Abstracts tagged "citrullination and proteomics"

Abstract Number: 55 • 2016 ACR/ARHP Annual Meeting
Identification of Endogenous Autoantigens Bound to Anti-Citrullinated Peptide Antibodies in Rheumatoid Arthritis: A Key Role for Citrulline Residues in Histone 4
Xiaobo Meng¹, Peyman Ezzati¹, Irene Smolik², Carol Hitchon³ and Hani El-Gabalawy⁴, ¹UNIVERSITY OF MANITOBA, WINNIPEG, MB, Canada, ²Arthritis Center, University of Manitoba, Winnipeg, MB, Canada, ³University of Manitoba, Winnipeg, MB, Canada, ⁴University of Manitoba Arthritis Center, Winnipeg, MB, Canada
Background/Purpose: Anti-Citrullinated Peptides Antibodies (ACPA) aid in rheumatoid arthritis (RA) diagnosis. The nature of autoantigens specifically bound to ACPA immune complex in vivoremains unclear. We…

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Abstracts tagged "citrullination and proteomics"

Identification of Endogenous Autoantigens Bound to Anti-Citrullinated Peptide Antibodies in Rheumatoid Arthritis: A Key Role for Citrulline Residues in Histone 4