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Abstracts tagged "Clinical practice"

  • Abstract Number: 2666 • 2015 ACR/ARHP Annual Meeting

    Trajectories of EQ-5D in RA Patients Treated with Biologics Using the IORRA Cohort

    Daisuke Hoshi, Eiichi Tanaka, Eisuke Inoue, Yoko Shimizu, Naoki Sugimoto, Kumi Shidara, Ayako Nakajima, Shigeki Momohara, Atsuo Taniguchi and Hisashi Yamanaka, Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan

    Background/Purpose: Patient-reported outcomes are recognized as important for evaluating the disease status of rheumatoid arthritis (RA). The EuroQol 5-dimensional descriptive system (EQ-5D) has been used…
  • Abstract Number: 433 • 2015 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis (RA) Biologic Switching and Cycling in a Large US Managed Care Population

    Machaon Bonafede1, Jeffrey R. Curtis2, Donna McMorrow1, Chieh-I Chen3 and George J. Joseph4, 1Truven Health Analytics, Cambridge, MA, 2Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 3Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 4Global Health Economics & Outcomes Research (HEOR), Sanofi, Bridgewater, NJ

    Background/Purpose: A majority of RA patients who switch from a tumor necrosis factor inhibitor (TNFi) to another biologic disease-modifying anti-rheumatic drug (DMARD) are TNFi cyclers…
  • Abstract Number: 2729 • 2015 ACR/ARHP Annual Meeting

    Clinical and Radiographic Outcome of Iguratimod for Rheumatoid Arthritis

    Tsuneo Kondo, Akiko Shibata, Ryota Sakai, Jun Kikuchi, Kentaro Chino, Ayumi Okuyama, Hirofumi Takei and Koichi Amano, Department of Rheumatology and Clinical Immunology, Saitama Medical Center, Saitama Medical University, Saitama, Japan

    Background/Purpose: Iguratimod is a new small-molecular drug for rheumatoid arthritis (RA), which was approved on June, 2012 in Japan. The agent inhibits the production of…
  • Abstract Number: 448 • 2015 ACR/ARHP Annual Meeting

    A Majority of Early Rheumatoid Arthritis (ERA) Patients Reach Remission By 6 Months in Usual Rheumatology Care

    Tuomas Rannio1, Juha Asikainen2, Pekka Hannonen3, Timo Yli-Kerttula4, Päivi Ekman5, Laura Pirilä6, Markku Mali7, Laura Kuusela7, Maija Puurtinen-Vilkki7, Saara Kortelainen8, Johanna Paltta7, Kirsi Taimen7, Heidi Mäkinen9, Pia Isomäki9, Terhi Uotila9, Markku J. Kauppi10, Kari Laiho11, Satu Nyrhinen11, Tuulikki Sokka-Isler1 and FIN-ERA study group, 1Rheumatology, Jyvaskyla Central Hospital, Jyvaskyla, Finland, 2Jyväskylä Central Hospital, Jyväskylä, Finland, 3Jyvaskyla Central Hospital, Jyvaskyla, Finland, 4Sairaalantie 3, Central Hospital of Satakunta, Pori, Finland, 5Central Hospital of Satakunta, Pori, Finland, 6Tyks, P.O. Box 52, Turku University Central Hospital, Turku, Finland, 7Turku University Central Hospital, Turku, Finland, 8Alvar Aallontie 275, Turku University Central Hospital, Turku, Finland, 9Tampere University Hospital, Tampere, Finland, 10Department of Rheumatology, Päijät-Häme Central Hospital, Lahti, Finland, 11Päijät-Häme Central Hospital, Lahti, Finland

    Background/Purpose: Finnish national combination treatment trials have demonstrated excellent outcomes in patients with ERA including 90% of patients reaching DAS28 remission at 6 months. Whether…
  • Abstract Number: 3181 • 2015 ACR/ARHP Annual Meeting

