4920 (3, 10, 30, 100,…
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