    How Common Is Inactive Disease in a Prospective Cohort of Patients with Juvenile Idiopathic Arthritis? the Importance of Definition

    Stephanie Shoop1, Suzanne M. Verstappen2, Eileen Baildam3, Alice Chieng4, Joyce Davidson5,6, Helen Foster7, Yiannis Ioannou8, Flora McErlane7, Lucy R Wedderburn9, Wendy Thomson10 and Kimme L. Hyrich10, 1ARC Epidemiology, Stopford Building, ARC Epidemiology Unit, The University of Manchester, M13 9PT, United Kingdom, 2ARC Epidemiology, Stopford Building, ARC Epidemiology Unit, the University of Manchester, Manchester, United Kingdom, 3Paediatric Rheumatology, Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom, 4Royal Manchester Children's Hospital, Manchester, United Kingdom, 5The Royal Hospital for Sick Children, Glasgow, Glasgow, United Kingdom, 6The Royal Hospital for Sick Children, Edinburgh, Edinburgh, United Kingdom, 7Royal Victoria Hospital, Newcastle, United Kingdom, 8Rayne Institute, University College London, London, UK, London, United Kingdom, 9Great Ormond Street Hospital NHS Foundation Trust, Paediatric Rheumatology, London, United Kingdom, 10arc Epidemiology Unit, Manchester, United Kingdom

    Background/Purpose: Patients with JIA are at risk of disability, pain and joint damage in the longer-term. Treating toward clinically inactive disease (ID) has the potential…
  • Abstract Number: 504 • 2015 ACR/ARHP Annual Meeting

    Influence of CDAI Measurement on the Decision of Community Rheumatologists to Initiate or Change Biologic Treatment

    Alan K. Matsumoto1, Herbert S. B. Baraf2, Janna Radtchenko3, Jason Drenning4 and Bruce Feinberg5, 1Rheumatology, Arthritis & Rheumatism Assoc, Wheaton, MD, 2The Center for Rheumatology and Bone Research, Wheaton, MD, 3Health Care Analytics, Cardinal Health, Dallas, TX, 4Healthcare Analytics, Cardinal health, Dallas, TX, 5Cardinal Health, Dublin, OH

    Background/Purpose: Periodic measurement of disease activity using validated tools such as the Clinical Disease Activity Index (CDAI) is considered an important aspect of care for…
  • Abstract Number: 3185 • 2015 ACR/ARHP Annual Meeting

    A Cluster-Randomized Trial of a Behavioral Intervention to Incorporate a Treat-to-Target Approach in the Clinical Care of Rheumatoid Arthritis Patients in the United States

    Leslie Harrold1,2, George W. Reed1,2, J. Timothy Harrington3, Christine J. Barr1, Katherine C. Saunders1, Allan Gibofsky4, Eric M. Ruderman5, Tmirah Haselkorn6, Jeffrey D. Greenberg1,7, Ani John6 and Joel M. Kremer8, 1Corrona, LLC, Southborough, MA, 2University of Massachusetts Medical School, Worcester, MA, 3Joiner Associates, LLC, Madison, WI, 4Hospital for Special Surgery, New York, NY, 5Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 6Genentech, Inc, South San Francisco, CA, 7NYU School of Medicine, New York, NY, 8Albany Medical College and The Center for Rheumatology, Albany, NY

    Background/Purpose: We report the results of a cluster-randomized behavioral intervention trial designed to assess the impact of implementing a treat-to-target (T2T) approach vs usual care…
  • Abstract Number: 506 • 2015 ACR/ARHP Annual Meeting

    Evaluation of Persistence and Outcomes in Patients Treated with TNF and Non-TNF Biologics Following Treatment Clinical Pathway in Rheumatoid Arthritis

    Alan K. Matsumoto1, Herbert S. B. Baraf2, Janna Radtchenko3, Jason Drenning4 and Bruce Feinberg5, 1Rheumatology, Arthritis & Rheumatism Assoc, Wheaton, MD, 2The Center for Rheumatology and Bone Research, Wheaton, MD, 3Health Care Analytics, Cardinal Health, Dallas, TX, 4Healthcare Analytics, Cardinal health, Dallas, TX, 5Cardinal Health, Dublin, OH

    Background/Purpose: Use of biologic agents for the treatment of rheumatoid arthritis continues to grow rapidly, with the cost of these agents putting a significant strain…
  • Abstract Number: 580 • 2015 ACR/ARHP Annual Meeting

    Treatment with Biologic Agents in Rheumatoid Arthritis and Mortality Risk in Clinical Practice

    Leticia Leon1, Luis Rodriguez-Rodriguez1, Alejandro Gomez-Gomez2, Pilar Macarrón2, Margarita Blanco2, Juan A Jover2 and Lydia Abasolo1, 1Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, 2Rheumatology, Hospital Clínico San Carlos, Madrid, Spain

    Background/Purpose: It is a well-known fact the decline of life expectancy in Rheumatoid Arthritis (RA) being the increased mortality in these patients a constant concern…
  • Abstract Number: 682 • 2015 ACR/ARHP Annual Meeting

    Misalignment Between Physician and Patient Satisfaction with Current Psoriatic Arthritis Treatment

    Daniel E. Furst1, Emma Sullivan2, James Pike3, James Piercy4, Jacqueline Palmer5 and Vivian Herrera5, 1Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 2Adelphi Real World, Manchester, United Kingdom, 3Statistics, Adelphi Real World, Macclesfield, United Kingdom, 4Adelphi Real World, Macclesfield, United Kingdom, 5Novartis Pharmaceuticals Corporation, East Hanover, NJ

    Background/Purpose: Psoriatic Arthritis (PsA) is a chronic immune related condition affecting the joints and commonly occurs alongside psoriasis. Well-established physician patient relationships are instrumental to…
  • Abstract Number: 1276 • 2015 ACR/ARHP Annual Meeting

    Improvement in Work and Household Productivity for Patients with Rheumatoid Arthritis and Ankylosing Spondylitis Treated with Anti-TNFs in Routine Clinical Practice in Turkey

    Sebnem Ataman1, Mehmet Kirnap2, Buminhan Seferoglu3, Zuhal Altay4, Aylin Rezvani5, Omer Kuru6,7, Erhan Capkin8, Nazli Derya Bugdayci9, Ilhan Sezer10, Hasan Fatih CAY11 and Akinci Tan12, 1Rheumatology Department, Ankara University Faculty of Medicine, Ankara, Turkey, 2Department of Physical Medicine and Rehabilitation, Erciyes University, Kayseri, Turkey, 3Physical Medicine and Rehabilitation, Ataturk University Medical School, Erzurum, Turkey, 4ELAZIG KARAYOLU UZERI, Inonu University, Turgut Ozal Medical Center, Malatya, Turkey, 5Department of Physical Medicine and Rehabilitation, Bezmialem Foundation University, İstanbul, Turkey, 6Kurupelit Mevkii Kurupelit 552, Ondokuz Mayis Univ.Tip Fak.Has.-Fizik Tedavi, Samsun, Turkey, 7Physical Medicine and Rehabilitation, Ondokuz Mayis University, Samsun, Turkey, 8PM&R AND RHEUMATOLOGY, Karadeniz Tecnical University, Faculty of Medicine, TRABZON, Turkey, 9Physical Treatment and Rehabilitation, Istanbul Physical Treatment and Rehabilitation Training and Research Hospital, Istanbul, Turkey, 10Rheumatology, Physical Medicine and Rheabilitation, Antalya Education and Research Hospital, Antalya, Turkey, 11Rheumatology, Physical Medicine&Rehabilitation, Antalya Education and Research Hospital, Antalya, Turkey, 12Physical Med & Rehab, Hacettepe Univ, Ankara, Turkey

    Background/Purpose: The impact of  rheumatoid arthritis (RA) and ankylosing spondylitis (AS)  on paid work is measured on the basis of employed people missing time from…
  • Abstract Number: 1655 • 2015 ACR/ARHP Annual Meeting

    Effectiveness of Monotherapy in Rheumatoid Arthritis (RA) Patients Initiating a Tumor Necrosis Factor Inhibitor (TNFi) Vs a Non-TNFi in a Large US Commercial and Medicare Advantage Plan

    Benjamin Chastek1, Jeffrey R. Curtis2, Laura K. Becker3, George J. Joseph4 and Chieh-I Chen5, 1Optum Insight, Eden Prairie, MN, 2University of Alabama at Birmingham, Birmingham, AL, 3Optum, Eden Prairie, MN, 4Global Health Economics & Outcomes Research (HEOR), Sanofi, Bridgewater, NJ, 5Regeneron Pharmaceuticals, Inc., Tarrytown, NY

    Background/Purpose: Monotherapy accounts for approximately 30% of biologic disease-modifying anti-rheumatic drug (DMARD) use in RA (Emery P et al. Ann Rheum Dis 2013;72:1897-904). A validated…
  • Abstract Number: 1715 • 2015 ACR/ARHP Annual Meeting

    Sensivity and Specificity of Clinical Criteria to Identify Patients in Ultrasound Remission in Psoriatic Arthritis

    Brigitte Michelsen1, Andreas P Diamantopoulos2, Hilde Berner Hammer3, Arthur Kavanaugh4 and Glenn Haugeberg1,5,6, 1Rheumatology, Hospital of Southern Norway Trust, Kristiansand, Norway, 2Haugesund Rheumatism Hospital, Haugesund, Norway, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4University of California, San Diego School of Medicine, LaJolla, CA, 5Rheumatology, The Norwegian University of Science and Technology, Trondheim, Norway, 6Rheumatology, Martina Hansens Hospital, Gjettum, Norway

    Background/Purpose: To date, although several have been proposed, there are no validated remission criteria in psoriatic arthritis (PsA). Validated criteria for minimal disease activity (MDA) in…
  • Abstract Number: 1717 • 2015 ACR/ARHP Annual Meeting

    Factors Associated with the Decision of the Rheumatologist to Order Sacro-Iliac Joints Magnetic Resonance Imaging (SI-MRI) or Order HLA-B27 Testing in Patients with Spondyloarthritis in Clinical Practice

    Wilson Bautista-Molano1,2, Robert Landewé3, Cesar Serna4, Rafael R. Valle5 and Désirée van der Heijde6, 1Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, 2Department of Rheumatology, Faculty of Medicine HMC/UMNG, Bogota, Colombia, Bogotá, Colombia, 3Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, 4Statistics and Mathematics Department, Universidad Central, Bogotá, Colombia, Bogotá, Colombia, 5Rheumatology/Immunology, Department of Rheumatology, Faculty of Medicine HMC/UMNG, Bogota, Colombia, Bogota, Colombia, 6Dept. of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Magnetic resonance imaging of sacroiliac joints (MRI-SI) and HLA-B27 testing are important tools in the diagnosis of spondyloarthritis (SpA). The aim of the study…
  • Abstract Number: 1977 • 2015 ACR/ARHP Annual Meeting

    Long-Term Survival of Methotrexate in Giant Cell Arteritis Patients in Clinical Practice

    Dalifer Freites Núñez1, Zulema Rosales1,2, Lucía Arietti1, Leticia Leon2, Inmaculada Morado1, Benjamín Fernández-Gutiérrez3, Luis Rodriguez-Rodriguez2, Juan A Jover1 and Lydia Abasolo2, 1Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, 2Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, 3Department of Rheumatology, Hospital Clínico San Carlos, Madrid, Spain

    Background/Purpose: It has is been demonstrated the safety and efficacy of Methotrexate (MTX) in the treatment of Giant Cell Arteritis (GCA) in clinical trials, but…
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